Cardiac synchronization magnetic resonance imaging
First Claim
1. A method of magnetic resonance cardiac imaging comprising:
- generating a main magnetic field through an image region;
monitoring a plurality of cardiac cycles of a patient at least partially disposed in the image region, each of the plurality of cardiac cycles having at least one preselected identifiable point;
projecting a time of occurrence of the preselected identifiable point in a subsequent cycle;
applying an inversion pulse a preselected duration before the projected preselected identifiable point of the subsequent cardiac cycle, the inversion pulse inverting the longitudinal magnetization of blood and cardiac tissue recovering at different rates;
conducting a magnetic resonance imaging sequence in coordination with the preselected identifiable point in the subsequent cycle to induce magnetic resonance signals to be emitted from blood and cardiac tissue in the image region;
acquiring and reconstructing the magnetic resonance signals into an image representation.
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Accused Products
Abstract
A cardiac monitor (62, 64) monitors the cardiac cycles of a patient in an examination region (10). Each cardiac cycle includes an R-wave (40) at the beginning of the end-diastole. A conditioning pulse trigger (74) enables a preconditioning pulse control (34) to generate a conditioning pulse (42) at a time selected in accordance with the R-wave (40n-1) of one cardiac cycle. More specifically, an R-wave predictor (72) predicts when the next R-wave (40n) will occur and the conditioning pulse trigger enables the application of the conditioning pulse (42n) a selected duration before the next predicted R-wave (40n). An imaging sequence trigger (78) enables an image sequence controller (24) to start an imaging sequence in an imaging window (44n) in conjunction with the R-wave (40n). Preferably, the imaging sequence starts immediately with the R-wave (40n) such that the end-diastole stage of the heart is imaged. In this manner, a conditioning pulse, such as an inversion pulse or a saturation pulse, is applied in one cardiac cycle to affect the imaging sequence in the next cardiac cycle. The application of the preconditioning pulse is timed such that the longitudinal magnetization of the blood (54) is near zero (56) during the imaging sequence while the transverse magnetization of cardiac tissue (52) has substantially recovered by the imaging sequence.
60 Citations
15 Claims
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1. A method of magnetic resonance cardiac imaging comprising:
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generating a main magnetic field through an image region; monitoring a plurality of cardiac cycles of a patient at least partially disposed in the image region, each of the plurality of cardiac cycles having at least one preselected identifiable point; projecting a time of occurrence of the preselected identifiable point in a subsequent cycle; applying an inversion pulse a preselected duration before the projected preselected identifiable point of the subsequent cardiac cycle, the inversion pulse inverting the longitudinal magnetization of blood and cardiac tissue recovering at different rates; conducting a magnetic resonance imaging sequence in coordination with the preselected identifiable point in the subsequent cycle to induce magnetic resonance signals to be emitted from blood and cardiac tissue in the image region; acquiring and reconstructing the magnetic resonance signals into an image representation. - View Dependent Claims (2, 3)
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4. A method of magnetic resonance imaging of a cyclically moving organ comprising:
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generating a main magnetic field through an image region; monitoring a plurality of cycles of the cyclically moving organ of a patient at least partially in the image region, each of the plurality of cycles having at least one preselected identifiable point; projecting a time of occurrence of the preselected identifiable point in a subsequent cycle; applying a preconditioning radio frequency pulse a preselected duration before the projected preselected identifiable point of the subsequent cycle; conducting a magnetic resonance imaging sequence in coordination with the preselected identifiable point of the subsequent cycle; acquiring magnetic resonance signals induced by the imaging sequence; reconstructing an image representation from the acquired magnetic resonance signals. - View Dependent Claims (5, 6, 7)
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8. A method of magnetic resonance cardiac imaging comprising:
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(a) positioning a patient in an imaging region through which a strong magnetic field is generated; (b) monitoring a cardiac cycle of the patient to determine the occurrence of an R-wave; (c) projecting an occurrence of a next R-wave in a subsequent cardiac cycle; (d) a preselected duration before the projected next R-wave, applying a radio frequency preconditioning pulse which rotates the longitudinal magnetization of selected nuclei to be imaged; (e) conducting an imaging sequence in a coordinated time relationship with the next R-wave; (f) acquiring magnetic resonance data induced by the imaging sequence; (g) reconstructing an image representation from the acquired data. - View Dependent Claims (9, 10, 11, 12)
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13. A method of magnetic resonance imaging of a cyclically pulsating organ, the method comprising:
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creating a static magnetic field through an image region that encompasses the pulsating organ; conducting an imaging sequence in each of a plurality of contiguous organ cycles to cause magnetic resonance signals to be emitted from the image region; acquiring the resonance signals and reconstructing an image representation therefrom; projecting an occurrence of an identifiable point in a next organ cycle; applying a preconditioning pulse following each imaging sequence and a preselected duration before the projected occurrence of the identifiable point in the next organ cycle such that the resonance signals acquired from the imaging sequence conducted in a next organ cycle are affected by the preconditioning pulse.
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14. A magnetic resonance apparatus comprising:
- means for creating a magnetic field through an image region in which a patient is at least partially disposed;
an imaging sequence means for applying an imaging sequence of radio frequency and gradient magnetic field pulses in the image region to generate magnetic resonance image data; a preconditioning pulse means for applying a preconditioning radio frequency pulse in the image region, the radio frequency preconditioning pulse affecting a subsequent imaging sequence; a cardiac monitor means for monitoring cardiac cycles of the patient; a projecting means for projecting an occurrence of a preselected identifiable point in a next cardiac cycle, the projecting means being connected with the cardiac monitor means; a first enabling means for enabling the preconditioning pulse means to apply the preconditioning pulse a preselected duration before the occurrence of the projected preselected identifiable point in the next cardiac cycle, the first enabling means being connected with the projecting means and the preconditioning pulse means; a second enabling means for enabling the imaging sequence for applying the imaging sequence in coordination with the preselected identifiable point of the next cardiac cycle, the second enabling means being connected to the cardiac monitoring means and the imaging sequence means such that each imaging sequence is affected by the preconditioning pulse applied during a preceding cardiac cycle. - View Dependent Claims (15)
- means for creating a magnetic field through an image region in which a patient is at least partially disposed;
Specification