Cuvette handling

• US 5,071,625 A
• Filed: 01/20/1988
• Issued: 12/10/1991
• Est. Priority Date: 02/27/1985
• Status: Expired due to Fees

• Current Assignee: Il Holding SpA (Werfen SA)
• Original Assignee: Fisher Scientific Co. (Thermo Fisher Scientific Incorporated)
• Inventors: Nelson, Larry A., Tiffany, Thomas O., Kelln, Norman G.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Trautman, Kimberly A.
• Application Number:
  US07/145,976
• Time in Patent Office: 1,420 Days
• Field of Search: 422/64, 422/65, 422/66, 422/67, 422/72, 422/73, 422/102, 422/258, 356/36, 356/246
• US Class Current: 422/72
• CPC Class Codes: G01N 2035/00306 Housings, cabinets, control panels (details)
• CPC Class Codes: G01N 2035/00316 Detecting door closure
• CPC Class Codes: G01N 2035/00495 Centrifuges
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 2035/0448 composed of interchangeable ring elements
• CPC Class Codes: G01N 35/02 using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations G01N35/0098 and G01N35/0099 take precedence

Abstract

An analysis system of the concurrent type has a multicuvette unit supply station, a loading station, an analysis station, and transport mechanism for transporting cuvette units in correlated orientation between the several stations. Each cuvette unit includes mechanical interlock structure that cooperates with orientation structure at each of the several stations and with orientation structure carried by the transport mechanism so that continuity of cuvette orientation information is maintained throughout loading and concurrent analysis of the several samples in the cuvette unit.

Claims

1. A multicuvette rotor for use in a centrifugal analyzer, said rotor comprising a body portion that defines a circumferential array of elongated cuvettes disposed about a centrally located aperture, interlock structure at the periphery of said body portion for engaging alignment structure, and spacer structure carried by said body portion so that, when said rotors are in stacked relation with said interlock structure engaged with said alignment structure, the body portions of said rotors are spaced apart to allow circulation of air between said body portions and the cuvettes of said stacked rotors are in aligned orientation.

2. The rotor of claim 1 wherein said alignment structure is a key member and said interlock structure is a notch that receives said key member.

3. The rotor of claim 1 wherein said spacer structure comprises a plurality of projections that extend from one surface of said rotor body portion.

4. The rotor of claim 3 wherein said projections include spaced arcuate portions that extend upwardly from the upper surface of said rotor.

5. The rotor of claim 1 wherein each said elongated cuvette includes a radial outer wall portion, structure defining a first chamber for receiving a first constituent and a loading port through which said first constituent is introduced into said first chamber, structure defining a second chamber region for receiving a second constituent, a second loading port through which said second constituent is introduced into said second chamber region, divider structure between said first and said chamber regions that defines a transfer passage between said first and second chamber regions through which said first constituent may flow into said second chamber region for forming a reaction product with said second constituent, and structure defining an analysis region adjacent said radial outer wall portion of said cuvette where said reaction product is subjected to analysis.

6. A centrifugal analyzer system comprising a storage structure storing rotors, wherein each of said rotor includes a body portion that defines a circumferential array of elongated cuvettes disposed about a centrally located aperture, interlock structure at the periphery of said body portion for engaging orientation structure, and spacer structure carried by said body portion, said storage structure including tower means for supporting said rotors in stacked spaced relations, orientation structure extending along the length of said tower means for engaging said interlock structure at the periphery of said rotor body portions so that, when said rotors are in stacked relation with said interlock structure engaged with said orientation structure, the body portions of said rotors are spaced apart to allow circulation of air between said body portions and the cuvettes of said stacked rotors are in aligned orientation, and release means for releasing said rotors sequentially from said tower means.

7. The system of claim 6 wherein said orientation structure includes a vertically extending key member and said interlock structure includes a notch at the periphery of each of said rotor body portions that receives said key member.

8. The system of claim 6 wherein said orientation structure includes a plurality of vertically extending spaced key members and said interlock structure includes a plurality of notches at the periphery of each of said rotor body portions that are correspondingly spaced to receive said key members, and said tower includes a plurality of spaced ring members secured to said key members to form a cage assembly.

9. The system of claim 8 wherein said spacer structure comprises a plurality of projections that extend from one surface of each of said rotor body portions.

10. The system of claim 9 wherein each said elongated cuvette includes a radial outer wall portion, structure defining a first chamber for receiving a first constituent and a loading port through which said first constituent is introduced into said first chamber, structure defining a second chamber region for receiving a second constituent, a second loading port through which said second constituent is introduced into said second chamber region, divider structure between said first and second chamber regions that defines a transfer passage between said first and second chamber regions through which said first constituent may flow into said second chamber region for forming a reaction product with said second constituent, and structure defining an analysis region adjacent said radial outer wall portion of said cuvette where said reaction product is subjected to analysis.