Muscle-powered cardiac assist device

• US 5,007,927 A
• Filed: 10/24/1989
• Issued: 04/16/1991
• Est. Priority Date: 10/24/1989
• Status: Expired due to Fees

• Current Assignee: Purdue Research Foundation (The Trustees of Purdue University (d/b/a Purdue University))
• Original Assignee: Purdue Research Foundation (The Trustees of Purdue University (d/b/a Purdue University))
• Inventors: Wessale, Jerry L., Badylak, Stephen F., Geddes, Leslie A.
• Primary Examiner(s): Shay, Randy Citrin
• Application Number:
  US07/426,301
• Time in Patent Office: 539 Days
• Field of Search: 623/3, 600/16, 600/17, 600/18
• US Class Current: 623/3.12
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/152 branching on and drawing blood from a blood vessel
• CPC Class Codes: A61M 60/274 the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
• CPC Class Codes: A61M 60/438 the force acting on the blood contacting member being mechanical
• CPC Class Codes: A61M 60/515 Regulation using real-time patient data
• CPC Class Codes: A61M 60/837 Aspects of flexible displacement members, e.g. shapes or materials
• CPC Class Codes: A61M 60/878 Electrical connections within the patient's body
• CPC Class Codes: A61M 60/882 Devices powered by the patient, e.g. skeletal muscle powered devices
• CPC Class Codes: A61M 60/892 Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/896 having flexible or resilient parts, e.g. flap valves

Abstract

A method and apparatus is provided for enhancing blood circulation, and thereby reducing fatigue, in a skeletal muscle used for powering a cardiac assist device wherein the muscle is positioned to compress a blood reservoir in response to muscle contracting stimuli. Enhanced perfusion of the skeletal muscle is achieved by delaying blood flow into the reservoir for a period of time following each muscle contraction.

Claims

1. An apparatus for enhancing circulation of blood in skeletal muscle in use for powering a cardiac assist device including a blood reservoir in fluid communication with a patient'"'"'s circulatory system, wherein said skeletal muscle is positioned to compress the blood reservoir in response to a muscle contracting stimulus from a pulse generator said circulation enhancing apparatus comprising

a valve positioned to control blood flow from the patient'"'"'s circulatory system into the blood reservoir, and

means for activating the valve in a timed relationship to the muscle contracting stimulus.

2. The apparatus of claim 1 wherein the valve activating means is a programmable signal generating circuit in the pulse generator.

3. The apparatus of claim 1, wherein the blood reservoir has a blood outlet conduit and a blood inlet conduit each in fluid communication with the patient'"'"'s circulatory system, and wherein the valve is positioned in the blood inlet conduit and a unidirectional valve is positioned in the blood outlet conduit to prevent blood flow from the patient'"'"'s circulatory system into the blood reservoir through said blood outlet conduit.

4. The apparatus of claim 1 wherein the valve is biased in a closed position.

5. The apparatus of claim 4 wherein the valve is electrically activated by an electric pulse generator in an adjustable timed relationship to the muscle contracting stimulus.

6. The apparatus of claim 1 further comprising means for sensing heart activity wherein the muscle contracting stimulus from the pulse generator is applied to the skeletal muscle in a timed relationship to sensed heart activity.

7. An apparatus for enhancing circulation of blood through skeletal muscle in use for powering a cardiac assist device for providing blood pumping action to supplement heart blood pumping action, wherein said skeletal muscle is positioned to compress a blood reservoir in response to a muscle contracting stimulus, the blood reservoir in fluid communication with a patient'"'"'s circulatory system, said apparatus comprising,

a blood outlet conduit and a blood inlet conduit, each in fluid communication with the patient'"'"'s circulatory system and the blood reservoir,

an unidirectional flow valve in the blood outlet conduit to prevent blood flow from the patient'"'"'s circulatory system into the blood reservoir through the blood outlet,

an electrically activated valve positioned in the blood inlet conduit to control blood flow from the patient'"'"'s circulatory system into the blood reservoir, and

means for activating the electrically activated valve in a timed relationship to the muscle contracting stimulus.

8. A method for enhancing circulation of blood through skeletal muscle used for powering a cardiac assist device including a blood reservoir in fluid communication with a patient'"'"'s circulatory system in which device said skeletal muscle is positioned to compress the blood reservoir in response to muscle contracting stimuli, said method comprising the step of delaying blood flow into the blood reservoir for a predetermined period of time following each muscle contracting stimulus.