Analytical system for the determination of a component of a fluid

• US 5,035,862 A
• Filed: 12/09/1988
• Issued: 07/30/1991
• Est. Priority Date: 12/17/1987
• Status: Expired due to Fees

• Current Assignee: Boehringer Mannheim GmbH (Roche Holding AG)
• Original Assignee: Boehringer Mannheim GmbH (Roche Holding AG)
• Inventors: Lutz, Thomas, Fullemann, Rainer, Dietze, Werner
• Primary Examiner(s): Warden, Robert J.
• Assistant Examiner(s): Collins, Laura E.
• Application Number:
  US07/282,107
• Time in Patent Office: 963 Days
• Field of Search: 422/68.1, 422/66, 422/104, 436/155, 436/157, 436/169, 435/805, 219/10.57, 219/10.75
• US Class Current: 422/68.1
• CPC Class Codes: G01N 2035/00039 Transport arrangements specific to flat sample substrates, e.g. pusher blade
• CPC Class Codes: G01N 2035/00118 for multiple tests
• CPC Class Codes: G01N 2035/00356 Holding samples at elevated temperature (incubation)
• CPC Class Codes: G01N 35/00029 provided with flat sample substrates, e.g. slides G01N35/028 takes precedence

Abstract

An analytical system for the determination of a component of a fluid, especially blood or urine, is disclosed. It comprises test carriers, which have at least one test field, and an evaluating instrument for the measurement of a characteristic change in the test field.

In order to achieve rapid and selective heating of individual test fields, especially in test carriers that are multiple-test strips, the corresponding test field has a metallic conducting layer, which runs parallel to the test field and is in thermal contact with it. The evaluating instrument has an induction heater. The guiding mechanism of the test carrier in the evaluating instrument is designed so that the metallic conducting layer, at least before the measurement, is in the working area of the alternating magnetic field emanating from the induction heater.

Claims

1. An analytical system for measuring the concentration of a component, said system comprising:

a test carrier having a test field and a metallic conducting layer associated with said test field, said metallic conducting layer lying parallel to the test field and being in thermal contact with the test field, the test field containing a reagent which reacts with said component to produce a measurable change in said test field, said change being accelerated by heat;

an induction heater having means for producing an alternating magnetic field, said magnetic field having a working area in which a said metallic conducting layer is inductively heated when located therein;

means for guiding the test carrier so that the metallic conducting layer is in the working area of the alternating magnetic field; and

an evaluating instrument for measuring a change in the test field after the test field is heated, said change being characteristic of the concentration of the component.

2. The system of claim 1 wherein the metallic conducting layer is ferromagnetic.

3. The system of claim 1 wherein the metallic conducting layer is a metal foil.

4. The system of claim 1 wherein the test carrier is a test strip having a plurality of test fields adjacently disposed thereon, some of said test fields being in thermal contact with a metallic conducting layer.

5. The system of claim 1 wherein the test carrier is a test strip having a plurality of test fields adjacently disposed thereon, two test fields being in contact with respective metallic conducting layers having different thickness.

6. The system of claim 1 wherein the test carrier is a test strip having a plurality of test fields adjacently disposed thereon, two test fields being in contact with respective metallic conducting layers made from different materials.

7. The system of claim 1 further comprising a net, said net securing a test field layer to a base layer with a metallic conducting layer between said layers.

8. The system of claim 1 wherein said guiding means is adapted to cause the test carrier to pause at a plurality of stop points where a test field is in the working area of an alternating magnetic field.