Spiroid braided suture

• US 5,059,213 A
• Filed: 03/26/1990
• Issued: 10/22/1991
• Est. Priority Date: 03/26/1990
• Status: Expired due to Term

• Current Assignee: United States Surgical Corporation (Medtronic Plc)
• Original Assignee: United States Surgical Corporation (Medtronic Plc)
• Inventors: Hain, Matthew R., Koyfman, Ilya, Chesterfield, Michael P.
• Primary Examiner(s): Pellegrino, Stephen C.
• Assistant Examiner(s): Jackson, Gary
• Application Number:
  US07/499,173
• Time in Patent Office: 575 Days
• Field of Search: 606/228-231, 87/7, 428/224, 138/123, 139/317
• US Class Current: 606/228
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61L 17/005 containing a biologically active substance, e.g. a medicament or a biocide
• CPC Class Codes: A61L 17/04 Non-resorbable materials
• CPC Class Codes: A61L 17/12 Homopolymers or copolymers of glycolic acid or lactic acid
• CPC Class Codes: A61L 2300/406 Antibiotics
• CPC Class Codes: A61L 2300/414 Growth factors
• CPC Class Codes: D04C 1/12 Cords, lines, or tows
• CPC Class Codes: D10B 2509/04 Sutures

Abstract

A suture is provided with a solid spiroid braid construction. The suture exhibits greater flexibility, better hand and less chatter and drag than tubular braided sutures of known construction.

Claims

1. A suture of solid spiroid braid construction wherein for a given overall suture denier, the number of yarns and denier of individual filaments comprising a yarn are related to each other as follows:

space="preserve" listing-type="tabular">______________________________________ Overall Denier of Suture Number of Individual Denier Yarns Filaments ______________________________________ from about 50 from about 6 from about 0.2 to about 125 to about 15 to about 1.8 greater than from about 6 from about 0.2 about 125 to to about 15 to about 1.8 about 200 greater than from about 6 from about 0.2 about 200 to to about 15 to about 1.8 about 300 greater than from about 6 from about 0.2 about 300 to to about 15 to about 1.8 about 500 greater than from about 9 from about 0.2 about 500 to to about 20 to about 1.8 about 800 greater than from about 12 from about 0.2 about 800 to to about 25 to about 1.8 about 1200 greater than from about 12 from about 0.2 about 1200 to to about 25 to about 1.8 about 2000 greater than from about 15 from about 0.2 about 2000 to to about 25 to about 1.8 about 4000. ______________________________________

2. The suture of claim 1 exhibiting reduced tissue chatter and/or drag relative to a tubular braided suture of equivalent size.

3. The suture of claim 1 exhibiting increased knot security relative to a tubular braided suture of equivalent size.

4. The braided suture of claim 1 wherein for a given overall suture denier, the number of yarns and denier of individual filaments comprising a yarn are related to each other as follows:

space="preserve" listing-type="tabular">______________________________________ Overall Denier of Suture Number of Individual Denier Yarns Filaments ______________________________________ from about 50 from about 6 from about 0.8 to about 125 to about 12 to about 1.4 greater than from about 6 from about 0.8 about 125 to to about 12 to about 1.4 about 200 greater than from about 6 from about 0.8 about 200 to to about 12 to about 1.4 about 300 greater than from about 9 from about 0.8 about 300 to to about 12 to about 1.4 about 500 greater than from about 12 from about 0.8 about 500 to to about 15 to about 1.4 about 800 greater than from about 15 from about 0.8 about 800 to to about 20 to about 1.4 about 1200 greater than from about 15 from about 0.8 about 1200 to to about 20 to about 1.4 about 2000 greater than from about 24 from about 0.8 about 2000 to to about 34 to about 1.4 about 4000. ______________________________________

5. The suture of claim 1 wherein the individual filaments are fabricated from a non-absorbable material.

6. The suture of claim 5 wherein the non-absorbable material is cotton, silk, polyamide or polyolefin.

7. The suture of claim 1 wherein the individual filaments are fabricated from a bio-absorbable polymer.

8. The suture of claim 7 wherein the individual filaments are fabricated from a polymer derived at least in part from one or more monomers selected from the group consisting of glycolic acid, glycolide, lactic acid and lactide.

9. The suture of claim 1 wherein the individual filaments are fabricated from a bio-absorbable polymer.

10. The suture of claim 9 wherein the individual filaments are fabricated from a polymer derived at least in part from one or more monomers selected form the group consisting of glycolic acid, glycolide, lactic acid and lactide.

11. The suture of claim 1 surface coated with a composition enhancing one or more functional properties of the suture.

12. The suture of claim 1 containing at least one medico-surgically useful substance.

13. The suture of claim 12 wherein the medico-surgically useful substance is a Human Growth Factor.

14. The suture of claim 1 filled with a filling composition comprising a surgical wound healing enhancing amount of at least one Human Growth Factor and as carrier therefor at least one water soluble, liquid polyhydroxy compound and/or ester thereof.

15. The implantable surgical device of claim 14 wherein the polyhydroxy compound is glycerol.

16. The suture of claim 14 wherein the filling composition includes a thickener.

17. The suture of claim 16 wherein the thickener is a saturated aliphatic hydroxycarboxylic acid of the general formula ##STR2## wherein R is a hydrogen or methyl and R'"'"' is a metal selected from the group consisting of alkali metal and alkaline earth metal and n is 0 or 1 and hydrates thereof.

18. The suture of claim 17 wherein the thickener is calcium lactate.

19. The suture of claim 14 wherein the carrier is glycerol and the thickener is calcium lactate.

20. The suture of claim 1 treated with a storage stabilizing agent.

21. The suture of claim 20 wherein the storage stabilizing agent is glycerol.