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Optical sensor for selective detection of substances and/or for the detection of refractive index changes in gaseous, liquid, solid and porous samples

  • US 5,071,248 A
  • Filed: 11/14/1988
  • Issued: 12/10/1991
  • Est. Priority Date: 05/29/1985
  • Status: Expired due to Term
First Claim
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1. An optical sensor for detecting chemical, biochemical or biological substance in a sample, comprising:

  • a waveguiding structure formed by a waveguiding film covering a substrate, wherein the waveguiding film has a refractive index at least 1% higher than the refractive index of the substrate;

    a diffraction grating contained in the waveguiding structure; and

    a chemoresponsive non-chromophore layer covering the waveguiding film in a region around the diffraction grating, wherein the chemoresponsive non-chromophore layer changes its real part of the complex refractive index in response to the binding of the substances to be assayed and has a thickness exact or more than one wavelength.

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