Exercise responsive cardiac pacemaker
First Claim
1. A rate-responsive cardiac therapy device, comprising:
- a reference-temperature memory;
a current-temperature sensor;
a cardiac rate control signal generator having one input coupled to said reference-temperature memory and another input coupled to said current-temperature sensor;
a cardiac pulse generator having an input coupled to said cardiac rate control signal generator;
a differentiator having an input coupled to said current-temperature sensor and an output coupled to said cardiac rate control signal generator; and
a base-heart-rate memory having an output coupled to said cardiac rate control signal generator;
wherein said cardiac rate control signal generator includes means responsive to said base-heart-rate memory for determining a first rate control factor;
means responsive to said reference-temperature memory and said current-temperature sensor for determining a second rate control factor proportional to the difference between current temperature and reference temperature;
means coupled to said differentiator for determining the sign of the derivative and for determining a third rate control factor therefrom; and
means for adding said first, second and third factors to form a cardiac rate control signal.
0 Assignments
0 Petitions
Accused Products
Abstract
An exercise-responsive cardiac pacemaker is provided which physiologically controls the stimulation rate of a heart by sensing the venous blood temperature in the right ventricle of the heart. A temperature sensing means which includes a thermistor produces an output signal which is sent to an algorithm implementing means for implementing the output signal by an algorithm which represents the mathematical function between venous blood temperature in the right ventricle and heart rate in a normally functioning heart. The algorithm implementing means produces an output signal which is variable between a maximum and minimum level corresponding to the desired maximum and minimum levels of heart rate in a normally functioning heart. The algorithm implementing means is also programmable by telemetry after implantation. A cardiac pacemaker is connected to the algorithm implementing means and is responsive thereto in order to variably control the stimulation rate of the heart.
51 Citations
15 Claims
-
1. A rate-responsive cardiac therapy device, comprising:
-
a reference-temperature memory; a current-temperature sensor; a cardiac rate control signal generator having one input coupled to said reference-temperature memory and another input coupled to said current-temperature sensor; a cardiac pulse generator having an input coupled to said cardiac rate control signal generator; a differentiator having an input coupled to said current-temperature sensor and an output coupled to said cardiac rate control signal generator; and a base-heart-rate memory having an output coupled to said cardiac rate control signal generator; wherein said cardiac rate control signal generator includes means responsive to said base-heart-rate memory for determining a first rate control factor; means responsive to said reference-temperature memory and said current-temperature sensor for determining a second rate control factor proportional to the difference between current temperature and reference temperature; means coupled to said differentiator for determining the sign of the derivative and for determining a third rate control factor therefrom; and means for adding said first, second and third factors to form a cardiac rate control signal. - View Dependent Claims (2)
-
-
3. A rate-responsive cardiac therapy device, comprising:
-
means for storing a reference temperature measured at a predetermined location in the body of an individual subject; means for measuring a current temperature at the predetermined location in the body of the individual subject; means for determining a rate control factor based on the difference between the current temperature and the reference temperature; cardiac pulse generator means for generating cardiac pulses at a rate responsive to said rate control factor; means coupled to said measuring means for calculating the rate of change of temperature; and means for storing a base heart rate, wherein said cardiac pulse generator means includes means for generating cardiac pulses at a rate dependent on said base heart rate in addition to said rate control factor and the calculated rate of change of temperature. - View Dependent Claims (4, 5)
-
-
6. A method of providing rate-responsive cardiac therapy, comprising the steps:
-
storing a reference temperature measured at a predetermined location in the body of an individual subject; measuring a current temperature at the predetermined location in the body of the individual subject; determining a rate control factor proportional to the difference between the current temperature and the reference temperature; generating cardiac pulses at a rate responsive to said rate control factor; calculating the rate of change of temperature; and storing a base heart rate, wherein said generating step includes generating cardiac pulses at a rate dependent on said base heart rate in addition to said rate control factor and the calculated rate of change of temperature. - View Dependent Claims (7, 8)
-
-
9. A rate-responsive cardiac therapy device, comprising:
-
a temperature sensor; a reference-temperature memory; and a cardiac pulse generator, said pulse generator including rate control means for controlling the rate of generation of cardiac pulses, said rate control means including means coupled to said temperature sensor for determining rate of change of temperature; means responsive to said means for determining rate of change of temperature for determining a first rate control factor as a function of calculated rate of change of temperature; means responsive to said reference-temperature memory and said temperature sensor for determining a second rate control factor proportional to the difference between current temperature and reference temperature; and combining means for obtaining a selected combination of said first and second rate control factors and for forming a cardiac rate control signal therefrom. - View Dependent Claims (10, 11)
-
-
12. A method of controlling rate in a rate-responsive cardiac therapy device, comprising the steps:
-
measuring temperature at a predetermined location in the body of an individual subject; determining the rate of change of the temperature measured in said measuring step; determining a first rate control factor as a function of the rate of change of temperature; storing a reference temperature; subtracting the stored reference temperature from the temperature measured in said measuring step; storing a base heart rate; determining a second rate control factor proportional to said temperature difference obtained in said subtracting step; and generating cardiac pulses at a rate responsive to said first rate control factor, said generating step including adding said base heart rate to said first and second rate control factors.
-
-
13. A method of controlling rate in a rate-responsive cardiac therapy device, comprising the steps:
-
measuring temperature at a predetermined location in the body of an individual subject; determining the rate of change of the temperature measured in said measuring step; determining a first rate control factor as a function of the rate of change of temperature; storing a reference temperature; determining a second rate control factor proportional to the difference between current temperature and said reference temperature; and generating cardiac pulses at a rate responsive to said first rate control factor, said generating step including selectively combining said first and second rate control factors to form a cardiac rate control signal. - View Dependent Claims (14, 15)
-
Specification