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Molecular diagnosis of Alzheimer Disease

  • US 5,015,570 A
  • Filed: 05/13/1988
  • Issued: 05/14/1991
  • Est. Priority Date: 05/13/1988
  • Status: Expired due to Fees
First Claim
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1. A method for diagnosing Alzheimer Disease or a predisposition to develop Alzheimer Disease in an individual, comprising the step of determining the presence of an alteration in the normal DNA base sequence


  • space="preserve" listing-type="equation">'"'"' CAC TGT CGC TAT GAC AAC ACC GCC 3'"'"',
or its normal complementary DNA or RNA sequences, in a sample of the DNA or RNA of such individual by hybridization with an aligonucleotide probe.

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