Compositions and in situ methods for forming films on body tissue
First Claim
Patent Images
1. A liquid composition for in situ formation of medicament films on body tissue, comprising:
- (a) 0.1 to 20 percent by weight of hydroxypropyl cellulose;
(b) an esterification agent which reacts with the hydroxypropyl cellulose to form a reaction product which is soluble in the solvent of paragraph (c), but insoluble in body fluids at body temperatures;
(c) a non-toxic volatile solvent for said hydroxypropyl cellulose and said reaction product; and
(d) a separate medicinal component carried by said liquid composition selected from the group consisting of hydrocortisone, hydrocortisone acetate, betamethasone dipropionate, triamainolone acetonide, lidocaine hydrochloride, dibucaine hydrochloride.
7 Assignments
0 Petitions
Accused Products
Abstract
A film-forming composition for topical application of medicaments to body tissues. The film-forming composition includes hydroxypropyl cellulose; a non-toxic volatile solvent for said hydroxypropyl cellulose and said reaction product, and an esterification agent which reacts with the hydroxypropyl cellulose to form a reaction product which is soluble in the solvent. The medicinal compound is selected from the group consisting of hydrocortisone, hydrocortisone acetate, betamethasone dipropionate, triamainolone acetonide, lidocaine hydrochloride, dibucaine hydrochloride.
67 Citations
7 Claims
-
1. A liquid composition for in situ formation of medicament films on body tissue, comprising:
-
(a) 0.1 to 20 percent by weight of hydroxypropyl cellulose; (b) an esterification agent which reacts with the hydroxypropyl cellulose to form a reaction product which is soluble in the solvent of paragraph (c), but insoluble in body fluids at body temperatures; (c) a non-toxic volatile solvent for said hydroxypropyl cellulose and said reaction product; and (d) a separate medicinal component carried by said liquid composition selected from the group consisting of hydrocortisone, hydrocortisone acetate, betamethasone dipropionate, triamainolone acetonide, lidocaine hydrochloride, dibucaine hydrochloride. - View Dependent Claims (2, 3, 4, 5, 6, 7)
-
Specification