Apparatus and method for detecting and processing impedance rheogram

• US 5,025,784 A
• Filed: 09/06/1988
• Issued: 06/25/1991
• Est. Priority Date: 09/05/1987
• Status: Expired due to Fees

• Current Assignee: Harbin Polytechnical University
• Original Assignee: Harbin Polytechnical University
• Inventors: Feng, Jianhua, Shao, Shuyong, Zhang, Xinchao
• Primary Examiner(s): Joworski, Francis
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/240,620
• Time in Patent Office: 1,022 Days
• Field of Search: 128/419 D, 128/419 PG, 128/734, 128/696, 128/700, 128/702, 128/716
• US Class Current: 607/5
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295
• CPC Class Codes: A61B 5/0809 by impedance pneumography

Abstract

An apparatus and method for detecting and processing an impedance rheogram includes a constant current source with output electrodes, an impedance signal detecting circuit having detecting electrodes, an ECG signal detecting circuit having detecting electrodes, a signal processing circuit and an output device. The impedance signal detecting circuit and ECG signal detecting circuit respectively, defect the impedance signal and ECG signal, the signal whereby processing circuit divides the impedance signal into cycles according to an R wave sequence, then performs linear interpolating for each cycle and in-phase superposing-averaging for a certain number of cycles, and restores the impedance waveform according to a predetermined number of interpolating points used for each cycle, so as to automatically trace arrhythmia and eliminate respiration interference to the impedance rheogram.

Claims

1. An apparatus for detecting and processing an impedance rheogram, comprising:

a constant current source for generating a constant current having a frequency range of 20-100 KHz and an amplitude of less than 2 mA;

a pair of output electrodes connected to said constant current source for applying the constant current to a subject'"'"'s body part;

a pair of voltage detecting electrodes for detecting from said body part of voltage signal which represents a change of impedance in response to the constant current applied to the said body part;

means for detecting an impedance signal from said voltage detecting electrodes and for further amplifying and filtering the impedance signal detected thereby;

ECG signal detecting electrodes adapted to be connected to the said body part for detecting an ECG signal generated by the said body part;

means for detecting the ECG signal generated by said ECG signal detecting electrodes, for amplifying and filtering the ECG signal detected, and for generating an R wave sequence from the ECG signal;

digital signal processing means connected to an output of each said means for detecting said impedance signal and said means for detecting said ECG signal wherein said impedance signal, ECG signal and R wave sequence are connected in parallel to said digital signal processing means; and

an output device connected to said digital signal processing means for displaying and recording the impedance signal and ECG signal;

wherein said digital signal processing means performs A/D converting and sampling of said impedance and ECG signals, divides said impedance signal into cycles according to said R wave sequence and performs linear interpolating processing within each cycle, said linear interpolation processing including selection of a predetermined number of interpolating points for each cycle, subsequently performs in-phase superposing-averaging processing of the impedance signal for a predetermined number of cycles and restores the impedance signal according to the interpolating points, and synchronously outputs the impedance and ECG signals to said output device.

2. The apparatus as claimed by claim 1, wherein said impedance signal detecting means includes a high frequency amplifier connected to said voltage detecting electrodes, an envelope detector connected to an output of said high frequency amplifier, a low-pass filter connected to an output of said envelope detector, and a low frequency amplifier connected to an output of said low-pass filter for providing an adequate level impedance signal, wherein the cut-off frequency of said low-pass filter is about 30 Hz to filter the high frequency interference in said impedance signal.

3. The apparatus as claimed in claim 1, wherein said ECG signal detecting means includes a high frequency amplifier connected to said ECG detecting electrodes, a band elimination filter connected to an output of said high frequency amplifier for filtering an operating frequency interference, a low-pass filter having a cut-off frequency of 100 Hz connected to an output of said band elimination filter, a low frequency amplifier connected to an output of said low-pass filter for providing an ECG signal of adequate level, and an R wave detector connected to an output of said band elimination filter for generating an R wave sequence.

4. The apparatus as claimed by claim 1, wherein said digital signal processing means includes and A/D converter connected to outputs of said impedance signal detecting means and ECG signal detecting means for synchronously converting said impedance signal and ECG signal into respective digital signal, interpolation processing means which samples said digital impedance and ECG signals at constant time intervals and divides said impedance signal into cycles according to said R wave sequence input from said ECG signal detecting means, then performs linear interpolation processing within each cycle for a predetermined number of points, a memory unit connected to an output of said interpolation processing means for storing interpolation results, superposing-averaging processing means which fetches a predetermined number of continuous cycles of interpolating results from said memory unit and conducts in-phase superposing-averaging processing thereon and restores the impedance waveform according to the predetermined number of interpolating points, and a D/A converter connected to an output of said superposing-averaging processing means for converting an output impedance waveform and synchronized ECG waveform into respective analog signals for parallel output.

5. The apparatus as claimed in claim 4, wherein said interpolation processing means performs 64 or 128 points of interpolation processing in each cycle and said superposing-averaging processing means performs superposing on 8 or 16 cycles.

6. The apparatus as claimed in claim 1, further comprising:

a smoothing filter connected to analog outputs of said digital signal processing means for smoothly filtering the impedance and ECG signals;

a calibrating circuit connected to an impedance output of said smoothing filter for calibrating its output signal; and

a differential circuit connected to the impedance output of said smoothing filter for generating the differential signal of said impedance signal;

wherein said smoothing filter, calibrating circuit and differential circuit are connected in parallel to said output device for displaying and recording the impedance and ECG signals.

7. The apparatus as claimed in claim 1, wherein each of said cycles may be of a different length according to said R wave sequence and sampling at said constant time interval will cause an actual number of samplings per cycle to vary according to the length of the cycle.

8. A method for detecting and processing impedance rheogram comprising the steps of:

1) applying a constant current having a frequency in the range of 20-100 KHz and an amplitude of less than 2mA to a part of a subject'"'"'s body;

2) detecting a voltage variation caused by a change of impedance of said body part under the effect of said constant current and using said voltage variation as an impedance signal;

3) simultaneously detecting the subject'"'"'s ECG signal and generating a R waveform sequence therefrom;

4) synchronously converting said impedance signal and ECG signal into respective digital signals and sampling the same at constant time intervals;

5) dividing said sampled impedance signal into cycles according to rising edges of said R wave sequence and conducting in each cycle a linear interpolation for a predetermined number of interpolation points;

6) performing in-phase superposing-averaging for a predetermined number of cycles of an interpolated impedance signal and restoring an impedance waveform according to said interpolating points; and

7) displaying and recording said impedance waveform and synchronized ECG waveform via an output device.

9. The method as claimed in claim 8, wherein said predetermined number of points in step 5) is 64 or 128 and said predetermined number of cycles in step 6) is 8 or 16.