QRS filter for real time heart imaging with ECG monitoring in the magnetic field of an NMR imaging system and NMR imaging apparatus employing such filter

• US 5,052,398 A
• Filed: 06/29/1990
• Issued: 10/01/1991
• Est. Priority Date: 06/29/1990
• Status: Expired due to Fees

• Current Assignee: North American Philips Corp. (Koninklijke Philips N.V.)
• Original Assignee: North American Philips Corp. (Koninklijke Philips N.V.)
• Inventors: Gober, Joel R.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/548,345
• Time in Patent Office: 459 Days
• Field of Search: 128/653 X, 128/696, 128/708
• US Class Current: 600/509
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening
• CPC Class Codes: G01R 33/28 Details of apparatus provided for in groups G01R33/44 - G01R33/64
• CPC Class Codes: G01R 33/5673 Gating or triggering based on a physiological signal other than an MR signal, e.g. ECG gating or motion monitoring using optical systems for monitoring the motion of a fiducial marker

Abstract

A pair of Butterworth 4th order filters are cascaded with an absolute value filter to filter the QRS wave of an ECG signal generated in a magnetic field of an NMR imaging system. The NMR system includes a magnet for producing a static B_O field and a set of coils for producing RF pulse induced fields in which an ECG monitoring system is located. The ECG monitoring system transmits the resultant QRS waves to a receiver which processes the received signals and applies the received signals to a display via the above filters. The -3 dB point of the high pass filter is at about 10 Hertz to filter the T-wave and Bo field induced breathing artifacts and the -3 dB point of the low pass filter is about 20 Hertz to filte the high frequency components of pulsed static field gradient noise created by the NMR system.

Claims

1. A QRS signal filter for use in real time with an NMR imaging system with negligible delay between the image and the filtered signal, said QRS signal having a given frequency range, said filter comprising:

a low pass filter for attenuating those portions of the QRS signal applied as an input and having a frequency above said given range to produce a first output signal, said low pass filter including means for imposing a first given phase shift on said output signal relative to said input signal; and

a high pass filter responsive to said output signal applied as an input thereto for attenuating those portions of an input signal applied thereto below said given range to produce a second output signal, said high pass filter including means for imposing a second given phase shift relative to the phase shift of the first output signal, said low and high pass filters being arranged so that said first and second phase shifts substantially cancel one another such that there is negligible time delay between said QRS signal applied to the low pass filter and said second output signal.

2. The filter of claim 1 further including absolute value filter means for processing said second output signal to correct for phase distortion in the second output signal.

3. The filter of claim 2 wherein the phase shift of the low pass filter is positive and the phase shift of the high pass filter is negative with the degree of said positive and negative shifts being about the same value.

4. The filter of claim 1 wherein said high and low pass filters are each fourth order Butterworth filters.

5. The filter of claim 1 including first and second operational amplifiers wherein the low pass filter comprises a pair of series connected input resistances connected to the input of the first operational amplifier and capacitive feedback means across said first operational amplifier and one of said input resistances and the high pass filter comprises a pair of series connected input capacitors connected to the input of the second operational amplifier and resistive feedback means across the latter amplifier and one of said input capacitors.

6. The filter of claim 1 wherein phase differences may be present between said high and low pass filters, said QRS signal filter further including full wave rectifier means for rectifying said second signal for correcting for said phase differences.

7. The filter of claim 1 wherein said low and high pass filters each include means for producing an output signal having a response of -24 dB per octave.

8. The filter of claim 1 wherein the attenuation response of the low pass filter is no less than about -3 dB at least about 20 Hertz and the attenuation response of the high pass filter is no less than about -3 dB at most about 10 Hertz.

9. The filter of claim 1 wherein the maximum combined time delay of the low and high pass filters is about 10 ms.

10. A QRS signal filter for use in real time with an NMR imaging system with negligible delay between the image and the filtered signal, said QRS signal being produced in the magnetic field of said system and having a given frequency range, said filter comprising:

a low pass filter responsive to said QRS signal applied as an input thereto and having about a -3 dB response at least about 20 Hertz and a response characteristic of about -24 dB per octave to produce a first output signal, said low pass filter including means for imposing a first given phase shift on said output signal relative to said input signal;

a high pass filter responsive to said output signal applied as an input thereto to produce a second output signal, said high pass filter having about a -3 dB response at most about 10 Hertz and a response characteristic of about -24 dB per octave, said high pass filter including means for imposing a second given phase shift relative to the phase shift of the first output signal, said low and high pass filters being arranged so that said first and second phase shifts substantially cancel one another at a given frequency such that there is negligible time delay between said QRS signal applied to the low pass filter and said second output signal; and

full wave rectifier means for rectifying said second output signal.

11. The filter of claim 10 wherein said high and low pass filters are each of the 4th order.

12. An NMR imaging system comprising:

magnet means for exposing a patient to a magnetic field, said patient creating signals in response to said magnetic field;

imaging means responsive to said patient signals for creating an image of a patient in said field; and

transmit and receive means for creating a patient QRS signal of a given frequency range in said magnetic field and for transmitting the QRS signal to said receive means;

said receive means including QRS signal filter means such that the image produced by said imaging means and said QRS signal are substantially in phase;

said filter means comprising;

a low pass filter for attenuating those portions of the QRS signal applied as an input and having a frequency above said given range to produce a first output signal, said low pass filter including means for imposing a first given phase shift on said output signal relative to said input signal; and

a high pass filter responsive to said output signal applied as an input thereto for attenuating those portions of an input signal applied thereto below said given range to produce a second output signal, said high pass filter including means for imposing a second given phase shift relative to the phase shift of the first output signal, said low and high pass filters being arranged so that said first and second phase shifts substantially cancel one another such that there is negligible time delay between said QRS signal applied to the low pass filter and said second output signal.

13. The filter of claim 12 wherein said low pass filter has about a -3 dB response at least about 20 Hertz and a response characteristic of about -24 dB per octave and the high pass filter has about a -3 dB response at most about 10 Hertz and a response characteristic of about -24 dB per octave.

14. An NMR imaging system comprising:

magnet means for exposing a patient to a magnetic field, said patient creating signals in response to said magnetic field;

imaging means responsive to said patient signals for creating an image of a patient in said field; and

transmit and receive means for creating a patient QRS signal of a given frequency range in said magnetic field and for transmitting the QRS signal to said receive means;

said receive means including QRS signal filter means for filtering the QRS signal such that the image produced by said imaging means and said QRS signal are substantially in phase wherein there is negligible time delay between said created image and said filtered QRS signal.

15. The system of claim 14 wherein said filter means comprises cascaded high and low pass filters arranged to provide respective phase shifts which substantially cancel one another to thereby provide said negligible time delay.