Ophthalmic solution for intraocular pressure adjustment
First Claim
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1. A method for lowering intraocular pressure which comprises instilling into the eye an opthalmic solution comprising an intraocular pressuring lowering amount of a compound of the formula II ##STR4## wherein R1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano;
- R2 is fluorine, trifluoromethyl, nitro or cyano; and
R3 is alkyl of 3 to 5 carbon atoms, hydroxyalkyl of 3 to 5 carbon atoms, cycloalkyl of 3 to 5 carbon atoms, 1-(3,4-methylenedioxy-phenyl)-2-propyl or 1-(p-hydroxy-phenyl)-2-propyl;
or a pharmaceutically acceptable salt thereof.
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Abstract
Disclosed are novel opthalmic solutions useful for the treatment of ocular hypertension and glaucoma. These contain mabuterol as a preferred active ingredient.
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Citations
3 Claims
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1. A method for lowering intraocular pressure which comprises instilling into the eye an opthalmic solution comprising an intraocular pressuring lowering amount of a compound of the formula II ##STR4## wherein R1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano;
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R2 is fluorine, trifluoromethyl, nitro or cyano; and R3 is alkyl of 3 to 5 carbon atoms, hydroxyalkyl of 3 to 5 carbon atoms, cycloalkyl of 3 to 5 carbon atoms, 1-(3,4-methylenedioxy-phenyl)-2-propyl or 1-(p-hydroxy-phenyl)-2-propyl; or a pharmaceutically acceptable salt thereof. - View Dependent Claims (2, 3)
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Specification