Closure cap for dialyzers

• US 5,015,374 A
• Filed: 07/27/1989
• Issued: 05/14/1991
• Est. Priority Date: 07/28/1988
• Status: Expired due to Term

• Current Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Inventors: Schnur, Jurgen, Selzer, Dieter, Weber, Wolfram, Mathieu, Bernd, Rinck, Michael
• Primary Examiner(s): Jones, W. Gary
• Application Number:
  US07/386,284
• Time in Patent Office: 656 Days
• Field of Search: 210/232, 210/321.71, 210/321.72, 210/321.73, 210/321.74, 210/321.75, 210/321.76, 210/321.77, 210/321.78, 210/321.79, 210/321.8 , 210/321.81, 210/541, 210/321.69, 285/319, 285/320, 285/396, 285/399, 285/403, 285/417, 285/901, 285/921
• US Class Current: 210/232
• CPC Class Codes: A61M 1/168 Sterilisation or cleaning before or after use
• CPC Class Codes: A61M 1/1682 both machine and membrane module, i.e. also the module blood side
• CPC Class Codes: A61M 39/20 Closure caps or plugs for connectors or open ends of tubes
• CPC Class Codes: B01D 2321/16 Use of chemical agents
• CPC Class Codes: B01D 61/30 Accessories; Auxiliary operation
• CPC Class Codes: B01D 65/022 Membrane sterilisation
• CPC Class Codes: Y10S 285/921 Snap-fit

Abstract

The invention relates to a closure cap (1) for dialyzers which is suitable for a so-called in-line sterilization. For this purpose the closure cap (1) comprises two cap parts (2, 3) of which the first cap part (2) is adapted to be mounted on a dialyzer flange (4) while the second cap part (3) is arranged movably in a receiving compartment (5) of the first cap part (2) between an open position and a closure position. In an open position passage of a sterilization medium is possible so that all the parts, sealing and guide surfaces can be reliably sterilized. In the closure position the second cap part (3) is pushed into a sealing position within the first cap part (2) so that contamination of the dialyzer after removal from the sterilization apparatus can be prevented with certainty.

Claims

1. In a closure cap for dialyzers comprising first and second cap parts (2, 3), of which the first cap part (2) comprises means for attaching the first cap part to a dialyzer flange (4) while the second cap part (3) is movable between an open position in which the passage of a sterilization medium takes place and a closure position, the improvement wherein:

the first cap part (2) comprises a connection portion (16) having means (22,

     60) for sealing the dialyzer flange (4) in the assembled state in a sterile manner and a first portion (6) which is adapted to be brought into flow connection with an in-line sterilization means.

2. The improvement according to claim 1, characterized in that the first cap part (2) is made substantially tubular and comprises at one side a receiving compartment (5) for the second cap part (3) which is arranged in the first portion (6).

3. The improvement according to claim 2, characterized in that the receiving compartment (5) comprises first, second and third consecutive subchambers (7, 8, 9) which are arranged from an open end side (10) with decreasing diameters up to an end region (11) of the first portion (6) opposite the end side (10) in said portion.

4. The improvement according to claim 3, characterized in that between the first subchamber (7) with the greatest diameter and the second subchamber (8) a step (12) extending inwardly substantially perpendicularly to the longitudinal axis of the first cap part (2) is arranged.

5. The improvement according to claim 3, characterized in that the second subchamber (8) and the third subchamber (9) of smallest diameter are connected together via a conical intermediate portion (13).

6. The improvement according to claim 3, characterized in that an inner surface (14) of the fist subchamber (7) forms a guide and retaining surface for the second cap part (3).

7. The improvement according to claim 3, characterized in that an inner surface (15) of the third subchamber (9) also forms a guide surface for the second cap part (3).

8. The improvement according to claim 2, characterized in that the first cap part (2) comprises an elastic sealing means (60).

9. The improvement according to claim 8, characterized in that the elastic sealing means is formed as O ring (60) which is arranged in an annularly encircling inner sealing groove (59) and in the assembled state cooperates with a dialyzer collar (53) of the dialyzer flange (4) for generating the sealing effect.

10. The improvement according to claim 8, characterized in that in the receiving compartment (5) a cylindrical extension (55) is arranged which comprises an inner passage recess (56) which is in flow connection with the receiving compartment (5) in the open position of the cap part (3).

11. The improvement according to claim 10, characterized in that the extension (55) comprises an annular sealing surface (62) which cooperates with a complementarily formed annular sealing surface (63) of the second cap part (3) in the closure position thereof.

