Diffusion and/or filtration apparatus

• US 5,053,130 A
• Filed: 08/26/1988
• Issued: 10/01/1991
• Est. Priority Date: 08/31/1987
• Status: Expired due to Term

• Current Assignee: Gambro Dialysatoren GmbH (Baxter International Inc.)
• Original Assignee: Gambro Dialysatoren GmbH & Company KG (Baxter International Inc.)
• Inventors: Raff, Manfred, Spranger, Kurt
• Primary Examiner(s): Dawson, Robert A.
• Assistant Examiner(s): WALKER, WANDA LYNNE
• Application Number:
  US07/237,504
• Time in Patent Office: 1,131 Days
• Field of Search: 210/321.65, 210/321.69, 210/321.71, 210/321.78, 210/321.79, 210/321.87, 210/321.88, 55/158
• US Class Current: 210/321.79
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: B01D 2313/205 characterised by the shape
• CPC Class Codes: B01D 2313/21 Specific headers, end caps
• CPC Class Codes: B01D 63/0231 using supporting structures, e.g. filaments for weaving mats
• CPC Class Codes: Y02A 20/131 Reverse-osmosis
• CPC Class Codes: Y10T 29/49604 Filter
• CPC Class Codes: Y10T 29/49801 Shaping fiber or fibered material
• CPC Class Codes: Y10T 29/49885 with coating before or during assembling
• CPC Class Codes: Y10T 29/49984 and casting

Abstract

The present invention relates to a diffusion and/or filtration apparatus, including a housing which consists of a cylindrical open-ended main part closed by two end caps and provided with an inlet and an outlet for a fluid. This fluid is adapted to flow through the fibers of a bundle of semipermeable hollow fibers which are arranged between two end walls within the housing. Additionally, the housing includes at least a second outlet for another fluid, with this fluid being adapted to be removed from the space outside the fibers through this second outlet, the ends of the hollow fibers being moulded into the end walls of the housing and opened by a cutting.

Claims

1. A diffusion/filtration apparatus comprising:

a) housing means, said housing means defining a longitudinally extending internal chamber including a first end and a second end;

b) a bundle of semi-permeable hollow fibers disposed within said internal chamber, said hollow fibers extending longitudinally from said first end of said housing to said second end of said housing, said hollow fibers having an outer surface, and a first end and a second end corresponding to said first end and said second end of said internal chamber;

c) end wall means supporting said first and second ends of said hollow fibers within said internal chamber so as to sealingly separate said first and second ends of said hollow fiber from said outer surface of said hollow fiber between said first and second ends thereof;

d) first inlet means for the introduction of a fluid into said first end of said housing means;

e) first outlet means for the evacuation of a fluid from said second end of said housing means;

f) second outlet means for the evacuation of a fluid from said internal chamber at a location between said first and second end of said housing means;

g) at least one ring member disposed between said end wall means and said housing means at one of said first and second ends of said internal chamber, said ring member being in direct contact with said housing and having a shape corresponding to said housing and defining a cavity between said ring member and said hollow fibers, the coefficient of adhesion between said end wall means and said ring member being lower than the coefficient of adhesion between said end wall means and said housing, whereby the structural integrity of said housing means and the seal between said ends of said hollow fibers and said outer surface of said hollow fibers is enhanced; and

h) at least one sealing ring interposed between said end wall and said first inlet means.

2. The apparatus according to claim 1 including support means within said cavity for longitudinally supporting said end wall means.

3. The apparatus according to claim 2 wherein said ring member includes an inner surface and an outer surface, and wherein said support means comprise a flange extending inwardly from said inner surface of said ring member.

4. The apparatus according to claim 3 wherein said flange extends inwardly as to said bundle of hollow fibers so as to provide support therefor.

5. The apparatus according to claim 2 wherein said support means are integral with said housing.

6. The apparatus according to claim 5 wherein said support means comprise longitudinally extending tongue means extending from a predetermined location on said housing means between said first and second ends thereof into said end wall means.

7. The apparatus according to claim 2 including ring support means for supporting said ring member from said housing.

8. The apparatus according to claim 7 wherein said ring support means comprises an annular groove in said housing, said ring member being longitudinally engaged in said annular groove.

