Pulsed light blood oxygen content sensor system and method of using same

• US 5,040,538 A
• Filed: 09/05/1989
• Issued: 08/20/1991
• Est. Priority Date: 09/05/1989
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Siemens Pacesetter, Inc. (Abbott Laboratories Incorporated)
• Inventors: Mortazavi, Said
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/403,208
• Time in Patent Office: 714 Days
• Field of Search: 128/633, 128/634, 128/664, 128/665, 128/666
• US Class Current: 600/333
• CPC Class Codes: A61N 1/36557 controlled by chemical substances in blood

Abstract

A sensor for use with a rate-responsive pacemaker is disclosed which is responsive to blood oxygen content, thereby allowing the cardiac rate of the pacemaker to closely mimic the natural response pattern of the heart to changing physiological need. The sensor integrates the output from a photosensor driven by blood-reflected light from an LED, and when the integrated output reached a predetermined threshold latches the circuit, enabling the use of time to indicate the level of blood oxygen content. The sensor thus advantageously requires neither a voltage doubler in the driving circuitry, or an analog-to-digital converter in the output circuitry, reducing both complexity and power consumption of the blood oxygen sensor.

Claims

1. A blood oxygen sensor for use with a pacemaker to sense the level of oxygen in blood, said blood oxygen sensor comprising:

an LED for emitting light;

means for driving said LED to emit light beginning at a first time;

means for directing the light emitted by said LED onto blood and for allowing light reflected by blood to return to the sensor;

a photodetector for detecting the portion of light from said LED which is reflected by blood and returned to the sensor, said photodetector providing an output proportional to the portion of light from said LED which is reflected by blood;

an integrator for integrating said output from said photodetector and providing as an output an integrated voltage output;

means for determining a predetermined threshold value;

means for comparing said integrated voltage output with said predetermined threshold value and providing an output signal at a second time when said integrated voltage output reaches said predetermined threshold value; and

a

means for monitoring the interval between said fist time and said second time and providing an output signal indicative of the interval between said first time and aid second time, the interval between said first time and said second time being inversely related to the level of oxygen in blood.

2. A blood oxygen sensor as defined in claim 1, wherein said LED comprises:

an LED which emits light at a wavelength of approximately 660 nM.

3. A blood oxygen sensor as defined in claim 1, additionally comprising:

a first conductor for connection to a pacemaker at one end thereof;

a second conductor for connection to a pacemaker at one end thereof, said LED being connected across said first and second conductors and said means for driving being electrically connected across said first and second conductors.

4. A blood oxygen sensor as defined in claim 3, wherein said means for driving comprises:

means for supplying a current pulse, said first and second conductors having a first voltage therebetween when said LED is driven by said current pulse, said output signal provided by said comparing means being characterized by a second voltage between said first and second conductors.

5. A blood oxygen sensor as defined in claim 4, wherein said second voltage is less than said first voltage.

6. A blood oxygen sensor as defined in claim 4, wherein said comparing mean comprises:

means for latching connected between said first and second conductors, said output signal being provided by said latching means latching between said first and second conductors to cause the voltage therebetween to change from said first voltage to said second voltage.

7. A blood oxygen sensor as defined in claim 1, wherein said photodetector comprises:

a phototransistor.

8. A blood oxygen sensor as defined in claim 7, wherein said integrator and comparing means comprise:

a transistor, the collector of said transistor being connected to the base of said phototransistor, the base of said transistor being connected to the collector of said phototransistor, the emitter of said transistor being connected to said second conductor, the emitter of said phototransistor being connected to said first conductor;

a first transistor connected across the base emitter junction of said transistor; and

a second resistor connected across the base emitter junction of said phototransistor.

9. A blood oxygen sensor as defined in claim 8, wherein said transistor is a PNP transistor, and said phototransistor is an NPN phototransitor.

10. A blood oxygen sensor as defined in claim 8, wherein said first resistor has a substantially larger resistance than said secondresitor.

11. A blood oxygen sensor as defined in claim 8, wherein the cathode of said LED is connected to said first conductor, and the anode of said LED is connected to said second conductor.

12. A blood oxygen sensor as defined in claim 8, wherein said means for driving supplies an initialization current to said LED prior to said first time.

13. A blood oxygen sensor as defined in claim 12, wherein said initialization current is sufficiently small to limit the voltage across said first resistor to a value not sufficient to cause latching.

