Electrically controllable, non-occluding, body implantable drug delivery system
First Claim
1. An implantable drug delivery apparatus for long-term implantation within the body of an animal comprising:
- p1 (a) an implantable source of direct current potential;
(b) an elongated, flexible plastic tubular catheter body having a proximal end, a distal end and at least one lumen extending from said proximal end to said distal end, and lumens at said distal end being closed, except for a port extending through said catheter body near said distal end;
(c) first and second electrode means adapted to be connected to said source of direct current potential, said first electrode being contained within said lumen and said second electrode being a ring disposed on the exterior surface of said catheter body; and
(d) A liquid solution containing a drug in solution substantially filling said sumen and engulfing said first electrode, the connection of said first and second electrodes to said source driving said drug through said port.
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Accused Products
Abstract
An implantable apparatus for continuous or periodic introduction of a drug to a desired release point in the body comprises an implantable power source and an elongated flexible plastic tubular catheter having a lumen filled with the drug to be delivered and containing therein a first device electrode. The distal end of the catheter is closed and located near the distal end is a port which extends through the wall of the catheter to communicate with the lumen. Just proximal of the port is a surface electrode mounted on the exterior wall of the catheter body. Extending through the catheter and joined to the drive electrode and the surface electrode are conductors which couple those electrodes to the implanted power source. Energization of the electrodes with a predetermined direct current potential causes a flow of the ionized drug molecules out through the port and into the area surrounding the surface electrode.
301 Citations
11 Claims
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1. An implantable drug delivery apparatus for long-term implantation within the body of an animal comprising:
- p1 (a) an implantable source of direct current potential;
(b) an elongated, flexible plastic tubular catheter body having a proximal end, a distal end and at least one lumen extending from said proximal end to said distal end, and lumens at said distal end being closed, except for a port extending through said catheter body near said distal end; (c) first and second electrode means adapted to be connected to said source of direct current potential, said first electrode being contained within said lumen and said second electrode being a ring disposed on the exterior surface of said catheter body; and (d) A liquid solution containing a drug in solution substantially filling said sumen and engulfing said first electrode, the connection of said first and second electrodes to said source driving said drug through said port. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- p1 (a) an implantable source of direct current potential;
Specification