9. The apparatus according to claim 7 wherein said ring member includes an inner surface and an outer surface, and wherein said support means comprises a flange extending inwardly from said inner surface of said ring member.

10. The apparatus according to claim 1 wherein said first inlet means is defined by a first end cap covering said first end of said housing and said first outlet means is defined by a second end cap covering said second end of said housing.

11. The apparatus according to claim 10 wherein said first and second end caps are applied to said first and second ends of said housing by a means selected from the group consisting of welding and gluing.

12. A diffusion/filtration apparatus comprising:

a) housing means, said housing means defining a longitudinally extending internal chamber including a first end and a second end;

b) a bundle of semi-permeable hollow fibers disposed within said internal chamber, said hollow fibers extending longitudinally from said first end of said housing to said second end of said housing, said hollow fibers having an outer surface, and a first end and a second end corresponding to said first end and said second end of said internal chamber;

c) end wall means supporting said first and second ends of said hollow fibers within said internal chamber so as to sealingly separate said first and second ends of said hollow fiber from said outer surface of said hollow fiber between said first and second ends thereof;

d) first inlet means for the introduction of a fluid into said first end of said housing means, said first inlet means being defined by a first end cap covering said first end of said housing;

e) first outlet means for the evacuation of a fluid from said second end of said housing means, said first outlet means being defined by a second end cap covering said second end of said housing, said first and second end caps being applied to said first and second ends of said housing in a fluid-tight manner;

f) second outlet means for the evacuation of a fluid from said internal chamber at a location between said first and second end of said housing means; and

g) at least one ring member disposed between said end wall means and said housing means at one of said first and second ends of said internal chamber, said ring member being in direct contact with said housing and having a shape corresponding to said housing and defining a cavity between said ring member and said hollow fibers, the coefficient of adhesion between said end wall means and said ring member being lower than the coefficient of adhesion between said end wall means and said housing, whereby the structural integrity of said housing means and the seal between said ends of said hollow fibers and said outer surface of said hollow fibers is enhanced.

13. The apparatus according to claim 12 including support means within said cavity for longitudinally supporting said end wall means.

14. The apparatus according to claim 13 wherein said ring member includes an inner surface and an outer surface, and wherein said support means comprise a flange extending inwardly from said inner surface of said ring member.

15. The apparatus according to claim 14 wherein said flange extends inwardly as to said bundle of hollow fibers so as to provide support therefor.

16. The apparatus according to claim 13 wherein said support means are integral with said housing.

17. The apparatus according to claim 16 wherein said support means comprise longitudinally extending tongue means extending from a predetermined location on said housing means between said first and second ends thereof into said end wall means.

18. The apparatus according to claim 13 including ring support means for supporting said ring member from said housing.

19. The apparatus according to claim 18 wherein said ring support means comprises an annular groove in said housing, said ring member being longitudinally engaged in said annular groove.

20. The apparatus according to claim 12 including at least one sealing ring interposed between said end wall and said first inlet means.

21. A diffusion/filtration apparatus comprising:

a) housing means, said housing means defining a longitudinally extending internal chamber including a first end and a second end;

b) a bundle of semi-permeable hollow fibers disposed within said internal chamber, said hollow fibers extending longitudinally from said first end of said housing to said second end of said housing, said hollow fibers having an outer surface, and a first end and a second end corresponding to said first end and said second end of said internal chamber;

c) end wall means supporting said first and second ends of said hollow fibers within said internal chamber so as to sealingly separate said first and second ends of said hollow fiber from said outer surface of said hollow fiber between said first and second ends thereof;

d) first inlet means for the introduction of a fluid into said first end of said housing means;

e) first outlet means for the evacuation of a fluid from said second end of said housing means;

f) second outlet means for the evacuation of a fluid from said internal chamber at a location between said first and second end of said housing means; and

g) at least one ring member disposed between said end wall means and said housing means at one of said first and second ends of said internal chamber, so as to prevent contact between said end wall means and said housing means, said ring member having a shape corresponding to said housing and defining a cavity between said ring member and said hollow fibers, the coefficient of adhesion between said end wall means and said ring member being lower than the coefficient of adhesion between said end wall means and said housing, whereby the structural integrity of said housing means and the seal between said ends of said hollow fibers and said outer surface of said hollow fibers is enhanced.

