Method and apparatus for detection of posterior ischemia

• US 5,010,888 A
• Filed: 11/04/1988
• Issued: 04/30/1991
• Est. Priority Date: 03/25/1988
• Status: Expired due to Fees

• Current Assignee: Arzco Medical Electronics Incorporated
• Original Assignee: Arzco Medical Electronics Incorporated
• Inventors: Jadvar, Hossein, Arzbaecher, Robert C.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): Manuel, George
• Application Number:
  US07/267,459
• Time in Patent Office: 907 Days
• Field of Search: 128/695, 128/696, 128/697, 128/699, 128/700, 128/702, 128/703, 128/704, 128/705, 128/706, 128/707, 128/419 PG, 128/419 D, 128/787
• US Class Current: 600/509
• CPC Class Codes: A61B 5/285 Endotracheal, oesophageal or gastric probes
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 5/7217 of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371

Abstract

An apparatus for automatically detecting a posterior ischemia includes a multi-element esophageal electrode coupled to an artifact suppressing circuit and a cardiac stimulator. Output from the artifact suppressing circuit, the detected QRS wave, is processed in analog and digital filters. The processed signal is analyzed to automatically determine the presence or absence of the posterior ischemia.

Claims

1. A method of automatically detecting a selected posterior heart condition in a person comprising:

positioning a sensing electrode adjacent a posterior surface of the person'"'"'s heart;

electrically stressing the heart;

detecting electrical signals from the electrode that have been generated in response to stressing the heart irrespective of the presence of stressing induced artifacts;

filtering the detected signals;

automatically locating a local maximum of the filtered signals;

automatically measuring selected regions of the filtered signals adjacent the local maximum; and

generating an indicium indicative of the presence or absence of the selected posterior heart condition.

2. A method as in claim 1 with the step of stressing including:

stressing the heart in response to exercise by the person.

3. A method as in claim 1 including:

positioning at least one stressing electrode adjacent the posterior surface of the heart.

4. A method as in claim 3 including:

providing a selected electrical signal to the stressing electrode thereby stressing the heart in response thereto while suppressing artifacts generated by the selected electrical signal.

5. A method as in claim 3 with said measuring step including:

automatically determining the corresponding values of the filtered signals adjacent the local maximum; and

comparing the corresponding values.

6. An apparatus for automatically detecting a selected posterior heart condition in a person comprising:

electrode means, positionable in the person'"'"'s esophagus adjacent a posterior surface of the person'"'"'s heart, for sensing electrical signals generated by the heart;

means for electrically stressing the heart;

means for detecting electrical signals from said electrode means that have been generated in response to stressing the heart;

means for recording the detected signals essentially simultaneously with said stressing;

means for processing the detected, recorded, signals;

means for automatically measuring selected regions of the processed signals; and

means for generating an indicium indicative of the presence or absence of the selected posterior heart condition.

7. An apparatus as in claim 6 including:

stressing electrode means positionable adjacent the posterior surface of the heart.

8. An apparatus as in claim 7 including:

means for providing a selected electrical signal to said stressing electrode means so as to stress the heart in response thereto.

9. An apparatus as in claim 6 including:

means for filtering the detected electrical signals prior to processing same.

10. An apparatus as in claim 6 with said measuring means including means for measuring selected portions of the processed signals corresponding to an ST segment thereof.

11. An apparatus as in claim 6 with said measuring means including:

means for locating a first region of the processed signal;

means for locating second and third regions, displaced from the first region;

means for determining the corresponding values of a processed signal at the second and third regions; and

means for comparing the corresponding values.

12. An apparatus as in claim 11 with said first region locating means including means for identifying a local maximum value of said detected electrical signals.

13. An apparatus as in claim 12 including means for locating said second and third regions on the order of 60 multi-seconds prior to said local maximum and 80 milli-seconds after same.

14. An apparatus as in claim 6 including means for suppressing selected stressing related electrical noise signals.

15. An apparatus as in claim 6 with said electrode means including a swallowable body portion.

16. A method of non-invasively and automatically detecting posterior ischemia of a heart comprising:

positioning a sensing electrode adjacent a posterior surface of the person'"'"'s heart;

stressing the heart;

detecting electrical signals from the electrode that have been generated in response to stressing the heart;

processing the detected signals;

automatically measuring selected regions of the processed signals; and

generating an indicium indicative of the presence or absence of the posterior ischemia.

