Rate responsive cardiac pacemaker

• US 5,014,704 A
• Filed: 04/27/1990
• Issued: 05/14/1991
• Est. Priority Date: 09/12/1986
• Status: Expired due to Term

• Current Assignee: Advanced Medical Optics Incorporated (Johnson & Johnson)
• Original Assignee: Intermedics Incorporated (Boston Scientific Corporation)
• Inventors: Alt, Eckhard
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): Manuel, George
• Application Number:
  US07/515,460
• Time in Patent Office: 382 Days
• Field of Search: 128/419 PG, 128/419 P
• US Class Current: 607/19
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

An implantable variable rate pacemaker adaptive to patient exercise includes a motion sensor for detecting physical activity of the patient and producing an electrical signal having an amplitude vlaue representative of the intensity of the physical activity. The electrical signal is selectively limited to appreciable amplitude values for detected physical activity which is related to true physical exercise by the patient, in contrast to activity related to internal and external disturbances on the patient. The pacemaker compares the amplitude values of the selectively limited electrical signal to successively higher programmed threshold values representative of successively greater workloads of physical exercise to adjust the pacing rate to a higher rate as each of the threshold values is exceeded. The motion sensor is an accelerometer implemented in a semiconductor device which converts mechaical movements to an electrical signal having an amplitude representative of the intensity of the mechanical movements, and is housed within and isolated from the pulse generator case of the pacemaker. The electrical signal is processed by a circuit integral with the semiconductor device which limits the signal amplitude to appreciable values in response to detected physical activity in a preselected frequency range.

Claims

1. An implantable variable rate pacemaker adaptive to patient exercise, comprising

means for detecting movements of the patient;

means discriminating between those of said detected movements which are indicative of physical exercise by the patient and those of said detected movements which are attributable to other than physical exercise for producing an electrical signal substantially limited to and representative of said detected movements indicative of physical exercise, with a variable amplitude-determined value related to the instantaneous level of physical exercise;

means responsive to said amplitude-determined value of said electrical signal for maintaining the rate of said pacemaker at a base rate corresponding to a predetermined resting rate at times when said amplitude-determined value is less than a preestablished threshold value representative of a first level of physical exercise and for increasing the rate of said pacemaker to a rate higher than said base rate consistent with said first level of exercise when said amplitude-determined value exceeds said threshold value; and

means further responsive to said threshold value having been exceeded by said amplitude-determined value for setting said threshold value as the new baseline and setting a new higher threshold value representative of a second level of physical exercise which when exceeded by said amplitude-determined value will increase the rate of said pacemaker to a still higher rate consistent with said second level of physical exercise.

2. The invention of claim 1, wherein said detecting means includes an accelerometer.

3. The invention of claim 2, wherein said accelerometer comprises a mechanoelectrical transducer for converting mechanical movements to an electrical signal having a variable amplitude value representative of the intensity of said mechanical movements.

4. The invention of claim 3, wherein said transducer comprises a semiconductor device.

5. The invention of claim 4, wherein said discriminating means includes an electrical circuit integral with said semiconductor device for processing said electrical signal to selectively limit said electrical signal to appreciable amplitude values in response to said mechanical movements in a preselected frequency range.

6. The invention of claim 3, wherein said discriminating means comprises a portion of said transducer configured to selectively limit said electrical signal of said transducer to appreciable amplitude values in response to frequencies of said mechanical movements lying in a preselected frequency range.

7. The invention of claim 2, wherein said discriminating means comprises a bandpass filter having a preselected frequency range, coupled to the output of said accelerometer.

8. A variable rate pacemaker responsive to patient exercise, comprising motion sensing means for detecting physical activity of the patient and producing an electrical signal having an amplitude value representative of the intensity of said physical activity, means for selectively limiting said electrical signal to appreciable amplitude values for said detected physical activity which is related to true physical exercise by the patient in contrast to said detected physical activity which is related to internal and external disturbances on the patient, and means for comparing the amplitude values of said selectively limited electrical signal to successively higher programmed threshold values representative of successively greater workloads of physical exercise to adjust the rate of said pacemaker to a higher rate as each of said threshold values in exceeded.

