Hypertension analyzer apparatus

• US 5,031,629 A
• Filed: 06/02/1989
• Issued: 07/16/1991
• Est. Priority Date: 06/02/1989
• Status: Expired due to Fees

• Current Assignee: Arthur P. Demarzo
• Original Assignee: Arthur P. Demarzo
• Inventors: DeMarzo, Arthur P.
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): Manuel, George
• Application Number:
  US07/360,992
• Time in Patent Office: 774 Days
• Field of Search: 128/670, 128/734, 128/682, 128/683, 128/680, 128/695, 128/696, 128/706, 128/707, 128/709, 128/710, 128/713, 128/715, 128/720
• US Class Current: 600/483
• CPC Class Codes: A61B 2560/0431 Portable apparatus, e.g. comprising a handle or case
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/303 Patient cord assembly, e.g. cable harness
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

The present invention is directed to an apparatus that is compact, portable and highly effective in performing a hemodynamic profile of a patient, and is particularly useful in generating such profiles for the purpose of diagnosing and treating hypertension. The apparatus includes noninvasive blood pressure and cardiac output monitors, computing means and the apparatus calculates a patient'"'"'s cardiac index and systemic vascular resistance index for use in diagnosing hypertension.

Claims

1. A self-contained compact, portable apparatus for noninvasively performing a hemodynamic profile of a patient, and particularly adapted for use in diagnosing hypertension, the apparatus comprising, in combination:

means for noninvasively monitoring and measuring thoracic impedance of the patient, and for generating electrical signals that are indicative of the measured thoracic impedance of the patient;

means for noninvasively monitoring and measuring the blood pressure of the patient, and for generating electrical signals that are indicative of the measured blood pressure levels of the patient;

detachable cuff means for application to the patient, said cuff means being adapted to be connected to said blood pressure monitoring and measuring means for providing blood pressure measurements of the patient thereto;

means for noninvasively monitoring and measuring the electrocardiological profile of the patient and for generating electrical signals that are indicative of the measured electro-cardiological profile of the patient;

detachable electrode means adapted to be connected to the patient and to the electrocardiological profile monitoring and measuring means for providing input signals thereof;

computing means operatively connected to each of said monitoring and measuring means and adapted to receive and process the electrical signals generated by each of said monitoring and measuring means, said computing means including printing means the printing reports of hemodynamic data, display means for displaying information relating to operation of the apparatus, and keyboard means for entering data concerning a patient and for controlling the operation of the apparatus; and

compact portable container means including mounting means located within the container means for housing each of said monitoring and measuring means and said computing means;

said computing means receiving said electrical signals from each of said monitoring and measuring means and generating a visual display on said display means that includes a plurality of hemodynamic indices and measurements including value for blood pressure, chart rate, cardiac index and systemic vascular resistance index of the patient being monitored, and also generating a written report of said values.

2. Apparatus as defined in claim 1 wherein the height and weight of the patient is entered on the keyboard means, said computing means being adapted to process the electrical signals generated from each of said monitoring and measuring means and produce said visual display and written report in relation to the height and weight of the patient being monitored.

3. Apparatus as defined in claim 2 wherein said computing means generates said values based upon an average of a predetermined number of measurement taken over a short period of time.

4. Apparatus as defined in claim 1 wherein said container means comprises a generally rectangular cross-sectional base portion having a cooperatively fitting cover portion that is adapted to open relative to the base portion, said base portion having sufficient depth to receive said computing means, and each of said monitoring and measuring means, said container means having a carrying handle and locking means for releasably locking said cover portion to said base portion.

5. APparatus as defined in claim 4 wherein the outside walls of said base portion and cover portion are fabricated of a substantially rigid material.

6. Apparatus as defined in claim 1 wherein said computing means includes a data base for correlating height and weight values of a patient to a value of L indicating the distance on a patient between properly placed electrodes of a cardiac monitoring means, for use in calculating the stroke volume in the equation:

space="preserve" listing-type="equation">SV=r×

(L/Z.sub.0).sup.2 ×

T×

dZ/dt

where

r is the resistivity of blood in ohm-cm

L is the distance between the sensing electrodes in cm

Z₀ is the basal impedance of the thorax in ohms

T is the ejection time in seconds, and

dZ/dt is the first derivative of the impedance change (Δ

Z) in the thorax during Δ

ejection time T.