22. The apparatus according to claim 21, including support means within said cavity for longitudinally supporting said end wall means.

23. The apparatus according to claim 22 wherein said support means are integral with said housing.

24. The apparatus according to claim 23 wherein said support means comprise longitudinally extending tongue means extending from a predetermined location on said housing means between said first and second ends thereof into said end wall means.

25. The apparatus according to claim 22 including ring support means for supporting said ring member from said housing.

26. The apparatus according to claim 25 wherein said ring support means comprises an annular groove in said housing, said ring member being longitudinally engaged in said annular groove.

27. The apparatus according to claim 25 wherein said ring member includes an inner surface and an outer surface, and wherein said support means comprises a flange extending inwardly from said inner surface of said ring member.

28. The apparatus according to claim 27 including at least one sealing ring interposed between said end wall and said first inlet means.

29. The apparatus according to claim 21 wherein said ring member includes an inner surface and an outer surface, and wherein said support means comprise a flange extending inwardly from said inner surface of said ring member.

30. The apparatus according to claim 29 wherein said flange extends inwardly as to said bundle of hollow fibers so as to provide support therefor.

31. The apparatus according to claim 21 wherein said first inlet means is defined by a first end cap covering said first end of said housing and said first outlet means is defined by a second end cap covering said second end of said housing.

32. The apparatus according to claim 31 wherein said first and second end caps are applied to said first and second ends of said housing by a means selected from the group consisting of welding and gluing.

33. A diffusion/filtration apparatus comprising:

a) housing means, said housing means defining a longitudinally extending internal chamber including a first end and a second end;

b) a bundle of semi-permeable hollow fibers disposed within said internal chamber, said hollow fibers extending longitudinally from said first end of said housing to said second end of said housing, said hollow fibers having an outer surface, and a first end and a second end corresponding to said first end and said second end of said internal chamber;

c) end wall means supporting said first and second ends of said hollow fibers within said internal chamber so as to sealingly separate said first and second ends of said hollow fiber from said outer surface of said hollow fiber between said first and second ends thereof;

d) first inlet means for the introduction of a fluid into said first end of said housing means;

e) first outlet means for the evacuation of a fluid from said second end of said housing means;

f) second outlet means for the evacuation of a fluid from said internal chamber at a location between said first and second end of said housing means;

g) at least one ring member disposed between said end wall means and said housing means at one of said first and second ends of said internal chamber, said ring member having a shape corresponding to said housing and defining a cavity between said ring member and said hollow fibers, the coefficient of adhesion between said end wall means and said ring member being lower than the coefficient of adhesion between said end wall means and said housing, whereby the structural integrity of said housing means and the seal between said ends of said hollow fibers and said outer surface of said hollow fibers is enhanced; and

h) support means integral for said housing, said support means comprising longitudinally extending tongue means extending from a predetermined location on said housing means between said first and second ends thereof into said end wall means for longitudinally supporting said end wall means.

34. The apparatus according to claim 33 including ring support means for supporting said ring member from said housing.

35. The apparatus according to claim 34 wherein said ring support means comprises an annular groove in said housing, said ring member being longitudinally engaged in said annular groove.

36. The apparatus according to claim 33 wherein said first inlet means is defined by a first end cap covering said first end of said housing and said first outlet means is defined by a second end cap covering, said second end of said housing.

37. The apparatus according to claim 36 wherein said first and second end caps are applied to said first and second ends of said housing by a means selected from the group consisting of welding and gluing.

38. The apparatus according to claim 33 including at least one sealing ring interposed between said end wall and said first inlet means.

