Device for carrying out extemporaneous quantitative diagnostic tests on whole blood

• US 5,071,772 A
• Filed: 02/07/1989
• Issued: 12/10/1991
• Est. Priority Date: 02/08/1988
• Status: Expired due to Fees

• Current Assignee: Arturo Corchia, Raffaele Beli
• Original Assignee: Arturo Corchia, Raffaele Beli
• Inventors: Corchia, Arturo, Beli, Raffaele
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US07/307,253
• Time in Patent Office: 1,036 Days
• Field of Search: 436/169, 436/170, 435/805, 422/56, 422/57
• US Class Current: 422/424
• CPC Class Codes: G01N 33/523 the element being adapted for a specific analyte
• CPC Class Codes: G01N 33/70 involving creatine or creatinine
• CPC Class Codes: G01N 33/92 involving lipids, e.g. cholesterol , lipoproteins, or their receptors steroid hormones G01N33/743
• CPC Class Codes: Y10S 435/805 Test papers

Abstract

A device for carrying out extemporaneous quantitative diagnostic tests on the whole blood which comprises:

a) a rigid plastic strip, to the end of which there is cemented a substrate containing a reactive substance which undergoes a selective color reaction respectively with the substance to be determined in the blood, and

a visual colorimetric reference scale specific for each of the examined substances and possibly corrected so as to directly read the content of the examined substance in the plasma from the test carried out the whole blood.

Claims

1. A device for carrying out extemporaneous quantitative diagnostic tests on whole blood by means of colorimetric determination of uricemia, creatininemia, azotemia, and cholesterolemia as single tests, said device comprising:

(a) a rigid plastic strip, to the end of which there is cemented, by means of an inert glue, a substrate containing an inert substance, magnesium trisilicate as a stabilizing substance and a reactive substance which undergoes a selective color reaction, said reactive substance being selected from the group consisting of phosphotungstic acid, 1;

1 parts by weight picric acid and sodium bicarbonate, diacetyl monoxime and the Liebermann-Buchard reagent; and

(b) a visual colorimetric reference scale specific for each of the examined substances.

2. A device as claimed in claim 1, wherein said substrate is paper.

3. A device as claimed in claim 1, wherein said inert glue is silicone.

4. A device as claimed in claim 1, wherein said inert substance is selected from the group consisting of glycerol, PVC, gelatine and carboxymethylcellulose.

5. A device for carrying out extemporaneous quantitative diagnostic tests on whole blood by means of colorimetric determination of uricemia, creatininemia, azotemia, and cholesterolemia as single tests, said device comprising:

(a) a rigid plastic strip, to the end of which there is cemented, by means of a silicone glue, a paper substrate containing an inert substance selected from the group consisting of glycerol, PVC, gelatine and carboxymethylcellulose, magnesium trisilicate as stabilizing substance and a reactive substance which undergoes a selective color reaction, said reactive substance being selected from the group consisting of phosphotungstic acid, 1;

1 parts by weight picric acid and sodium bicarbonate, diacetyl monoxime and the Liebermann-Buchard reagent; and

(b) a visual colorimetric reference scale specific for each of the examined substances.