17. A method as in claim 16 including in the stressing step:

positioning at least one stressing electrode adjacent the posterior surface of the heart.

18. A method as in claim 17 including:

providing a selected electrical signal to the stressing electrode thereby stressing the heart in response thereto.

19. A method as in claim 16 including:

filtering the detected electrical signals prior to processing same.

20. A method as in claim 16 with said measuring step including measuring selected portions of the processed signals corresponding to an ST segment.

21. A method as in claim 20 with said measuring step including:

locating a first region of the processed signal;

locating second and third regions, displaced from the first region;

determining the corresponding values of the processed signal at the second and third regions; and

comparing the corresponding valves.

22. A method as in claim 21 with said first region corresponding to a local maximum of the processed signal.

23. A method as in claim 22 with the processed signal corresponding to the R wave from the person'"'"'s heart and the local maximum corresponding to the R pulse maximum.

24. A method as in claim 22 including locating second and third regions displaced in time on the order of 60 milli-seconds and 80 milli-seconds from the local maximum.

25. A method as in claim 20 including forming a difference between selected measured valves.

26. A method of detecting posterior ischemia of a heart comprising:

positioning a multi-element electrode adjacent a posterior surface of the heart;

supplying a selected heart stressing electrical signal to at least selected elements of the electrode;

suppressing artifacts generated by the stressing electrical signal;

detecting stress generated electrical signals from at least one selected element of the electrode;

processing the detected signals;

automatically measuring selected regions of the processed signals; and

generating an indicium indicative of the presence or absence of the posterior ischemia.

27. A method as in claim 26 with said processing step including analog filtering of the detected signals.

28. A method a sin claim 26 with said processing step including digital filtering of the detected signals.

29. A method as in claim 28 including means for detecting a local maximum of said processed signals.

30. A method as in claim 29 including digital means for determining values of said processed signals a selected interval prior to said local maximum and a selected interval subsequent to said local maximum.

31. A method as in claim 30 including processing a plurality of values of the processed signals.

32. A method as in claim 30 including determining a plurality of slopes of processed signals.

33. A method as in claim 26 with the processing step including analog filtering of the detected signals followed by digital filtering thereof.

34. A method as in claim 33 with the digital filtering including inverse filtering of the analog filtered signal.

35. An apparatus for automatically detecting posterior ischemia in the heart of a person comprising:

multi-element electrode means, positionable in the person'"'"'s esophagus, for receiving and transmitting electrical signals;

means, coupled to said electrode means, for supplying selected heart stressing electrical signals to selected elements of said electrode means;

means, coupled to said processing means, for blocking selected electrical signals induced by said heart stressing electrical signals;

means, coupled to said electrode means, for detecting stress generated electrical signals from at least one selected element of said electrode means, concurrent with said stressing;

means for processing the detected signals and generating processed signals corresponding thereto;

means for automatically measuring selected regions of the processed signals; and

means for generating an indicium indicative of the presence or absence of the posterior ischemia.

36. An apparatus as in claim 35 including means for filtering said stress generated electrical signals.

37. An apparatus as in claim 36 with said filtering means including an analog filter.

38. An apparatus as in claim 36 with said filtering means including a digital filter.

39. An apparatus as in claim 36 with said filtering means including an analog filter followed by an inverse digital filter.

40. An apparatus as in claim 35 with said processing means including stored program computing means.

41. A method of detecting a selected heart condition using esophageal pacing comprising:

supplying electrical pacing signals from an esophageal site adjacent a posterior surface of the heart;

sensing heart generated, pacing related, electrical signals irrespective of any stressing induced artifacts;

simultaneously recording the pacing signals exclusive of any induced artifacts; and

automatically analyzing the recorded pacing signals;

an analysis system for analyzing said recorded signals.

42. An apparatus for detection of a selected posterior heart condition from an esophageal site comprising:

an apparatus, positionable in the esophagus, for generating pacing electrical signals, said apparatus including a conductor for detecting pacing induced, heart generated electrical signals;

a suppression circuit, coupled to said apparatus, for suppressing electrical artifacts induced by said pacing signals;

a recording system for recording said pacing induced signals while generating said pacing signals; and

an analysis system for analyzing said recorded signals.