14. A blood oxygen sensor as defined in claim 12, wherein said means for driving supplies a current pulse to said LED beginning at said first time.

15. A blood oxygen sensor for use with a pacemaker to sense the level of oxygen in blood, said blood oxygen sensor comprising:

a first conductor for connection to a pacemaker at one end thereof;

a second conductor for connection o a pacemaker at one end thereof;

an LED connected between said first and second conductors, said LED for emitting light;

means for driving said LED to emit light beginning at a first time, said means for driving being electrically connected between said first and second conductors;

means for directing the light emitted by said LED onto blood and for allowing light reflected by blood to return to the sensor;

a phototransmistor for detecting the portion of light from said LED which is reflected by flood and returned to the sensor, the emitter of said phototransistor being connected to said first conductor;

a transistor, the collector of said transistor being connected to the base of said phototransistor, the base of said transistor being connected to the collector of said phototransistor, the emitter of said transistor being connected to said second conductor;

a first resistor connected across the base-emitter junction of said transistor;

a second resistor connected across the base-emitter junction of said phototransistor, said transistor and said phototransistor conducting at a second time dependant on the amount of light reflected by blood to said phototransistor; and

means for monitoring the interval between said first time and aid second time and providing an output signal indicative of the interval between said first time and said second time, the interval between said first time and said second time being inversely related to the level of oxygen in blood.

16. A blood oxygen sensor as defined in claim 15, wherein said means for driving comprises:

means for supplying a current pulse, said first and second conductors having a first voltage therebetween when said LED is driven by said current pulse, said output signal provided by said comparing means being characterized by a second voltage between said first and second conductors.

17. A blood oxygen sensor as defined in claim 15, wherein said comparing means comprises:

means for latching connected between said first and second conductors, said output signal being provided by said latching means latching between said first and second conductors to cause the voltage therebetween to drop from said first voltage to said second voltage.

18. A blood oxygen sensor as defined in claim 15, wherein said transistor is a PNP transistor, and said phototransistor is an NPN phototransitor.

19. A blood oxygen sensor as defined in claim 15, wherein said first resistor has a substantially larger resistance than said second resistor.

20. A blood oxygen sensor as defined in claim 15, wherein the cathode of said LED is connected to said first conductor, and the anode of said LED is connected to said second conductor.

21. A blood oxygen sensor as defined in claim 15, wherein said means for driving supplies an initialization current to said LED prior to said first time.

22. A blood oxygen sensor as defined in claim 21, wherein said initialization current is sufficiently small to limit the voltage across said first resistor to a value not sufficient to cause lacking.

23. A blood oxygen sensor as defined in claim 21, wherein said means for driving supplies a current pulse to said LED beginning at said first time.

24. A blood oxygen sensor for use with a pacemaker, said blood oxygen sensor comprising:

means for emitting light beginning at a first time;

means for directing the light emitted by said emitting means onto blood and for flowing light reflected by blood to return to the sensor;

means for detecting the portion of light from said emitting means which is reflected by blood and returned to the sensor, said detecting means providing an output proportional to the portion of light from said emitting means which is reflected by blood;

means for integrating said output from said detecting means and providing as an output an integrated voltage output;

means for determining a predetermined threshold value;

means for comparing said integrated voltage output with said predetermined threshold value and providing an output signal at a second time when said integrated voltage output reaches said predetermined threshold value; and

means for monitoring the interval between said first time and said second time and providing an output signal indicative of the interval between said first time and said second time, the interval between said first time and said second time being inversely related to the level of oxygen in said blood.

25. A method of determining the level of blood oxygen suing a sensor, said method comprising:

driving an LED to emit light beginning at a first time;

directing the light emitted by said LED onto blood and allowing light reflected by blood to return to the sensor;

;

detecting the portion of light from said LED which is reflected by said blood and returned to the sensor with a photodetector, said photodetector providing an output proportional to the portion of light from said LED which is reflected by said blood;

integrating said output from said photodetector with an integrator and providing as an output of said integrator an integrated voltage output;

comparing said integrated voltage output with a predetermined threshold value and providing an output signal at a second time when said integrated voltage output reaches said predetermined threshold value; and

monitoring the interval between said first time and said second time and providing an output signal indicative of the interval between said first time and said second time, the interval between said first time and said second time being inversely related to the level of oxygen in said blood.