Thrombus extraction system

• US 5,011,488 A
• Filed: 08/20/1990
• Issued: 04/30/1991
• Est. Priority Date: 12/07/1988
• Status: Expired due to Term

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Robert Ginsburg
• Inventors: Ginsburg, Robert
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): Lewis, William W.
• Application Number:
  US07/569,751
• Time in Patent Office: 253 Days
• Field of Search: 604/22, 604/52, 604/53, 604/96, 604/97, 604/98, 604/99, 604/100, 604/101, 604/102, 604/103, 604/104, 604/159, 604/264, 604/281, 606/159, 606/198, 606/200
• US Class Current: 606/159
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22032 having inflatable gripping elements balloon catheters A61M25/10
• CPC Class Codes: A61B 2017/22051 with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation A61B2017/22048, A61B2017/3486 take precedence
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61M 1/84 Drainage tubes; Aspiration tips for negative pressure wound therapy A61M1/90; for surgical cutting instruments A61B17/32
• CPC Class Codes: A61M 2025/109 having balloons for removing solid matters, e.g. by grasping or scraping plaque, thrombus or other matters that obstruct the flow
• CPC Class Codes: A61M 25/0074 Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable

Abstract

A vascular catheter system comprises an outer flexible tube, an inner flexible tube disposed in the lumen of the outer flexible tube, and an expandable body mounted at the distal end of the third flexible tube disposed in the lumen of the inner flexible tube. The catheter system is suitable for percutaneous introduction to a blood vessel where the distal end may be located proximate a region of clot or thrombus. By extending the expandable body through the region of clot or thrombus, the obstructing material may be dislodged from the blood vessel wall and drawn toward the open distal end of the inner tube. The inner tube includes an expandable tip which will open to extend substantially across the blood vessel. In this way, the expandable tip will be positioned to collect all of the dislodged clot and thrombus. By withdrawing both the inner tube and the expandable body back into the outer flexible tube, the catheter system may be withdrawn from the patient without appreciable loss of the clot or thrombus.

Claims

1. A catheter system comprising:

an outer flexible tube having proximal and distal ends and a central lumen extending therethrough; and

an inner flexible tube having proximal and distal ends and a central lumen extending therethrough, said inner flexible tube having an open distal tip which assumes an expanded configuration when unconstrained and being reciprocatably disposed in the central lumen of the outer flexible tube, wherein the length of the inner flexible tube is sufficient to extend beyond the proximal end of the central lumen in the outer flexible tube even when the open distal tip extends beyond the distal end of the outer flexible tube, whereby the tip is expended when extended beyond the distal end of the outer tube and collapsed when drawn within the distal end of the outer tube.

2. A catheter system as in claim 1, further comprising:

means for drawing clot or thrombus into the tip of the inner flexible tube while said tip is in its expanded configuration.

3. A catheter system comprising:

an outer flexible tube having proximal and distal ends and a central lumen extending therethrough;

an inner flexible tube having proximal and distal ends and a central lumen extending therethrough, said inner flexible tube having an open distal tip which assumes an expanded configuration when unconstrained and being reciprocatably disposed in the central lumen of the outer flexible tube, whereby the tip is expanded when extended beyond the distal end of the outer tube and collapsed when drawn within the distal end of the outer tube; and

an inflatable balloon at a distal end of a flexible inflation tube disposed within the central lumen of the inner flexible tube for drawing clot or thrombus into the tip of the inner flexible tube while said tip is in its expanded configuration.

4. A catheter system as in claim 3, wherein the shape of the inflated balloon is complementary to that of the expanded tip.

