Device for measuring the modification time of the physical state of a fluid medium

• US 5,072,610 A
• Filed: 03/27/1991
• Issued: 12/17/1991
• Est. Priority Date: 12/30/1987
• Status: Expired due to Fees

• Current Assignee: Servio
• Original Assignee: Servio
• Inventors: Martinoli, Jean-Luc, Vilain, Pascal, Rousseau, Alain
• Primary Examiner(s): Lacey, David L.
• Assistant Examiner(s): REDDING, DAVID A
• Application Number:
  US07/679,124
• Time in Patent Office: 265 Days
• Field of Search: 435/13, 436/69, 422/72, 422/73, 73/64.1, 366/273, 366/274, 356/39
• US Class Current: 73/53.01
• CPC Class Codes: G01N 11/10 by moving a body within the material
• CPC Class Codes: G01N 33/4905 Determining clotting time of blood by chemical methods G01N33/86, C12Q1/54

Abstract

A device for the measurement of time at which the physical state of a fluid medium is modified, comprises a vertical cup which contains the fluid and the necessary reagents, and in which a ferromagnetic ball is placed and is driven in rotation by an external magnetic field. The cup has at its lower part an annular travel path for the ball and it comprises a detection device which delivers an electric signal whenever the ball passes in front of it which is associated with a measurement unit determining the variation of the time interval between two consecutive passages of the ball.

Claims

1. A device for measuring the time of change of the physical state of a fluid sample comprising:

a container for holding the fluid sample;

a ferromagnetic member positioned and arranged so as to be movable in the bottom of the container along a predetermined circular path;

a driving means for generating a periodic rotating magnetic field to said ferromagnetic member which imparts to said member a sustained circular motion along said path; and

a detecting means for detecting the variations of frequency of said circular motion of said ferromagnetic member during the time of change in the physical state of the fluid sample, said detecting means further comprising means for measuring the relative speed of said sustained circular motion of said ferromagnetic member and the relative speed of said periodic rotating magnetic field during the time of change of the physical state of the sample fluid,

and means for comparing said measured relative speeds to provide the time of change of physical state of the sample fluid.

2. A device as claimed in claim 1, wherein said container is a vertically arranged cylinder having an axis of symmetry and a bottom provided with said circular path centered on said axis of symmetry, said driving means comprise a generally cylindrical ferromagnetic core vertically arranged under said cylinder and coaxial therewith, said core having an upper projection having a surface portion facing said ferromagnetic member, said driving means further comprising motor means drivingly coupled to said core for rotating it about said axis and means for magnetizing said core, and said measuring means comprise means for detecting the respective passage of said ferromagnetic member and of said surface portion of said core in a predetermined angular position and means for measuring the time interval between the said respective passages.

3. The device as claimed in claim 1, wherein said driving means include means for imparting to said ferromagnetic member a rotational speed and a drive force which have variable values as a function of the test carried out and of the duration of the measurement.

4. The device as claimed in claim 3, wherein said means for imparting a variable speed of rotation and a variable drive force are such that said values have at the beginning and at the end of the measurement first and second respective level stretches, the values corresponding to the first stretch being higher than those corresponding to the second stretch and gradually decreasing from the first to the second stretch.

5. The device of claim 1 further comprising an optical densitomer which comprises:

an optical filter; and

a light source in the form of a LED fed from a microprocessor, said microprocessor electrically connected to said LED and a photodiode;

whereby a light beam produced by said LED is transmitted from said microprocessor, through said container and said optical filter to the photodiode.