Homogeneous mammalian hematopoietic stem cell composition
First Claim
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1. A cell composition consisting essentially of as the cellular population viable murine hematopoietic Sca-1+ stem cells from a genetically identical or congenic source.
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Abstract
Highly concentrated hematopoietic stem cell compositions are provided which are substantially free of differentiated or dedicated hematopoietic cells. The cells are obtained by subtraction of cells having particular markers and selection of cells having particular markers. The resulting composition may be used to provide for individual or groups of hematopoietic lineages, to reconstitute stem cells of the host, and to identify an assay for a wide variety of hematopoietic growth factors.
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7 Claims
- 1. A cell composition consisting essentially of as the cellular population viable murine hematopoietic Sca-1+ stem cells from a genetically identical or congenic source.
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