Method for alleviating and diagnosing symptoms of heart block

• US 5,083,564 A
• Filed: 06/01/1990
• Issued: 01/28/1992
• Est. Priority Date: 06/01/1990
• Status: Expired due to Fees

• Current Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Original Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Inventors: Scherlag, Benjamin J.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/531,960
• Time in Patent Office: 606 Days
• Field of Search: 128/419 PG
• US Class Current: 607/9
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

A method for alleviating and diagnosing syndromes of heart block wherein a stimulus is continuously or intermittently delivered via a single electrode catheter at a site in a heart in close proximity to the A-V junction in the heart. The subthreshold stimuli were sufficient to cause impulses in the atrium to pass through the damaged His bundle to the ventricle and the stimuli were set at a level below a level required to excite the heart tissue. The delivery of the stimuli alleviates the symptoms of heart block. In one application, the delivery of the stimuli is used for diagnosing heart block when delivery of the stimuli induces the symptoms of heart block in the patient with partial or covert conduction disease.

Claims

1. A method for alleviating the symptoms of heart block comprising:

generating subthreshold stimuli; and

delivering the subthreshold stimuli at the A-V junction in close proximity to the His bundle, the stimuli being sufficient to cause impulses from the atrium of the heart to pass through the damaged His bundle to the ventricles of the heart and the stimuli being below a level required to excite the heart tissue.

2. The method of claim 1 wherein the subthreshold stimuli are delivered continuously or intermittently.

3. The method of claim 1 wherein the step of delivering the stimuli further comprises:

connecting one end of an electrode catheter at the A-V junction in close proximity to the His bundle and connecting the opposite end of the electrode catheter for receiving the subthreshold stimuli; and

conducting the stimuli through the electrode catheter and delivering the stimuli to the heart via the connection of the end of the electrode catheter to the heart.

4. The method of claim 1 wherein the stimulus is a DC current having an amplitude sufficient to cause impulses in the atrium to pass to ventricle via the His bundle and the amplitude being below a level required to excite the heart tissue.

5. The method of claim 1 wherein the stimulus is a train of pulses with each pulse having an amplitude sufficient to cause impulses in the atrium to pass to ventricle via the damaged His bundle and the amplitude being below a level required to excite the heart tissue.

6. The method of claim 5 wherein the step of delivering the stimuli to the heart further comprises:

sensing atrial impulses of the heart; and

delivering each pulse in the train of pulses to the heart at a time immediately following an atrial impulse (P wave).