Travenously placed defibrillation leads

• US 4,998,975 A
• Filed: 10/30/1989
• Issued: 03/12/1991
• Est. Priority Date: 10/30/1989
• Status: Expired due to Fees

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Siemens Pacesetter, Inc. (Abbott Laboratories)
• Inventors: Thacker, James R., Cohen, Donald M.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/429,440
• Time in Patent Office: 498 Days
• Field of Search: 128/419 D, 128/419 P, 128/784, 128/785, 128/786, 128/639, 128/642
• US Class Current: 607/5
• CPC Class Codes: A61N 1/0563 specially adapted for defibrillation or cardioversion
• CPC Class Codes: A61N 1/0587 Epicardial electrode systems; Endocardial electrodes piercing the pericardium
• CPC Class Codes: A61N 1/3918 characterised by shock pathway, e.g. by electrode configuration

Abstract

A cardiac defibrillation system and method includes an epicardial electrode for making electrical contact with the epicardium from a position within the pericardial space, an endocardial electrode for making electrical contact with the endocardium of the heart, and means for making electrical contact with the epicardial and endocardial electrodes. The endocardial electrode is inserted transvenously into the heart in conventional manner. The epicardial electrode is also inserted transvenously into the heart, through the heart wall, and into the pericardial space. No open chest surgery is required.

Claims

1. A cardiac defibrillation system comprising:

an epicardial electrode for making physical contact with the epicardium of a human heart from a position within the pericardial space of the heart;

means for transvenously inserting said epicardial electrode into the pericardial space;

an endocardial electrode for making physical contact with the endocardium of the heart; and

means for selectively placing a momentary electrical potential between said epicardial and endocardial electrodes, said momentary electrical potential being sufficient to cause a momentary pulse of electrical energy to be delivered to the myocardial tissue intermediate said epicardial and endocardial electrodes;

said electrical energy being sufficient to cause the myocardium of the heart to depolarize.

2. The cardiac defibrillation system, as set forth in claim 1, wherein said epicardial electrode comprises a plurality of spaced-apart epicardial electrode segments, each of said plurality of spaced-apart epicardial electrode segments being electrically connected to said means for placing a momentary electrical potential.

3. The cardiac defibrillation system, as set forth in claim 2, wherein said means for selectively placing a momentary electrical potential between said epicardial and endocardial electrodes includes means for adjusting the magnitude of the electrical potential placed between each of said plurality of spaced-apart epicardial electrode segments and said endocardial electrode, whereby the depolarization energy delivered to the heart is selectively directed to desired areas of the heart.

4. The cardiac defibrillation system, as set forth in claim 3, further including means for measuring a parameter related to the myocardial tissue between each of said spaced-apart epicardial electrode segments and said endocardial electrode, and wherein said means for adjusting the magnitude of the electrical potential placed between each of said plurality of spaced-apart electrode segments and said endocardial electrode includes means for adjusting the magnitude of the electrical potential as a function of said measured parameter.

5. The cardiac defibrillation system, as set forth in claim 4, wherein said parameter related to the myocardial tissue between said endocardial electrode and said plurality of spaced-apart epicardial electrode segments comprises impedance.

6. The cardiac defibrillation system, as set forth in claim 2, wherein said plurality of spaced-apart epicardial electrode segments in combination with said endocardial electrode concentrate the defibrillation energy in the left ventricle of the heart.

7. The cardiac defibrillation system, as set forth in claim 6, wherein said endocardial electrode is positioned proximate the septum of the heart within the right ventricle.

8. The cardiac defibrillation system, as set forth in claim 6, wherein said endocardial electrode comprises a plurality of spaced-apart endocardial electrode segments.

