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Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes

  • US 5,004,565 A
  • Filed: 07/27/1988
  • Issued: 04/02/1991
  • Est. Priority Date: 07/17/1986
  • Status: Expired due to Term
First Claim
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1. A composition which generates light upon triggering which comprises in admixture:

  • (a) a fluorescent compound; and

    (b) a stable 1,2-dioxetane of the formula;

    ##STR32## wherein ArOX represents an aryl group substituted with an X-oxy group which forms an unstable oxide intermediate 1,2-dioxetane compound when triggered to remove X by an activating agent so that the unstable 1,2-dioxetane compound decomposes and releases electronic energy to form light and two carbonyl containing compounds of the formula;

    ##STR33## wherein X is a chemically labile group which is removed by the activating agent to form the unstable oxide intermediate 1,2-dioxetane and wherein A are passive organic groups which allow the light to be produced wherein the stable 1,2-dioxetane is decomposed with the activating agent wherein the dioxetane and the fluorescent compound are provided in a closely spaced relationship in the presence of a surfactant, micelle, liposome, reversed micelle, microemulsion, film, including a monolayer, or polymer and wherein the fluorescent compound accepts the electronic energy generated upon decomposition of the unstable oxide intermediate and produces a more intense light than is produced by the triggering of the dioxetane alone.

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