Device for immunoassay determinations
First Claim
1. An assay support, generally planar and elongated in shape, and comprising a gripping section, a sample receiving well section, and a connecting section therebetween, each of said sections being aligned along a longitudinal axis;
- said sample receiving well section comprising at least two spaced-apart receiving wells;
each of said wells having an open end on a first face of said support, a concave inner surface extending concavely into said support, and a convex outer surface which projects convexly from an opposed face of said support;
said convex outer surface of at least one of said wells provided with at least one stabilizing leg constructed and arranged to preclude rotation of said wells when resting on a flat surface;
said assay support provided with a leveling projection extending from said opposed face so as to cooperate with said at least one stabilizing leg to maintain said support level when resting on a flat surface;
said sample receiving section in the space between said wells comprises a dam means projecting from the first face of said support so as to preclude the flow of a liquid sample from one of said wells to another of said wells.
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Accused Products
Abstract
An assay device is provided which includes a support, generally planar and elongated in shape, upon which a biological binding reaction may take place. This assay support includes in its broadest aspect, three sections, a sample receiving well section at one end and a gripping section at the opposite end, with a connecting section therebetween. The sample receiving well section includes at least two spaced-apart receiving wells, generally at the end of the assay support, for the addition of binding reactants. Each of the wells has an open end on a first face of the support, a concave inner surface extending concavely into the support, and a convex outer surface which projects convexly from an opposed face of the support. These wells may serve as a depository to contain aliquots of binding reagents, as well as a sample under analysis, the sample under analysis possibly containing a substance that will bind to the binding reagents.
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Citations
18 Claims
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1. An assay support, generally planar and elongated in shape, and comprising a gripping section, a sample receiving well section, and a connecting section therebetween, each of said sections being aligned along a longitudinal axis;
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said sample receiving well section comprising at least two spaced-apart receiving wells;
each of said wells having an open end on a first face of said support, a concave inner surface extending concavely into said support, and a convex outer surface which projects convexly from an opposed face of said support;said convex outer surface of at least one of said wells provided with at least one stabilizing leg constructed and arranged to preclude rotation of said wells when resting on a flat surface; said assay support provided with a leveling projection extending from said opposed face so as to cooperate with said at least one stabilizing leg to maintain said support level when resting on a flat surface; said sample receiving section in the space between said wells comprises a dam means projecting from the first face of said support so as to preclude the flow of a liquid sample from one of said wells to another of said wells. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A plurality of detachably connected assay supports wherein each of said assay supports is generally planar and elongated in shape and comprises a gripping section, a sample receiving well section and a connecting section therebetween, each of said sections being aligned along a longitudinal axis;
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said sample receiving well section comprising at least two spaced-apart receiving wells;
each of said wells having an open end on a first face of said support, a concave inner surface extending concavely into said support, and a convex outer surface which projects convexly from an opposed face of said support;said convex surface of at least one of said wells provided with at least one stabilizing leg constructed and arranged so as to preclude rotation of said wells when resting on a flat surface; said assay support provided with a leveling projection extending from said opposed face so as to cooperate with said at least one stabilizing leg to maintain said support level when resting on a flat surface; said sample receiving well section in the space between said wells comprises dam means projecting from the first face of said planar support, so as to preclude the flow of a liquid sample from one of said wells to another of said wells. - View Dependent Claims (14, 15, 16)
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17. An assay support, useful in conducting immunoassay determinations of the ratio of IgG to IgM antibodies in biological samples, said support generally planar and elongated in shape, and comprising a gripping section, a sample receiving well section, and a connecting section therebetween, each of said sections being aligned along a longitudinal axis;
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said sample receiving well section comprising two spaced-apart receiving wells;
each of said wells having an open end on a first face of said support, a concave inner surface extending concavely into said support, said inner surface comprising concentric circles; and
a convex outer surface which projects convexly from an opposed face of said support;said convex outer surface of at least one of said wells includes at least one stabilizing leg adapted to preclude rotation of said wells when resting on a flat surface; said assay support comprises a leveling projection extending from said opposed face so as to cooperate with said at least one stabilizing leg to maintain said support level when resting on a flat surface;
said sample receiving well section also comprising in the space between said wells dam means projecting from the first face of said support so as to preclude the flow of a liquid sample from one of said wells to another of said wells.said dam means further comprising a labeling portion contiguous therewith and projecting from said first face of said support to a height equal to that of the dam means;
said labeling portion being generally triangular in shape with an apex extending toward one of said receiving wells. - View Dependent Claims (18)
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Specification