7. Apparatus as defined in claim 1 wherein said thoracic impedance monitoring and measuring means is of the type which measures diathoracic impedance for a predetermined number of heart beats and generates an electric signal indicating the average value of said thoracic impedance for said predetermined number of heart beats, said computing means being adapted to select and receive a predetermined number of said electric signals and generate an average value of the same.

8. Apparatus as defined in claim 7 wherein said predetermined number of heart beats is 9 and said predetermined number of said electric signals is within the range of 1 to 10.

9. A self-contained compact, portable apparatus for noninvasively performing a hemodynamic profile of a patient, and particularly adapted for use in diagnosing hypertension, the apparatus comprising:

means for noninvasively monitoring and measuring thoracic impedance of the patient, and for generating electrical signals that are indicative of the measured thoracic impedance of the patient;

means for noninvasively monitoring and measuring the blood pressure of the patient, and for generating electrical signals that are indicative of the measured blood pressure levels of the patient;

detachable cuff means for application to the patient, said cuff means being adapted to be connected to said blood pressure monitoring and measuring means for providing blood pressure measurements of the patient thereto;

means for noninvasively monitoring and measuring the electrocardiological profile of the patient and for generating electrical signals that are indicative of the measured electrocardiological profile of the patient;

detachable electrode means adapted to be connected to the patient and to the electrocardiological profile monitoring and measuring means for providing input signals thereto;

computing means operatively connected to each of said monitoring and measuring means and adapted to receive and process the electrical signals generated by each of said monitoring and measuring means, said computing means including printing means for printing reports of hemodynamic data, display means for displaying information relating to the operation of the apparatus, and keyboard means for entering data concerning a patient, including the height and weight of the patient, said keyboard also being adapted to control the operation of the apparatus; and

compact portable container means having a rectangular base portion and a cover portion operable between an open position exposing the interior of said base portion and a closed position covering said base portion, said base portion including mounting means located therein for housing each of said monitoring and measuring means and said computing means;

said computing means receiving said electrical signals from each of said monitoring and measuring means and generating a plurality of hemodynamic indices and measurements including blood pressure, heart rate, cardiac index and systemic vascular resistance index of the patient being monitored.

10. Apparatus as defined in claim 9 wherein said computing means includes a data base for correlating height and weight values of a patient to a value of L indicating the distance on a patient between properly placed electrodes of a cardiac monitoring means, for use in calculating the stroke volume in the equation:

space="preserve" listing-type="equation">SV=r×

(L/Z.sub.0).sup.2 ×

T×

dZ/dt

where

r is the resistivity of blood in ohm-cm

L is the distance between the sensing electrodes in cm

Z₀ is the basal impedance of the thorax in ohms

T is the ejection time in seconds, and

dZ/dt is the first derivative of the impedance

change (Δ

Z) in the thorax during ejection time T.

11. Apparatus as defined in claim 9 said computing means in operative to generate a printed report that includes values for blood pressure, heart rate, cardiac index and systemic vascular resistance index of the patient being monitored.

12. Apparatus as defined in claim 11 wherein said printed report provided by said apparatus is sufficient to enable a medical practitioner to effectively prescribe the most appropriate combination of hypertension medication, a value of cardiac index above a predetermined value indicating that a negative inotrope type of medication should be most eficacious, a value of systemic vascular resistance index above a predetermined value indicating that a vasodilator type of medication should be most efficacious.

13. Apparatus as defined in claim 9 wherein said computing means generates a visual display on said display means that includes values for blood pressure, heart rate, cardiac index and systemic vascular resistance index of the patient being monitored.

14. Apparatus as defined in claim 9 wherein said blood pressure monitoring and measuring means is of the auscultatory type which requires an ECG input signal for its operation, said blood pressure monitoring and measuring means having a microphone adapted to be applied to the brachial artery of the patient, said microphone being connected thereto for providing said ECG input signals, the apparatus having leads interconnecting said blood pressure monitoring and measuring means to said thoracic impedance monitoring and measuring means for providing said ECG input signals thereto.

15. Apparatus as defined in claim 9 wherein manipulation of said keyboard means of said computing means is effective to initiate operation of each of said monitoring and measuring means during operation of said apparatus.