Artificial retina device

• US 5,016,633 A
• Filed: 08/08/1989
• Issued: 05/21/1991
• Est. Priority Date: 08/08/1989
• Status: Expired due to Term

• Current Assignee: IMI Intelligent Medical Implants AG (Pixium Vision SA)
• Original Assignee: Alan Y. Chow
• Inventors: Chow, Alan Y.
• Primary Examiner(s): Frinks, Ronald
• Application Number:
  US07/390,562
• Time in Patent Office: 651 Days
• Field of Search: 623/4, 128/419 R, 128/783-785
• US Class Current: 607/53
• CPC Class Codes: A61F 2/14 Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/08 Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

A silicon chip device composed of a large array of densely packed microphotodiodes is implanted between the inner and outer retina layers, in patients with vision-deficient eyes suffering from retinal dysfunction, to allow for useful formed vision. The photoactive surface of each photodiode, with its silicon deposited or etched electrode, point towards the incident light. The device produces an amplitude-modulated current to stimulate the inner retinal layer. The device is intrinsically inert due to its doped silicon substrate nature.

Claims

1. An artificial retina device, comprising:

a plurality of discrete photodiodes disposed on one surface of a substrate, said photodiodes each including an active electrode layer overlaying a photosensitive layer, each photodiode being connected to an electrical ground, said photodiodes having electrical outputs that correspond to the amplitude of the light incident on said device, whereby said device can be implanted in the eye intermediate the inner retinal layer and the retinal pigment epithelium of outer layer of the retina, so that each of said photodiodes will stimulate directly individual or small groups of cells in the inner retinal layer corresponding to the light incident on said device.

2. The artificial retina device of claim 1, wherein said device is from 3 mm to 20 mm in its maximum width, and from 0.005 mm to 2 mm between said two surfaces.

3. The artificial retina device of claim 1 that further includes a grasping member.

4. The artificial retina device of claim 1 further including a plurality of openings between said two surfaces.

5. The artificial retina device of claim 1 wherein one or both surfaces are curved.

6. The retinal implant device of claim 1, wherein said first surface includes a plurality of protuberances that extend therefrom.

7. The retinal implant device of claim 1, wherein said first surface is flat.

8. The retinal implant device of claim 1 wherein said photosensitive layer comprises a P-doped layer, and said device further includes an intrinsic layer and a N-doped layer, said intrinsic layer being disposed between said P-doped layer and said N-doped layer.

9. The retinal implant device of claim 1 wherein said photosensitive layer comprises a N-doped layer and said device further includes an intrinsic layer and a P-doped layer, said intrinsic layer being disposed between said N-doped layer and said P-doped layer.

10. The retinal implant device of claim 8 wherein said active electrode is formed from polysilicon.

11. The retinal implant device of claim 9 wherein said active electrode is formed from polysilicon.

12. A surgical procedure for implanting a device of claim 1, comprising

making a horizontal incision temporal to the macula, parallel to and through the nerve fiber layer;

opening the potential space within the retina by irrigating with balanced salt solution;

inserting said device into said space intermediate the inner retinal layer and the retinal pigment epithelium of outer layer of the retina with said photodiodes facing light incident into said eye;

and closing said incision and space.

13. The surgical procedure of claim 12 wherein a plurality of burns are made around the periphery of said device to secure the device in position.

14. A method for producing artificial vision, comprising:

making an incision through the sclera posterior to the ora serata, through the choroidal vasculature, the outer retinal layer and into the potential space between the inner and outer retinal layer; and

inserting a device of claim 1 into said space whereby it is positioned in the macula area of the posterior pole of the eye.

15. A method for producing artificial vision, comprising:

implanting a device of claim 1 into the potential space of the retina between the retinal pigment epithelium and the inner retinal layer with the active electrode facing light incident the eye, whereby said device intercepts light after its passage through the nerve fiber layer and inner retinal layers of the eye, and produces discrete stimulation from inside the retina of bipolar cells, horizontal cells, amacrine cells and ganglion cells.