Tissue analysis device

• US 5,002,735 A
• Filed: 07/12/1988
• Issued: 03/26/1991
• Est. Priority Date: 07/12/1988
• Status: Expired due to Fees

• Current Assignee: Mark T. Alberhasky
• Original Assignee: Mark T. Alberhasky
• Inventors: Riehm, James D., Alberhasky, Mark T.
• Primary Examiner(s): Warden, Robert J.
• Assistant Examiner(s): KRYZA, LYNN M
• Application Number:
  US07/217,935
• Time in Patent Office: 987 Days
• Field of Search: 422/99, 422/102, 422/104, 422/68, 422/292, 422/300, 422/58, 436/63, 436/64, 436/813, 435/287, 435/310, 378/28
• US Class Current: 422/82.05
• CPC Class Codes: A61B 10/00 Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis vaccination prophylaxis, vaccination therapy A61B17/20; Sex determination; Ovulation-period determination menstruation tables G06C3/00; Throat striking implements
• CPC Class Codes: A61B 2017/00902 transparent or translucent
• CPC Class Codes: A61B 2017/00907 for light
• CPC Class Codes: B01L 3/50 Containers for the purpose of retaining a material to be analysed, e.g. test tubes devices for taking samples of blood A61B5/15
• CPC Class Codes: G01N 23/04 and forming images of the material
• CPC Class Codes: Y10S 436/813 Cancer

Abstract

A tissue analysis device includes first and second plates which are rigid and radiographically transparent, at least one of the plates defining a plurality of pinholes arranged in an evenly spaced pattern to form a rectangular grid, with at least one of the plates including coordinate markings which can be seen both optically and radiographically to create a rectangular coordinate system for defining each section of the grid.

Claims

1. A tissue analysis device, comprising:

first and second plates, made of a material that is rigid and radiographically transparent;

at least one of said plates defining a plurality of pinholes arranged in an evenly-spaced pattern to form a rectangular grid system;

at least one of said plates including coordinate markings which are viewable both optically and radiographically to create a rectangular coordinate system for defining each segment of said grid system; and

clamping means for clamping together said first and second plates, including means for compressing an excised tissue specimen disposed therebetween, wherein said clamping means permits said clamped-together first and second plates to readily be moved into and out of an x-ray machine and onto a lab table.

2. A tissue analysis device as recited in claim 1, wherein said first plate includes said plurality of pinholes and is also optically transparent.

3. A tissue analysis device as recited in claim 2, wherein the first plate also includes the coordinate markings.

4. A tissue analysis device as recited in claim 1 or 3, wherein said coordinate markings are located along central vertical and horizontal axes of at least one plate.

5. A tissue analysis device as recited in claim 4, wherein the coordinate markings along one axis are numbers and the coordinate markings along the other axis are letters, so that each segment of the plate is defined by a unique letter and number combination.

6. A tissue analysis device as recited in claim 5, wherein said plurality of pinholes are spaced approximately two centimeters apart.

7. A tissue analysis device as recited in claim 4, wherein each of said first and second plates defines at least three fastener holes, so that corresponding fastener holes in said first and second plates are aligned to receive a fastener for clamping a tissue sample between said plates.

8. A tissue analysis device as recited in claim 7, and further comprising at least three bolts which are received in said fastener holes with a fairly close tolerance fit.

9. A tissue analysis device as recited in claim 1, wherein said coordinate markings are engraved on one of the plates.

10. A tissue analysis device, comprising:

first and second plates, made of a material that is rigid and radiographically transparent;

said first plate defining a plurality of pinholes arranged in an evenly-spaced pattern with respect to perpendicular axes to form a grid;

at least one of said plates being visually transparent;

said first plate defining at least three fastener holes, and said second plate defining at least three corresponding fastener holes, whereby said first and second plates may be clamped together with a tissue sample therebetween by means of fasteners passing through the aligned fastener holes in said first and second plates.

11. A tissue analysis device as recited in claim 10, further comprising at least three bolts which are received in said fastener holes for clamping together said first and second plates.

12. A tissue analysis device as recited in claim 10, wherein one of said plates includes coordinate markings along central vertical and horizontal axes, said coordinate markings being located between pinholes and being visible both optically and radiographically.

13. A tissue analysis device, comprising:

first and second plates, having substantially the same size and shape and being made of a material that is rigid and radiographically transparent;

at least one of said plates defining a plurality of pinholes arranged in an evenly-spaced pattern to form a rectangular grid system;

at least one of said plates including coordinate markings which are viewable both optically and radiographically to create a rectangular coordinate system for defining each location in said grid system; and

clamping means for clamping together said first and second plates including means for compressing an excised tissue specimen between them, wherein said clamping means permits the clamped-together plates to readily be moved into and out of an x-ray machine and onto a lab table.

14. A tissue analysis device as recited in claim 13, wherein said coordinate markings are formed by etching one of said plates, so that even portions of the tissue specimen behind the coordinate markings can be viewed both optically and radiographically.