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Ophthalmic solution for intraocular pressure adjustment

  • US 5,049,587 A
  • Filed: 04/21/1989
  • Issued: 09/17/1991
  • Est. Priority Date: 04/21/1988
  • Status: Expired due to Fees
First Claim
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1. A method for lowering intraocular pressure which comprises instilling into the eye an opthalmic solution comprising an intraocular pressuring lowering amount of a compound of the formula II ##STR4## wherein R1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano;

  • R2 is fluorine, trifluoromethyl, nitro or cyano; and

    R3 is alkyl of 3 to 5 carbon atoms, hydroxyalkyl of 3 to 5 carbon atoms, cycloalkyl of 3 to 5 carbon atoms, 1-(3,4-methylenedioxy-phenyl)-2-propyl or 1-(p-hydroxy-phenyl)-2-propyl;

    or a pharmaceutically acceptable salt thereof.

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