Organism signal measuring apparatus

• US 5,092,340 A
• Filed: 04/12/1989
• Issued: 03/03/1992
• Est. Priority Date: 10/17/1986
• Status: Expired due to Term

• Current Assignee: Terumo Kabushiki Kaisha
• Original Assignee: Terumo Kabushiki Kaisha
• Inventors: Hirano, Toshinori, Fujii, Tadashi, Yamaguchi, Keiji, Go, Takafumi
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US07/347,893
• Time in Patent Office: 1,056 Days
• Field of Search: 128/696, 128/702, 128/703, 128/704, 364/413.06
• US Class Current: 600/508
• CPC Class Codes: A61B 5/333 Recording apparatus specially adapted therefor
• CPC Class Codes: A61B 5/35 by template matching
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives

Abstract

An apparatus for achieving a long-term organism signal measurement, for example, an ECG waveform measurement includes measuring means (1) and input means (2) for setting and inputting organism signal analysis data in the measuring means (1). By supplying via the input means (2) organism signal analysis data unique to an organism to be measured into the measuring means (1), there is conducted a learning operation of the characteristics of the organism signals of the subject. Thereafter, the measurement and analysis of the organism signals are achieved for a long period of time by use of the measuring means (1). The measurement is accomplished after the characteristics of the organism signals of the subject are learned, and hence the reliability is increased. In addition, the realtime measurement and analysis are conducted by the measuring means (1) so as to store only abnormal waveforms, which facilitates the judgement thereof to be conducted by a doctor.

Claims

1. An organism signal measuring apparatus for measuring organism signals of a subject for a predetermined period of time, comprising:

measuring means for measuring the organism signals of the subject for the predetermined period of time, including means for performing realtime analysis on the organism signals to produced results of the analysis according to feature values determining normality and abnormality of the organism signals, and means for storing the results of the analysis and for subsequently outputting the results of the analysis;

measurement control means for receiving the results of the analysis performed by said measuring means during a preliminary period of time, including means for determining feature values of normal and abnormal organism signals measured by said measuring means during the preliminary period of time with evaluation of what is normal and abnormal judged by an inspector, and means for generating a normal histogram and an abnormal histogram for each of the feature values using the organism signals obtained during the preliminary period of time, and means for calculating a degree of separation between the normal histogram the abnormal histogram for each of the feature values, and means for selecting a judgement feature value having a highest degree of separation among the feature values, and means for determining a threshold value of the judgment feature value depending on the degree of separation of the judgment feature value and means for transferring the threshold value of the judgment feature value to said measuring means for use in a subsequent period of measurement and analysis while said measuring means is disconnected from said measurement control means; and

display means for displaying the results of the analysis by said measuring means and the histogram generated by said measurement control means.

2. An organism signal measuring apparatus in accordance with claim 1, wherein the feature values include an area of a QRS portion, a peak value of the ORS portion and a value attained by dividing the area by the peak value.

3. An organism signal measuring apparatus in accordance with claim 2, wherein said measuring means measures electrocardiogram signals as the organism signals, differentiates the electrocardiogram signals to produce differentiation signals and determines a QRS portion in one of the electrocardiogram signals when an absolute value of a corresponding differentiation signal exceeds a predetermined threshold value.

4. An organism signal measuring apparatus for measuring organism signals of a subject for a predetermined period of time, comprising:

measuring means for measuring the organism signals for the predetermined period of time, including means for performing realtime analysis on the organism signals using a template matching method with templates unique to the subject producing the organism signals, to produce results of the analysis, and means for storing the results of the analysis until the predetermined period of time has passed and means for outputting the results of the analysis;

measurement control means for receiving the results of the analysis after the predetermined period of time, and receiving organism signals measured by said measuring means during a preliminary period of time to generate the templates for use in the template matching method using normal and abnormal organism signals with normality determined by an inspector, and means for determining threshold values of correlation coefficients for use in the template matching method, where each correlation coefficient CORRi is calculated for a QRS waveform F and a template Ti as CORRi=Ti·

F/|Ti||F| and means for transferring the threshold values of the correlation coefficients to said measuring means prior to separating said measuring means from said measurement control means for the predetermined period of time, said measuring means judging correlation exists between the QRS waveform F and the template Ti when CORRi>

TCR where TCR is the threshold value of the correlation coefficient CORRi; and

display means for displaying the results of the analysis.

5. An organism signal measuring apparatus in accordance with claim 4, wherein said measuring means determines correlation between the QRS waveform F and the template Ti when DNORM<

Tn where DNORM=ABS(|F|-|T)/|T and TN is a threshold value of DNORM.

