Capillary flow device
First Claim
1. A control device capable of detecting depletion of a particle-containing fluid from a sample reservoir in a device comprising a sample reservoir and a capillary exiting said reservoir, which comprises:
- a light source located so as to impinge on said fluid in said reservoir;
a light detector located in close proximity to said capillary so as to collect light which is reflected by said particles into said capillary and thereafter further reflected by said particles so as to pass out through the walls of said capillary;
a signal generator operably attached to said light source, wherein a detectable signal is imposed on the output of said light source; and
a filter operably attached to the output of said light detector, wherein said detectable signal is isolated from other light sources which may impinge upon said light detector.
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Accused Products
Abstract
Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
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Citations
5 Claims
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1. A control device capable of detecting depletion of a particle-containing fluid from a sample reservoir in a device comprising a sample reservoir and a capillary exiting said reservoir, which comprises:
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a light source located so as to impinge on said fluid in said reservoir; a light detector located in close proximity to said capillary so as to collect light which is reflected by said particles into said capillary and thereafter further reflected by said particles so as to pass out through the walls of said capillary; a signal generator operably attached to said light source, wherein a detectable signal is imposed on the output of said light source; and a filter operably attached to the output of said light detector, wherein said detectable signal is isolated from other light sources which may impinge upon said light detector. - View Dependent Claims (2, 3, 4, 5)
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Specification