Method of and device for inducing locomotion by electrical stimulation of the spinal cord
First Claim
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1. A method of inducing locomotion in animals comprising electrically stimulating the spinal cord using pulses having a duration between 0.2 msec and 2 msec delivered at frequencies between 0.5 Hz and 20 Hz wherein said stimulation is at a locus on the spinal cord at which such stimulation induces locomotor activity.
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Abstract
A method and device for inducing locomotion in animals by electrical stimulation of the spinal cord using long duration pulses (0.2 msec to 2 msec) delivered at low frequencies (0.5 Hz to 20 Hz) epidurally or subdurally to the dorsal columns or dorsal root entry zone at the cervical or lumbar regions of the spinal cord for treating deficits in locomotion.
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26 Claims
- 1. A method of inducing locomotion in animals comprising electrically stimulating the spinal cord using pulses having a duration between 0.2 msec and 2 msec delivered at frequencies between 0.5 Hz and 20 Hz wherein said stimulation is at a locus on the spinal cord at which such stimulation induces locomotor activity.
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15. A device for generating electrical pulses for inducing locomotion, comprising:
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control means for controlling the generation of electrical signals having a pulse width between about 0.2 msec and about 2 msec and delivered at a frequency between about 0.5 Hz and about 10 Hz for inducing locomotion by direct spinal cord stimulation; and electrode means shaped and dimensioned so as to permit subdural or epidural implantation and connected to said control means, for receiving the signals and applying the signals to the spinal cord, when in use, at a locus at which such stimulation induces locomotor activity. - View Dependent Claims (16, 17, 18)
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19. A device for generating electrical pulses for inducing locomotion in an animal, comprising:
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control means for controlling the generation of electrical signals having a pulse width between about 0.2 msec and about 2 msec and delivered at a frequency between about 0.5 Hz and about 10 Hz for inducing locomotion by direct spinal cord stimulation; transmitter means connected to said control means for transmitting the electrical signals; receiver means for placement under the skin of the animal for receiving the electrical signals and converting the signals into electrical pulses; and electrode means shaped and dimensioned so as to permit subdural or epidural implantation and connected to said receiver means, for transmitting the electrical pulses to the spinal cord, when in use, at a locus at which such stimulation induces locomotor activity. - View Dependent Claims (20, 21, 22)
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23. A method of treating a patient with paraplegia or other disorders which impair locomotion to prosthetically induce walking comprising electrically stimulating the spinal cord of the patient using pulses having a duration of between 0.2 msec to 2 msec and a frequency between 0.5 Hz and 20 Hz wherein said stimulation is at a locus on the spinal cord at which such stimulation induces locomotor activity.
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24. A method of treating a patient with paraplegia or other disorders which impair locomotion where the spinal cord has been completely or partially disconnected from the brainstem, to prosthetically induce walking comprising electrically stimulating the spinal cord of the patient using pulses having a duration of between 0.2 msec to 2 msec and a frequency between 0.5 Hz and 20 Hz wherein said stimulation is at a locus on the spinal cord at which such stimulation induces locomotor activity.
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25. A device for generating electrical pulses for inducing locomotion, comprising:
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control means capable of generating electrical signals having pulse widths of about 0.2 msec through about 2 msec and frequencies of about 0.5 Hz through about 20 Hz; and electrode means shaped and dimensioned so as to permit subdural or epidural implantation and connected to said control means, for receiving the signals generated by said control means and applying the signals to the spinal cord when in use.
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26. A device for generating electrical pulses for inducing locomotion in an animal, comprising:
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control means capable of generating electrical signals having pulse widths of about 0.2 msec through about 2 msec and frequencies of about 0.5 Hz through about 20 Hz; transmitter means connected to said control means for transmitting the electrical signals; receiver means for placement under the skin of the animal for receiving the electrical signals and converting the signals into electrical pulses; and electrode means shaped and dimensioned so as to permit subdural or epidural implantation and connected to said receiver means, for transmitting the electrical pulses produced by said receiver means to the spinal cord, when in use.
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Specification