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3,4-diaminoquinoline and 3,4-diamino-5,6,7,8-tetrahydroquinoline compounds useful for improving psychoneural function

  • US 5,019,574 A
  • Filed: 09/28/1989
  • Issued: 05/28/1991
  • Est. Priority Date: 09/30/1988
  • Status: Expired due to Fees
First Claim
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1. A 4-aminoquinoline or 4-amino-5,6,7,8-tetrahydroquinoline compound represented by the formula:

  • ##STR155## wherein R1 is a hydrogen atom, a hydroxyl group, a linear or branched chain lower alkyl group or a cycloalkyl group which may be substituted by a hydroxyl group, a lower alkoxy group, a lower alkyl group or a cycloalkyl group which contains a carbonyl group, or a group --NH--B where B is a lower alkyl group, a cycloalkyl group, or a phenyl group;

    R2 and R3, which may be the same or different, each represents a hydrogen atom, a lower alkyl group, a lower alkyl carbonyl group, or when taken together, form a pyrrolidino group, a piperidino group, a morpholino group, or an N-methylpiperazinyl group, together with the nitrogen atom;

    or an acid addition salt of said quinoline or 5,6,7,8-tetrahydroquinoline compound; and

    when R1 is a hydrogen atom, R2 and R3 are neither a hydrogen atom nor an ethyl group at the same time.

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