12. The improvement according to claim 8 characterized in that the second cap part (3) comprises four vanes (64 to 67) which are arranged at an angle of 90°

and disposed circumferentially on an outer wall (30) of the cap part (3).

13. The improvement according to claim 12, characterized in that the vanes (64 to 67) are provided with projections (68, 69) which project radially outwardly from outer edges of the vanes (64 to 67).

14. The improvement according to claim 8, characterized in that the closure cap (1) usable on a blood side of a dialyzer and is provided with an outer thread (50) arranged in a receiving compartment (52) for cooperating with an inner thread (51) of the dialyzer flange (4).

15. The improvement according to any one of claims 8 to 14, characterized in that the closure cap (1) is usable on a dialyzate side of a dialyzer and provided with an inner thread (74) for cooperating with an outer thread on the dialyzer flange.

16. The improvement according to claim 1, characterized in that the connection portion (16) is connected to the first portion (6) following an end region (11) thereof and its outer diameter is greater than the outer diameter of the first portion (6).

17. The improvement according to claim 16, characterized in that the connection portion (16) has an opened end side (17) adjoined inwardly by first, second and third subspaces (18, 19, 20).

18. The improvement according to claim 17, characterized in that the first subspace (18) immediately adjoins the end side (17) and has a greater inner diameter than the second subspace (19) and is connected to the latter via a step (21) arranged substantially perpendicularly to a longitudinal axis of the first cap part (2).

19. The improvement according to claim 17, characterized in that an inner surface (22) of the second subspace (19) forms a guide surface and the sealing means for the dialyzer flange (4).

20. The improvement according to claim 17, characterized in that the third subspace (20) comprises a frustoconical inner surface (23) which provides a gradual transition between the second subspace (19) and the third subchamber (9).

21. The improvement according to claim 17, characterized in that within the subspaces (18 to 20) concentrically to the connection portion (16) a pot-shaped insert member (24) is fixed having an outer surface (25) which defines with the inner surfaces of the subspaces a free flow passage which creates a flow connection between the open end side (17) of the connection portion (16) and the third subchamber (9) of the first portion (6).

22. The improvement according to claim 21, characterized in that the insert member (24) has an open end side (26) which lies preferably in a plane with the open end side (17).

23. The improvement according to claim 22, characterized in that the insert member (24) comprises a cylindrical boundary wall (27) which is connected at a side opposite the open end side (26) to a closure wall (28).

24. The improvement according to claim 23, characterized in that the closure wall (28) comprises an outer surface (29) directed towards the third subchamber (9).

25. The improvement according to claim 17, characterized in that the third subspace (20) forms a transition between the second subspace (19) and a fourth subspace (41) which is connected via a central connection recess (42) to the third subchamber (9).

26. The improvement according to claim 25, characterized in that the connection recess (42) is defined by an encircling stop wall (43) projecting inwardly to the longitudinal axis.

27. The improvement according to claim 26, characterized in that the stop wall (43) comprises a sealing surface (44) directed towards the third subchamber (9).

28. The improvement according to claim 1, characterized in that the second cap part (3) is pot-shaped and comprises a wall (30) which extends around a longitudinal axis and defines an inner space (31).

29. The improvement according to claim 28, characterized in that the inner space (31) is open at an end side (32) and at an opposite end side is closed by a closure wall (33) arranged substantially perpendicularly to the longitudinal axis.

30. The improvement according to claim 28, characterized in that the wall (30) comprises at least one connection opening (34 or 35) which connects the inner space (31) to an outer wall surface (36).

31. The improvement according to claim 30, characterized in that on the outer wall surface (36) an outwardly directing guide and retaining means (37) is arranged.

32. The improvement according to claim 31, characterized in that the guide and retaining means (37) comprises a resiliently yielding guide ring (38) arranged spaced from the outer wall surface (36) and a stop ring (39) directed outwardly from said guide ring (38).

33. The improvement according to claim 32, characterized in that the guide ring (38) is connected via a collar (40) to the wall (30).

34. The improvement according to claim 1, characterized in that the first cap part (2) is provided with an arresting means (45) which cooperates with a complementary arresting means (46) on the dialyzer flange (4) in the mounted state of the second cap part (2).

35. The improvement according to claim 34, characterized in that the cooperating arresting means and complementary arresting means (45, 46) comprise one of a snap-action, detent, screw and bayonet fastener.

36. The improvement according to claim 34, characterized in that the cooperating arresting means and complementary arresting means (45, 46) are formed as an intactness closure.

37. The improvement according to claim 36, characterized in that the complementary arresting means (46) on the dialyzer flange (4) is formed as nose projection which is provided with a defined intended breakage point.