Method and apparatus for detecting urinary constituents

• US 5,073,500 A
• Filed: 12/28/1988
• Issued: 12/17/1991
• Est. Priority Date: 01/08/1988
• Status: Expired due to Fees

• Current Assignee: INAX Corporation (LIXIL Group Corp.)
• Original Assignee: INAX Corporation (LIXIL Group Corp.)
• Inventors: Shirai, Kenji, Saito, Shiro, Kawamoto, Ryuichi, Sakakibara, Shigeru
• Primary Examiner(s): Chin, Peter
• Application Number:
  US07/291,168
• Time in Patent Office: 1,084 Days
• Field of Search: 422/82, 436/53, 436/174, 4/300, 4/340, 4/341, 128/760, 128/771
• US Class Current: 436/53
• CPC Class Codes: A61B 5/14507 specially adapted for measuring characteristics of body fluids other than blood devices for taking samples of body liquids A61B10/0045
• CPC Class Codes: A61B 5/20 for measuring urological functions restricted to the evaluation of the urinary system A61B5/4375 takes precedence
• CPC Class Codes: G01N 33/493 urine
• CPC Class Codes: Y10T 436/118339 with formation of a segmented stream
• CPC Class Codes: Y10T 436/25 including sample preparation

Abstract

A method and an apparatus for measuring the concentration values of constituents of urine collected in a toilet bowl. A conduit extends from the urine-collecting portion of the bowl to a concentration-measuring device. A gas injector is mounted beside the conduit to intermittently inject gas into the conduit, for dividing the urine contained in the conduit into aliquots. The concentration values of urinary constituents of each aliquot are measured.

Claims

1. A method of investigating urinary constituents with a measuring device, comprising the steps of:

collecting urine in a urine collection chamber of a toilet bowl defined by a housing having an open end for receiving the urine, a partition member positioned to divide the housing into said urine collection chamber and a water chamber, said partition member having an opening for receiving a piston, said piston being slidably and sealingly mounted in said opening, said piston having a cross section smaller than the cross section of the urine collection chamber, a lower end of said piston having water tight sealing means in engagement with said water chamber;

diluting the collected urine by moving said piston into the collection chamber to expel a portion of the collected urine, withdrawing the piston from the collection chamber, and adding diluting liquid from said water chamber to the remaining portion of the collected urine, said water chamber having inlet and outlet means for receiving and discharging water, conduit means for delivering and discharging water from said water chamber, means in said conduit means for controlling the flow of water to the inlet and outlet means of said water chamber, said conduit means being operatively connected to an inlet in said urine collection chamber, said urine collection chamber having an outlet means for delivering the urine sample;

forcing the diluted urine into a conduit to supply the urine to the measuring device;

injecting gas into the urine contained in the conduit to divide the urine into plural aliquots which are separated from each other by intervening gas; and

introducing the aliquots successively into the measuring device to investigate constituents of the aliquots.

2. A method of investigating urinary constituents as set forth in claim 1, wherein the step of injecting gas into the urine involves intermittently injecting the gas to divide the urine contained in the conduit into the aliquots.

3. A method of investigating urinary constituents as set forth in claim 1, further including the step of diluting each aliquot at a desired rate of dilution after the urine contained in the conduit is divided into the aliquots by intermittently injecting gas into the conduit.

4. A method of investigating urinary constituents as set forth in claim 1, wherein a different reagent is added to each different aliquot of the urine which is separated in the conduit.

5. A method of investigating urinary constituents as set forth in claim 1, wherein reagents of the same kind but having different values of concentration are added to the aliquots of the urine which are separated in the conduit.

6. A method of investigating urinary constituents as set forth in claim 1, further including the steps of mixing together the urine and the reagents to form homogeneous mixtures after the reagents are added to the aliquots of urine which are separated in the conduit.

15. An apparatus for investigating urinary constituents as set forth in claim 1, further including the step of intermittently injecting a reagent into each aliquot of urine with a reagent adder to measure the concentration of a constituent of each aliquot.

7. An apparatus for investigating urinary constituents, comprising:

a toilet bowl having a urine-collecting portion, said urine-collecting portion comprised of a water chamber having inlet and outlet means for receiving and discharging water and a urine collection and dilution chamber defined by a housing having an open end for receiving the urine, a partition member positioned to divide the housing into said urine collection and dilution chamber and said water chamber, said partition member having an opening for receiving a piston, said piston being slidably and sealingly mounted in said opening, said piston having a cross section smaller than the cross section of the urine collection and dilution chamber, a lower end of said piston having water tight sealing means in engagement with said water chamber, wherein said water chamber further comprises conduit means for delivering and discharging water from said water chamber, means in said conduit means for controlling the flow of water to the inlet and outlet means of said water chamber, said conduit means being operatively connected to an inlet in said urine collection and dilution chamber, said urine collection and dilution chamber having an outlet means for delivering the urine sample;

a measuring device for detecting constituents of urine;

a conduit for forcing urine from the urine-collecting portion into the measuring device; and

an injection means for injecting gas into the conduit such that the injected gas divides the urine contained in the conduit into aliquots.

