Automatic fluid sedimentation rate measurement apparatus and method
First Claim
1. A sedimentation rate measurement apparatus for measuring a sedimentation rate of a fluid in a specimen tube, said apparatus comprising:
- a controllable specimen device member; and
data processor means operatively coupled to said specimen device member (i) for receiving sedimentation measurements produced by said sedimentation device member, (ii) for controlling said specimen device member and (iii) for generating sedimentation rate data of said fluid, wherein said specimen device member includes;
(1) light source means for illuminating said fluid,(2) light sensing means for responding to light transmitted from said light source means through said fluid and periodically producing sedimentation measurements for determining a sedimentation rate of said fluid, and(3) tube holder means including a member (211) disposed between the light source means and the light sensing means for holding a specimen tube in which said fluid is contained, and wherein said data processor means includes;
(a) data input means for entering specimen control data;
(b) data intereface means for receiving said sedimentation measurement data from said specimen device member;
(c) first memory means for storing said specimen control data and said sedimentation measurement data;
(d) microprocessor code means including microprocessor code for controlling operation of said specimen device member;
(e) second memory means for storing said microprocessor code;
(f) microprocessor means for performing calculations and analyses on said sedimentation measurement data and specimen control data in a manner computationally determined by said microprocessor code means; and
(g) data output means for producing results of said calculations and analyses.
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Accused Products
Abstract
An apparatus and method for automatically measuring and recording erythrocyte sedimentation rates (ESR) of blood samples according to the Westergren method includes a controllable specimen device member which measures sedimentation data of blood samples, and a data processor which controls the specimen device analyzes the sedimentation data and reports the results of its analyses. The specimen device is equipped with a controllable camera which measures the opacity of light passing through a specimen being analyzed. The camera has a high dynamic range, meaning that it is sensitive over a blood spectrum of light intensities, so that it guarantees an accurate reading even when the blood sample is hemolyzed or has turbid plasma. The apparatus makes an initial sedimentation height measurement on a specimen sample, and after a given amount of time makes a final sedimentation height measurement on that specimen. By comparing the initial and final sedimentation height measurements over a elapsed sedimentation time, the data processor calculates the sedimentation rate of the sample.
50 Citations
14 Claims
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1. A sedimentation rate measurement apparatus for measuring a sedimentation rate of a fluid in a specimen tube, said apparatus comprising:
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a controllable specimen device member; and data processor means operatively coupled to said specimen device member (i) for receiving sedimentation measurements produced by said sedimentation device member, (ii) for controlling said specimen device member and (iii) for generating sedimentation rate data of said fluid, wherein said specimen device member includes; (1) light source means for illuminating said fluid, (2) light sensing means for responding to light transmitted from said light source means through said fluid and periodically producing sedimentation measurements for determining a sedimentation rate of said fluid, and (3) tube holder means including a member (211) disposed between the light source means and the light sensing means for holding a specimen tube in which said fluid is contained, and wherein said data processor means includes; (a) data input means for entering specimen control data; (b) data intereface means for receiving said sedimentation measurement data from said specimen device member; (c) first memory means for storing said specimen control data and said sedimentation measurement data; (d) microprocessor code means including microprocessor code for controlling operation of said specimen device member; (e) second memory means for storing said microprocessor code; (f) microprocessor means for performing calculations and analyses on said sedimentation measurement data and specimen control data in a manner computationally determined by said microprocessor code means; and (g) data output means for producing results of said calculations and analyses. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A sedimentation rate measurement apparatus for measuring a sedimentation rate of a fluid in a specimen tube, said apparatus comprising:
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a controllable specimen device member; and data processor means operatively coupled to said specimen device member (i) for receiving sedimentation measurements produced by said sedimentation device member, (ii) for controlling said specimen device member and (iii) for generating sedimentation rate data of said fluid, wherein said specimen device member includes; (1) light source means for illuminating said fluid, (2) light sensing means for responding to light transmitted from said light source means through said fluid and periodically producing sedimentation measurements for determining a sedimentation rate of said fluid, and (3) tube holder means including a member (211) disposed between the light source means and the light sensing means for holding a specimen tube in which said fluid is contained, and wherein said specimen device member further comprises; covering means for enclosing said specimen device member; light shield means for confining said light source means within said cover means and for excluding ambient laboratory light; and aperture means disposed between said light source means and said light sensing means for allowing said light to escape said shield means in a pattern directed toward said light sensing means.
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10. A method of obtaining sedimentation rate data of a fluid, said method comprising the steps of:
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(a) providing a specimen device member, said specimen device member having, tube holder means for holding a specimen tube, light source means disposed within the tube holder means for illuminating said specimen tube, light sensing means for responding to light transmitted from said light source means through said specimen tube and for producing sedimentation measurements according to opacity of said transmitted light and means disposed in proximity with said light source means and with said light sensing means for impeding the transmission, beyond the specimen device member, of light that emanates from the light source means and for impeding the transmission, into the specimen device member, of ambient light; (b) operatively coupling a data processor member to said specimen device member; and (c) generating sedimentation rate data from said sedimentation measurements produced by said light sensing means, said method further comprising the steps of; providing said tube holder means as a rotatable cylindrical drum member; operatively coupling a drum motor means to said drum member for rotating said drum member; attaching a plurality of tube holder members about a circumference of said drum member; providing said drum member with revolution sensor means for repeatedly sensing a completed revolution of said drum member and for providing a signal indicating each completed revolution; and providing said drum member with a tube holder sensor means for repeatedly sensing substantial alignment of each tube holder member of said plurality of tube holder members with said light sensing means, and for providing a signal indicating each substantial alignment, and wherein said data processor means includes; (d) data input means for entering specimen control data; (e) data interface means for receiving said sedimentation measurement data from said specimen device means; (f) first memory means for storing said specimen control data and said sedimentation measurement data; (g) microprocessor code means for controlling operation of said specimen device member; (h) second memory means for storing said microprocessor code means; (i) microprocessor means for performing calculations and analyses on said sedimentation measurement data and specimen control data in a manner computationally determined by said microprocessor code means; and (j) data output means for producing results of said calculations and analyses. - View Dependent Claims (11, 12, 13, 14)
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Specification