9. A cardiac defibrillation system comprising:

an endocardial electrode for making physical contact with the endocardium of a heart;

a plurality of spaced-apart epicardial electrodes for making physical contact with the epicardium of a human heart from a position within the pericardial space of the heart, said epicardial electrodes being transvenously insertable into the pericardial space; and

lead means for making electrical contact with said epicardial electrodes from a location removed from said heart, said lead means comprising an elongate flexible electrical conductor having an electrically insulating sheath therearound, said electrical conductor and sheath comprising a lead body, said spaced-apart electrodes being positioned near a distal end of said lead body, and further wherein said epicardial electrodes comprise a segment of conductive material having a circumference not substantially greater than the circumference of said lead body;

whereby an electrical potential of sufficient magnitude placed between said endocardial and epicardial electrodes by way of said electrical contact means triggers the depolarization of myocardial tissue proximate said electrodes.

10. The implantable defibrillation lead, as set forth in claim 9, further including a plurality of branches splitting off from the lead body near the distal end thereof, each of said branches having a length, at least one of said epicardial electrodes being positioned along said length of each branch.

11. The implantable defibrillation lead, as set forth in claim 9, wherein the distal end of said lead body comprises a loop, said loop being adapted to fit around a section of the heart, at least two of said plurality of spaced-apart epicardial electrodes being placed in electrical contact with said flexible electrical conductor at designated locations on said loop.

12. An implantable defibrillation lead system comprising:

a plurality of spaced-apart epicardial electrodes for making physical contact with the epicardium of a human heart from a position within the pericardial space of the heart, said epicardial electrodes being transvenously insertable into the pericardial space; and

a plurality of spaced-apart endocardial electrodes for making physical contact with the endocardium of the heart; and

first and second elongate flexible electrical conductors, each having an electrically insulating sheath therearound, said electrical conductor and sheath of each comprising a first and second lead body, respectively, said spaced-apart epicardial electrodes being positioned near a distal end of said first lead body, and said spaced-apart endocardial electrodes being positioned near a distal end of said second lead body;

said spaced-apart epicardial electrodes comprising segments of conductive material in electrical contact with said first elongate flexible conductor and having a circumference not substantially greater than the circumference of said first lead body;

whereby an electrical potential of sufficient magnitude placed between said epicardial and endocardial electrodes through said first and second elongate flexible electrical conductors triggers the depolarization of myocardial tissue proximate said endocardial and epicardial electrodes.

13. The implantable defibrillation lead system, as set forth in claim 12, further including a plurality of branches splitting off from the first lead body near the distal end thereof, each of said branches having a length, at least one of said spaced-apart epicardial electrodes being positioned along the length of each of said branches.

14. The implantable defibrillation lead system, as set forth in claim 12, wherein the distal end of said first lead body comprises a loop, said loop being adapted to fit around a section of the heart, at least two of said plurality of spaced-apart epicardial electrodes being placed in electrical contact with said first flexible electrical conductor at designated locations on said loop.

15. An implantable defibrillation system, as set forth in claim 12, wherein said second lead body includes:

a plurality of branches splitting off from said second lead body near the distal end thereof, each of said branches having a length, at least one of said spaced-apart endocardial electrodes being positioned along the length of each branch; and

anchoring means for anchoring the distal end of said branches near the apex of the heart so as to place said spaced-apart endocardial electrodes in contact with the septum of the heart.

16. An implantable endocardial defibrillation lead system, as set forth in claim 15, wherein said anchoring means comprises screw-in helixes, fins or porous electrodes.

17. The implantable defibrillation lead system, as set forth in claim 15, further comprising:

resistance means intermediate said spaced-apart epicardial electrodes for placing an electrical resistance in series with said spaced-apart epicardial electrodes, whereby said first elongate flexible electrical conductor and said spaced-apart epicardial electrodes function as a first voltage divider network relative to said plurality of spaced-apart endocardial electrodes.

18. The implantable defibrillation lead system, set forth in claim 17, wherein said plurality of spaced-apart endocardial electrodes comprises:

a first endocardial electrode, directly connected to said second elongate flexible electrical conductor, said first electrical conductor having a first resistance; and

a second endocardial electrode, connected to said first endocardial electrode through a second resistance.