8. An apparatus for investigating urinary constituents as set forth in claim 7, wherein a means for diluting urine is mounted either in the urine-collecting portion of the toilet bowl or beside the conduit.

9. An apparatus for investigating urinary constituents as set forth in claim 7, wherein a reagent adder is disposed beside the conduit and downstream of the injection means.

10. An apparatus for investigating urinary constituents as set forth in claim 8, wherein a reagent adder is mounted beside the conduit and downstream of both the injection means and the diluting means.

11. An apparatus for investigating urinary constituents as set forth in claim 9, wherein a means for mixing together urine and the reagent is mounted beside the conduit and between the reagent adder and the measuring device that measures concentration of a urinary constituent.

12. An apparatus for investigating urinary constituents as set forth in claim 11, wherein the mixing means consists of a spirally shaped tube.

13. An apparatus for investigating urinary constituents as set forth in claim 7, wherein the measuring device is a spectrophotometer which measures concentration.

14. An apparatus for investigating urinary constituents as set forth in claim 7, wherein a display device that displays the results of a measurement is connected with the measuring device for measuring concentration.

16. An apparatus for investigating urinary constituents as set forth in claim 7, further including a reagent adder disposed beside the conduit and downstream of the injection means, the reagent adder being capable of intermittently injecting a reagent into each aliquot of urine separated by the gas.

17. An apparatus for investigating urinary constituents as set forth in claim 7, wherein said measuring device includes a light-transmitting portion through which urine flows, a light source, a light-receiving device disposed on the opposite side of the light-transmitting portion from the light source, and a lens mounted between the light source and the light-transmitting portion for focusing light into the urine, the light-transmitting portion being made from a material that transmits light.

18. An apparatus for investigating urinary constituents as set forth in claim 7, further including

a reagent adder mounted beside the conduit and capable of injecting a reagent into the conduit.

19. An apparatus for investigating urinary constituents as set forth in claim 17, wherein said light source consists of two or more light-emitting means emitting different wavelengths of light.

20. An apparatus for investigating urinary constituents as set forth in claim 7, wherein a plurality of conduits are provided, and wherein each conduit is equipped with the injection means and the measuring device.

21. An apparatus for measuring urinary constituents, comprising:

a toilet bowl having a urine-collecting portion, said urine-collecting portion comprised of a water chamber having inlet and outlet means for receiving and discharging water and a urine collection and dilution chamber defined by a housing having an open end for receiving the urine, a partition member positioned to divide the housing into said urine collection and dilution chamber and said water chamber, said partition member having an opening for receiving a piston, said piston being slidably and sealingly mounted in said opening, said piston having a cross section smaller than the cross section of the urine collection and dilution chamber, a lower end of said piston having water tight sealing means in engagement with said water chamber, wherein said water chamber further comprises conduit means for delivering and discharging water from said water chamber, means in said conduit means for controlling the flow of water to the inlet and outlet means of said water chamber, said conduit means being operatively connected to an inlet in said urine collection and dilution chamber, said urine collection and dilution chamber having an outlet means for delivering the urine sample;

a constituent analyzer for analyzing the urinary constituents;

a conduit for forcing the urine collected in the urine-collecting portion into the constituent analyzer;

a processing unit for storing output data from the analyzer, reading stored data and processing data in a desired manner; and

a display means for displaying the results of data processing delivered from the processing unit.

22. An apparatus for measuring urinary constituents, comprising:

a toilet bowl having a lower portion in which a device for investigating urinary constituents is mounted, the device including a water chamber having inlet and outlet means for receiving and discharging water and a urine collection and dilution chamber defined by a housing having an open end for receiving the urine, a partition member positioned to divide the housing into said urine collection and dilution chamber and said water chamber, said partition member having an opening for receiving a piston, said piston being slidably and sealingly mounted in said opening, said piston having a cross section smaller than the cross section of the urine collection and dilution chamber, a lower end of said piston having water tight sealing means in engagement with said water chamber, wherein said water chamber further comprises conduit means for delivering and discharging water from said water chamber, means in said conduit means for controlling the flow of water to the inlet and outlet means of said water chamber, said conduit means being operatively connected to an inlet in said urine collection and dilution chamber, said urine collection and dilution chamber having an outlet means for delivering the urine sample;

a processing unit for storing output data from the device, reading stored data and processing data in a desired manner; and

a display means for displaying the results of data processing delivered from the processing unit.