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Apparatus for in vivo analysis of biological compounds in blood or tissue by microdialysis and mass spectrometry

  • US 5,078,135 A
  • Filed: 05/31/1989
  • Issued: 01/07/1992
  • Est. Priority Date: 05/31/1989
  • Status: Expired due to Fees
First Claim
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1. An apparatus for measuring specific biological compounds in a living animal, comprising:

  • an implantable microdialysis probe having a channel with a perfusate input and a dialysate output, said channel including a dialyzing membrane;

    a continuous source of perfusate connected to said perfusate input;

    mass spectrometer means for measuring an amount of specific biological compounds in said dialysate; and

    switch valve means, connected between said dialysate output and said mass spectrometer means, positionable in a first position to collect dialysate and positionable in a second position to transfer collected dialysate to said mass spectrometer means.

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