19. An implantable endocardial defibrillation lead comprising:

a plurality of spaced-apart endocardial electrodes for making physical and electrical contact proximate the septum of a heart;

a lead body having a plurality of branches spitting off from said body near a distal end thereof, each of said branches having a length, at least one of said plurality of endocardial electrodes being positioned along the length of each branch,

and anchoring means for anchoring said branches near the apex of the heart so as to place said spaced-apart endocardial electrodes in contact with the septum of the heart, wherein said anchoring means comprises screw-in helixes, fins or porous electrodes.

20. A method of defibrillating a human heart comprising the steps of:

(a) transvenously inserting an epicardial electrode into the pericardial space surrounding the heart;

(b) positioning said epicardial electrode so that it makes electrical contact with a desired area of the epicardium;

(c) transvenously inserting an endocardial electrode inside of the heart;

(d) positioning said endocardial electrode so that it makes electrical contact with a desired area of the endocardium; and

(e) applying an electrical potential between said epicardial and endocardial electrodes;

said electrical potential triggering the depolarization of myocardial tissue proximate said epicardial and endocardial electrodes.

21. The method of defibrillating a heart, as set forth in claim 20, wherein step (a) comprises transvenously inserting a plurality of spaced-apart epicardial electrodes into the pericardial space surrounding the heart.

22. The method of defibrillating a heart, as set forth in claim 21, wherein step (b) comprises positioning at least a plurality of said epicardial electrodes so that they contact epicardial tissue of the left ventricle.

23. The method of defibrillating a heart, as set forth in claim 22, wherein step (d) comprises positioning said endocardial electrode so that it contacts the septum of the heart from a position within the right ventricle.

24. The method of defibrillating a heart, as set forth in claim 23, wherein step (e) comprises applying an electrical potential of different magnitudes to different ones of said epicardial and endocardial electrodes for the purpose of directing different levels of defibrillation energy to selected areas of the heart.

25. The method of defibrillating a heart, as set forth in claim 23, wherein step (e) further comprises the steps of:

measuring impedance of the myocardial tissue between said epicardial and endocardial electrodes; and

adjusting the magnitude of the electrical potential on each electrode as a function of said measured impedance.

26. The method of defibrillating a heart, as set forth in claim 23, further comprising the steps of:

measuring impedance of the myocardial tissue between said epicardial and endocardial electrodes; and

repositioning said endocardial and epicardial electrodes based on said measured value of the myocardial tissue so that the defibrillation energy required to defibrillate the heart is minimized.

27. A method of defibrillating a human heart comprising the steps of:

(a) transvenously inserting a plurality of spaced-apart epicardial electrodes into the pericardial space surrounding the heart;

(b) positioning at least a plurality of said epicardial electrodes so that they contact epicardial tissue of the left ventricle;

(c) transvenously inserting an endocardial electrode inside of the heart;

(d) positioning said endocardial electrode so that it makes electrical contact with the septum of the heart from a position within the right ventricle; and

(e) applying an electrical potential between said epicardial and endocardial electrodes;

said electrical potential triggering the depolarization of myocardial tissue proximate said epicardial and endocardial electrodes.

28. The method of defibrillating a heart, as set forth in claim 27, wherein step (e) comprises applying an electrical potential of different magnitudes to different ones of said epicardial and endocardial electrodes for the purpose of directing different levels of defibrillation energy to selected areas of the heart.

29. The method of defibrillating a heart, as set forth in claim 27, wherein step (e) further comprises the steps of:

measuring impedance of the myocardial tissue between said epicardial and endocardial electrodes; and

adjusting the magnitude of the electrical potential on each electrode as a function of said measured impedance.

30. The method of defibrillating a heart, as set forth in claim 27, further comprising the steps of:

measuring the impedance of the myocardial tissue between said epicardial and endocardial electrodes; and

repositioning said endocardial and epicardial electrodes based on said measured value of the myocardial tissue so that the defibrillation energy required to defibrillate the heart is minimized.