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Method for predicting steady-state conditions

  • US 5,040,126 A
  • Filed: 10/15/1985
  • Issued: 08/13/1991
  • Est. Priority Date: 09/09/1981
  • Status: Expired due to Term
First Claim
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1. A method of predicting the equilibrium pressure of fluid in a chromatographic system during a chromatographic run comprising the steps of:

  • pumping fluid under pressure from a low start pressure, trough a transitory time to a stable equilibrium pressure;

    measuring the pressure of the fluid;

    taking the time derivative of said measured pressure;

    finding the maximum time derivative;

    multiplying the measured pressure at a point in time by a factor which is a ratio having as its numerator the value of the time derivative of said measured pressure at said point in time subtracted from the maximum time derivative and as its denominator the maximum time derivative.

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