39. A diffusion/filtration apparatus comprising:

a) housing means, said housing means defining a longitudinally extending internal chamber including a first end and a second end;

b) a bundle of semi-permeable hollow fibers disposed within said internal chamber, said hollow fibers extending longitudinally from said first end of said housing to said second end of said housing, said hollow fibers having an outer surface, and a first end and a second end corresponding to said first end and said second end of said internal chamber;

c) end wall means supporting said first and second ends of said hollow fibers within said internal chamber so as to sealingly separate said first and second ends of said hollow fiber from said outer surface of said hollow fiber between said first and second ends thereof;

d) first inlet means for the introduction of a fluid into said first end of said housing means;

e) first outlet means for the evacuation of a fluid from said second end of said housing means;

f) second outlet means for the evacuation of a fluid from said internal chamber at a location between said first and second end of said housing means;

g) at least one ring member disposed between said end wall means and said housing means at one of said first and second ends of said internal chamber, said ring member having a shape corresponding to said housing and defining a cavity between said ring member and said hollow fibers, the coefficient of adhesion between said end wall means and said ring member being lower than the coefficient of adhesion between said end wall means and said housing, whereby the structural integrity of said housing means and the seal between said ends of said hollow fibers and said outer surface of said hollow fibers is enhanced; and

h) support means within said cavity for longitudinally supporting said end wall means.

40. The apparatus according to claim 39 wherein said ring member includes an inner surface and an outer surface, and wherein said support means comprise a flange extending inwardly from said inner surface of said ring member.

41. The apparatus according to claim 40 wherein said flange extends inwardly as to said bundle of hollow fibers so as to provide support therefor.

42. The apparatus according to claim 39 wherein said support means are integral with said housing.

43. The apparatus according to claim 42 wherein said support means comprise longitudinally extending tongue means extending from a predetermined location on said housing means between said first and second ends thereof into said end wall means.

44. The apparatus according to claim 39 wherein said first inlet means is defined by a first end cap covering said first end of said housing and said first outlet means is defined by a second end cap covering said second end of said housing.

45. The apparatus according to claim 44 wherein said first and second end caps are applied to said first and second ends of said housing by a means selected from the group consisting of welding and gluing.

46. The apparatus according to claim 39 including at least one sealing ring interposed between said end wall and said first inlet means.

47. A diffusion/filtration apparatus comprising:

a) housing means, said housing means defining a longitudinally extending internal chamber including a first end and a second end;

b) a bundle of semi-permeable hollow fibers disposed within said internal chamber, said hollow fibers extending longitudinally from said first end of said housing to said second end of said housing, said hollow fibers having an outer surface, and a first end and a second end corresponding to said first end and said second end of said internal chamber;

c) end wall means supporting said first and second ends of said hollow fibers within said internal chamber so as to sealingly separate said first and second ends of said hollow fiber from said outer surface of said hollow fiber between said first and second ends thereof;

d) first inlet means for the introduction of a fluid into said first end of said housing means;

e) first outlet means for the evacuation of a fluid from said second end of said housing means;

wherein said support means comprise a flange extending inwardly from said inner surface of said ring member;

f) second outlet means for the evacuation of a fluid from said internal chamber at a location between said first and second end of said housing means; and

g) at least one ring member disposed between said end wall means and said housing means at one of said first and second ends of said internal chamber, said ring member having a shape corresponding to said housing and defining a cavity between said ring member and said hollow fibers, said ring member being in direct contact with said housing means, and said end wall means at said one of said first and second ends of said internal chamber having a first portion in contact with said ring member comprising a substantial portion of said end wall means, and having a second portion comprising a minor portion of said end wall means engaging said housing means between said one of said first and second ends of said internal chamber and said at least one ring member, said end wall means including slot means therein at a location adjacent to said second portion of said end wall means, the coefficient of adhesion between said first portion of said end wall means and said ring member being lower than the coefficient of adhesion between said second portion of said end wall means and said housing, whereby the structural integrity of said housing means and the seal between said ends of said hollow fibers and said outer surface of said hollow fibers is enhanced, while at the same time a seal is provided between said at least one of said first and second ends of said internal chamber and said internal chamber.

48. The apparatus according to claim 47 including support means within said cavity for longitudinally supporting said end wall means.

49. The apparatus according to claim 48 wherein said ring member includes a inner surface and an outer surface, and

50. The apparatus according to claim 47 including at least one sealing ring interposed between said end wall and said first inlet means.