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Apparatus for monitoring glucose

  • US 4,981,779 A
  • Filed: 06/26/1986
  • Issued: 01/01/1991
  • Est. Priority Date: 06/26/1986
  • Status: Expired due to Fees
First Claim
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1. An apparatus for monitoring glucose concentration in a body fluid comprising:

  • (a) a first cable comprising first and second optical fibers having immobilized thereon a first conjugate comprising active glucose oxidase and a fluorescent dye, emission from said dye being sensitive to oxygen quenching;

    (b) a second cable comprising third and fourth optical fibers having immobilized thereon a second conjugate comprising inactive glucose oxidase and the same aforementioned fluorescent dye;

    (c) a light source in excitation light transmissive communication with said first conjugate through said first fiber and with said second conjugate through said third fiber; and

    (d) a detector in fluorescence emission transmissive communication with said first conjugate through said second fiber and with said second conjugate through said fourth fiber.

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