5. A catheter system as in claim 4, wherein the complementary shape is substantially conical.

6. A catheter system comprising:

an outer flexible tube having proximal and distal ends and a central lumen extending therethrough;

an inner flexible tube having proximal and distal ends and a central lumen extending therethrough, said inner flexible tube having an open distal tip which assumes an expanded configuration when unconstrained and being reciprocatingly disposed in the central lumen of the outer flexible tube, whereby the tip is expended when extended beyond the distal end of the outer tube and collapsed when drawn within the distal end of the outer tube; and

an expandable coil secured to a distal end of a third flexible tube disposed within the central lumen of the inner flexible tube for drawing clot or thrombus into the tip of the inner flexible tube while said tip is in its expanded configuration.

7. A catheter system comprising:

an inner flexible tube having proximal and distal ends and a central lumen extending therethrough;

means mounted on the distal end of said inner flexible tube for capturing and securing thrombus material therein; and

means comprising an expandable body mounted on a third tube reciprocatably disposed within the central lumen of the inner flexible tube, said expandable body being disposed at the distal end of said inner flexible tube for drawing clot or thrombotic material from a blood vessel into the means for capturing and securing, whereby clot and thrombotic material can be removed by drawing said material into the mans for capturing and securing and withdrawing said inner flexible tube from the blood vessel.

8. A catheter system as in claim 7, wherein the means for capturing and securing clot or thrombus comprises an open tip at the distal end of the flexible tube, said distal tip being convertible between an expanded configuration which captures clot or thrombus and a collapsed configuration which secures the clot or thrombus.

9. A catheter system as in claim 8, wherein the means for capturing and securing clot or thrombus further comprises an outer flexible tube circumscribing the inner flexible tube, whereby the open distal tip is expanded by extending said tip beyond the outer flexible tube and is collapsed by retracting said tip within the outer flexible tube.

10. A catheter system as in claim 7, wherein the expandable body is an inflation balloon.

11. A catheter system comprising:

an inner flexible tube having proximal and distal ends;

an outer flexible tube circumscribing the inner flexible tube having proximal and distal ends;

means mounted on the distal end of said inner flexible tube for capturing and securing thrombus material therein; and

an expandable coil mounted at the distal end of a third flexible tube for drawing clot or thrombus into the means for capturing and securing, said third flexible tube being reciprocatingly disposed within a central lumen of the inner flexible tube.

12. A method for removing clot or thrombus from a blood vessel, said method comprising:

percutaneously introducing a catheter having an open distal end into the blood vessel so that said distal end of the catheter is located proximate the region of clot or thrombus;

extending an expandable body from the distal end of the catheter through the region of clot or thrombus;

expanding the expandable body so that its periphery contacts the inside wall of the blood vessel;

expanding the open distal end of the catheter; and

drawing the expandable body in its expanded configuration back to the expanded distal end of the catheter, whereby the thrombus is translated back to said distal end; and

capturing the thrombus in the distal end of the catheter.

13. A method as in claim 12, wherein the expandable body is a balloon which is expanded by inflation.

14. A method as in claim 12, wherein the expandable body is a coil which is expanded by compression.

15. A method as in claim 12, further comprising aspirating the catheter while the clot or thrombus is being drawn in by the expandable body.

16. A method as in claim 12, wherein the expandable body is drawn into the expanded distal end of the catheter to complete capture of the clot or thrombus.

17. A method for removing clots or thrombus from a blood vessel, said method comprising:

percutaneously introducing a catheter having an open distal end into the blood vessel so that said distal end of the catheter is located proximate the region of clot or thrombus;

extending an expandable body from the distal end of the catheter through the region of clot or thrombus;

expanding the expandable body so that its periphery contacts the inside wall of the blood vessel;

expanding the distal end of the catheter to facilitate capture of the clot or thrombus;

drawing the expandable body in its expanded configuration back to the expanded distal end of the catheter, whereby said thrombus is translated back to said distal end; and

simultaneously collapsing said expandable body and expandable distal end into an outer flexible tube to facilitate removal of the catheter with the clot or thrombus.

18. A method as in claim 17, further comprising aspirating the catheter while the clot or thrombus is being drawn in by the expandable body.