6. An orgnaism signal measuring apparatus for measuring organism signals of a subject for a predetermined period of time, comprising:

measuring means for measuring the organism signals for the predetermined period of time, including means for performing realtime analysis on the organism signals using a template matching method with templates unique to the subject producing the organism signals, to produce results of the analysis, and means for storing the results of the analysis until the predetermined period of time has passed and means for outputting the results of the analysis;

measurement control means for receiving the results of the analysis after the predetermined period of time, and receiving organism signals measured by said measuring means during a preliminary period of time to generate the templates for use in the template matching method using normal and abnormal organism signals with normality determined by an inspector, and means for determining threshold values of correlation coefficients for use in the template matching method, where each said measuring means performing the template matching method using a renewed template Tin obtained from an old template Tio, a QRS waveform F and a renewal rate UR of the template according to Tin=(1-UR) Tio+UR·

F.

7. An organism signal measuring apparatus for measuring and analyzing organism signals of a subject for a predetermined period of time to produce analyzed data, comprising:

input means for inputting the organism signals of the subject;

measuring means for measuring the organism signals input via said input means for a predetermined period of time;

analyzing means for analyzing the organism signals according to feature values derived form the organism signals measured by said measuring means;

analysis data storing means for storing organism signal analysis data unique to the subject producing the organism signals measured by said measuring means, said analyzing means using the organism signal analysis data obtained from organism signals of the subject measured during a previous period of time to obtain feature values of normal and abnormal organism signals with normality judged by an inspector, a normal histogram and an abnormal histogram for each feature value, a degree of separation between the normal and abnormal histograms for each feature value, a feature value having a highest degree of separation selected as a judgement feature value for evaluating the organism signals and a threshold value of the judgement feature value, determined depending on the degree of separation of the judgement feature value, used by said analyzing means to judge the organism signals;

storing means for storing only the organism signals determined by said analyzing means to be abnormal; and

output means for outputting the organism signals stored in said storing means after completion of the predetermined period of time.

8. An organism signal measuring apparatus in accordance with claim 7, wherein the feature values include an area of a QRS portion, a peak value of the QRS portion and a value obtained by dividing the area by the peak value.

9. An organism signal measuring apparatus in accordance with claim 8, wherein said analyzing means analyzes electrocardiogram signals as the organism signals, differentiates the electrocardiogram signals to produce differentiation signals and determines a QRS portion in one of the electrocardiogram signals when an absolute value of a corresponding differentiation signal exceeds a predetermined thereshold value.

10. An organism signal measuring apparatus for measuring and analyzing organism signals of a subject for a predetermined period of time to produce analyzed data, comprising:

input means for inputting the organism signals of the subject;

measuring means for measuring the organism signals input via said input means for a predetermined period of time;

analyzing means for analyzing the organism signals, input by said input means, according to a template matching method;

analysis data storing means for storing organism signal analysis data obtained from the organism signals produced by the subject prior to the predetermined period of time, the organism signal analysis data including templates of normal and abnormal organism signals with normality judged by an inspector and threshold values of correlation coefficients where each correlation coefficient CORRi is calculated from a QRS waveform F and a template Ti according to CORRI=|Ti|·

|F|/|Ti.vertline.|F|, said analyzing means determining correlation between the QRS waveform F and the template Ti when CORRi>

TCR where TCR is the threshold value of CORRi;

storing means for storing only the organism signals determined by said analyzing means to be abnormal; and

output means for outputtting the organism signals stored in said storing means after completion of the predetermined period of time.

11. An organism signal measuring apparatus in accordance with claim 10, wherein said analyzing means determines correlation between the QRS waveform F and the template Ti when DNORM<

TN where DNORM=ABS(|F|-|T|)/|T.vertline. and TN is a threshold value of DNORM.

12. An organism signal measuring measuring apparatus for measuring and analyzing organism signals of a subjmect for a predetermined period of time to produce analyzed data, comprising:

input means for inputting the organism signals of the subject;

measuring means for measuring the organism signals input via said input means for a predetermined period of time;

analysis data storing means for storing organism signal analysis data unique to the subject producing the organism signals measured by said measuring means, the organism signal analysis data including templates and thresholds obtained from organism signals measured by said measuring means prior to the predetermined period;

analyzing means for analyzing the organism signals using the organism signal analysis data by performing a template matching method using a renewed template Tin obtained from an old template Tio, a QRS waveform F and a renewal rate UR of the template according to Tin =(1-UR)Tio+UR·

F;

storing means for storing only the organism signals determined by said analyzing means to be abnormal; and

output means for outputting the organism signals stored in said storing means after completion of the predetermined period of time.