9. The invention of claim 8, wherein said comparing means includes means for initiating a programmed transition from the rate to which said pacemaker is adjusted based on the last of said threshold values exceeded by the amplitude values of said selectively limited electrical signal to a preset base rate when the amplitude value of the signal drops to a predetermined level indicative of an absence of true physical exercise.

10. The invention of claim 8, further including means for establishing a new higher threshold value against which the amplitude value of the signal is compared when the last threshold value used for comparison has been exceeded, whereby said last threshold value constitutes a new exercise baseline to prevent false triggerings of said pacemaker to higher rates as said exercise baseline is exceeded without exceeding said new higher threshold.

11. A pacemaker having a variable rate adaptive to physical exercise by the patient, comprising

means responsive to movements of the pacemaker for distinguishing between movements of a first type associated with physical exercise and movements of a second type associated with factors other than physical exercise,

means for establishing a first threshold level representing a magnitude of said distinguished movements of said first type demanding an initial increase in the pacing rate generated by said pacemaker,

means responsive to the distinguished movements of said first type and to the magnitude thereof for selectively setting successively higher threshold levels as previously set ones of said threshold levels are exceeded by said distinguished movements of said first type, and

means responsive to each of said threshold levels being exceeded for increasing the rate of said pacemaker by a respective predetermined amount and thereupon establishing the latest exceeded threshold level as a new baseline value above which is indicative of increased physical exercise and below which is indicative of not more than sustained physical exercise.

12. The invention of claim 11, wherein said distinguishing means includes an accelerometer.

13. The invention of claim 12, wherein said distinguishing means further includes bandpass filter means having a preselected frequency range for circumscribing the output of said accelerometer.

14. The invention of claim 12, wherein said pacemaker includes a housing, and wherein said accelerometer is situated within and isolated from said housing.

15. The invention of claim 14, wherein said accelerometer comprises a semiconductor device.

16. The invention of claim 15, wherein said accelerometer generates an electrical signal representative of the magnitude of movements of said first type, and wherein said distinguishing means further includes an electrical circuit integral with said semiconductor device for processing said electrical signal generated by said accelerometer.

17. A process for controlling the heart rate of a patient by artificial stimulation of the heart at a variable rate according to patient exercise, comprising the steps of detecting movements of the patient;

discriminating between said detected movements indicative of physical exercise by the patient and said detected movements indicative of non-exercise and producing an electrical signal substantially limited to and representative of said detected movements indicative of physical exercise, with a variable amplitude-determined value related to the instantaneous level of physical exercise;

maintaining said stimulation rate at a base rate corresponding to a predetermined resting rate at times when said amplitude-determined value of said electrical signal is less than a preestablished threshold value representative of a first level of physical exercise and increasing said stimulation rate to a rate higher than said base rate consistent with said first level of exercise when said amplitude-determined value exceeds said threshold value;

setting said threshold value exceeded by said amplitude-determined value as the new baseline and setting a new higher threshold value representative of a second level of physical exercise; and

increasing said stimulation rate to a still higher rate consistent with said second level of physical exercise when said new threshold value is exceeded by said amplitude-determined value.

18. Method of pacing a patient'"'"'s heart at a variable rate adaptive to physical exercise by the patient, comprising the steps of distinguishing between movements by the patient of a first type associated with physical exercise and movements by the patient of a second type associated with factors other than physical exercise, establishing a first threshold level representing a magnitude of patient movements of said first type demanding an initial increase in said pacing rate, responding to distinguished movements of said first type and to the magnitude thereof by selectively setting successively higher threshold levels are previously set ones of said threshold levels are exceeded by said distinguished movements of said first type, and increasing said pacing rate by a respective predetermined amount as each of said threshold levels is successively exceeded and thereupon establishing the latest exceeded threshold level as a new baseline value above which is indicative of increased physical exercise and below which is indicative of not more than sustained physical exercise.