Biological implant with textured surface
First Claim
1. A mass transfer device for implantation in soft tissue, said device including a supporting member having an outer surface textured to define a regular array of micropillars with valleys therebetween, said textured surface comprising means for minimizing fibrous capsule formation and promoting mass transfer in soft tissue in the form of each of said micropillars having a height no less than 100 microns and a width no greater than 5000 microns, with adjacent micropillars in said array being spaced apart a distance no greater than 5000 microns.
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Accused Products
Abstract
An implant for soft tisse (e.g., subcutaneous, perivascular, adipose), particularly a mass transfer device having a fluid diffusing or transmitting surface in contact with the soft tissue, in which the surface of the device in tissue contact is textured to provide a regular pattern of micropillars at least 100 microns in height with transverse dimensions and interpillar spacing each no greater than 5000 microns.
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Citations
9 Claims
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1. A mass transfer device for implantation in soft tissue, said device including a supporting member having an outer surface textured to define a regular array of micropillars with valleys therebetween, said textured surface comprising means for minimizing fibrous capsule formation and promoting mass transfer in soft tissue in the form of each of said micropillars having a height no less than 100 microns and a width no greater than 5000 microns, with adjacent micropillars in said array being spaced apart a distance no greater than 5000 microns.
- 2. A mass transfer device for implantation in soft tissue, said device including a supporting member having an outer surface textured to define a regular array of micropillars with valleys therebetween, each o said micropillars having a height no less than 100 microns and a width no greater than 5000 microns, with adjacent micropillars in said array being spaced apart a distance no greater than 5000 microns, and a thin diffusion membrane covering said micropillars and valleys and conforming with the surface contour of said member, said member being electrically conductive and including in its composition of catalyst capable of catalyzing a reaction with a selected blood analyte diffusible through said membrane.
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3. A mass transfer device for implantation in soft tissue, said device including a supporting member having an outer surface textured to define a regular array of micropillars with valleys therebetween, said of said micropillars having a a height no less than 100 microns and a width no greater than 5000 microns, with adjacent micropillars in said array being spaced apart a distance no greater than 5000 microns, said member including a reservoir for containing an aqueous solution of a therapeutic agent and a multiplicity of passages extending from said reservoir through said micropillars to the ends thereof, and a thin diffusion membrane covering said micropillars and valleys and conforming with the surface contour of said member.
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4. A mass transfer device for implantation in soft tissue, said device including a supporting member having an outer surface textured to define a regular array of micropillars with valleys therebetween, each of said micropillars having a height no less than 100 microns and width no greater than 5000 microns, with adjacent micropillars in said array being spaced apart a distance no greater than 5000 microns, said member including a reservoir for containing an aqueous solution of a therapeutic agent and a multiplicity of passages extending from said reservoir to discharge apertures at the ends of said micropillars.
Specification