Pressure-sensitive adhesive compositions suitable for medical uses
First Claim
1. An adhesive composition comprising a polymer adhesive that is soluble or dispersible in water and is low-temperature curable to form a solid which is single-phase at ambient temperature, pressure-sensitive, dermatologically acceptable, moisture vapor-permeable, and resistant to dissolution when exposed to water.
4 Assignments
0 Petitions
Accused Products
Abstract
A dermatologically-acceptable, moisture vapor-permeable, pressure-sensitive adhesive composition that is a single-phase solid at ambient temperature and resists dissolution when exposed to water, comprises a polymer adhesive which is the product of a process comprising the steps of chain extending a water-soluble derivatized capped prepolymer which comprises a first terminal group and a low-temperature curable group, until the resultant polymer attains a determined level of tackiness, and then subjecting the polymer to low-temperature curing. The adhesive is used to advantage in medical products like adhesive bandages, plasters, dressings and surgical drapes, and can dissolve water-soluble bio-active additives.
160 Citations
53 Claims
- 1. An adhesive composition comprising a polymer adhesive that is soluble or dispersible in water and is low-temperature curable to form a solid which is single-phase at ambient temperature, pressure-sensitive, dermatologically acceptable, moisture vapor-permeable, and resistant to dissolution when exposed to water.
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40. A dermatologically-acceptable, moisture vapor-permeable, pressure-sensitive adhesive composition that is a single-phase solid at ambient temperature and resists dissolution when exposed to water, comprising a polymer adhesive which is the product of a process comprising the steps of
i) providing a water-soluble derivatized capped prepolymer which comprises a first terminal group and a low-temperature curable group, ii) subjecting said water-soluble derivatized capped prepolymer to chain extension in the presence of a chain extension agent reactive with said first terminal group, whereby a polymer is formed, until said polymer attains a determined level of tackiness, when said chain extension is halted by addition of a chain termination agent reactive with said first terminal groups, and iii) subjecting said polymer to low-temperature curing.
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43. An adhesive composition as claimed in soluble.
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50. A process for producing a polymer adhesive that is soluble or dispersible in water and is low-temperature curable to form a solid which is single-phase at ambient temperature, pressure-sensitive, dermatologically acceptable, moisture vapor-permeable, and resistant to dissolution when exposed to water, which comprises the steps of
i) providing a derivatized capped prepolymer comprising a plurality of first terminal groups, and ii) reacting said derivatized capped prepolymer with a chain extension agent reactive with said first terminal groups to effect chain extension of said derivatized capped prepolymer, whereby a polymer is formed, until said polymer attains a determined level of tackiness, when said chain extension is halted by addition of a chain termination agent reactive with said first terminal groups.
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51. A process for producing a polymer adhesive that is soluble or dispersible in water and is low-temperature curable to form a solid which is single-phase at ambient temperature, pressure-sensitive, dermatologically acceptable, moisture vapor-permeable, and resistant to dissolution when exposed to water, which comprises the steps of
i) reacting a compound comprising a plurality of hydroxyl groups and a polyisocyanate compound to form an isocyanate-terminated polyurethane capped prepolymer, ii) reacting a portion of the terminal isocyanate groups of said polyurethane capped prepolymer with a derivatizing agent comprising a group reactive with isocyanate and a low-temperature curable group to form a derivatized capped prepolymer, and iii) reacting said derivatized capped prepolymer with a chain extension agent reactive with isocyanate to effect chain extension of said derivatized capped prepolymer, whereby a polymer is formed, until said polymer attains a determined level of tackiness, when said chain extension is halted by addition of a chain termination agent reactive with isocyanate.
Specification