Hemodialysis apparatus with automatic adjustment of dialysis solution flow

• US 5,092,836 A
• Filed: 03/19/1990
• Issued: 03/03/1992
• Est. Priority Date: 03/25/1989
• Status: Expired due to Fees

• Current Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius AG (Fresenius SE & Co. KGaA)
• Inventors: Polaschegg, Hans-Dietrich
• Primary Examiner(s): Hafer, Robert A.
• Assistant Examiner(s): Owens, Kerry
• Application Number:
  US07/495,363
• Time in Patent Office: 715 Days
• Field of Search: 604/4-6, 210/646, 210/85, 210/97, 210/149, 210/181, 210/321.65, 210/321.72, 210/650, 210/742
• US Class Current: 604/6.11
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/165 with a dialyser bypass on the dialysis fluid line
• CPC Class Codes: A61M 1/1672 using membrane filters, e.g. for sterilising the dialysate
• CPC Class Codes: A61M 1/36 Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
• CPC Class Codes: A61M 1/3607 Regulation parameters
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3313 used specific wavelengths
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/50 with microprocessors or computers

Abstract

The invention concerns a hemodialysis apparatus with a hemodialyser (10), which on the blood side has a blood pump (30) to convey blood from a patient to the dialyser (10) and on the dialysis solution side has a dialysis solution pump (20) to convey dialysis solution to the dialyser. The hemodialysis apparatus has a control device (100) whereby a signal derived from the magnitude of the blood flow is fed to the said device on the input side and whereby the said device gives a signal on the output side as a function of the blood flow in order to adjust the dialysis solution flow. With an automatic control device of this type dialysis concentrate, prepared water and energy can be saved. The predetermined control function can be a linear function. It can also be given in the form of numerical data which is fed into a matrix in the control device (100) which for every blood flow of one particular dialyser (10) gives a dialysis solution flow at which a certain percentage of clearance is achieved when the dialysis solution flow is continuous.

Claims

1. Hemodialysis apparatus adapted to receive from a patient in need of hemodialysis blood to be treated and to return treated blood to the patient, said hemodialysis apparatus comprising:

(a) a hemodialyzer having a blood side and a dialysis solution side,

(b) blood pumping means for conveying blood from the patient through the blood side of said hemodialyzer,

(c) dialysis solution pumping means for conveying dialysis solution through the dialysis side of said hemodialyzer,

(d) first control means having an input and an output,

(e) first means responsive to the volumetric rate of output of said blood pumping means for feeding into the input of said first control means an input signal which is a function of the volumetric rate of output of said blood pumping means,

(f) said first control means for generating at its output an output signal which is a predetermined function of the volumetric rate of output of said blood pumping means,

(g) second control means operatively connected to said dialysis solution pumping means for controlling the volumetric rate of output of said dialysis solution pumping means in response to signals communicated to said second control means,

(h) second means operatively interposed between the output of said first control means and said second control means for communicating to said second control means the out put signal generated at the output of said first control means,

(i) whereby to adjust the volumetric rate of output of said dialysis solution pumping means according to the predetermined function of the volumetric rate of output of said blood pumping means.

2. Hemodialysis apparatus as in claim 1, wherein said predetermined function is linear.

3. Hemodialysis apparatus as in claim 1, wherein said predetermined function is polynomial.

4. Hemodialysis apparatus as in claim 1, wherein said predetermined function is given in the form of numerical data which, for every volumetric rate of flow of blood for one dialysis, provides the volumetric rate of flow of dialysis solution required to attain a specific degree of blood purification.

5. Hemodialysis apparatus as in claim 1, wherein said second control means comprises a microprocessor.

6. Hemodialysis apparatus as in claim 1, further comprising:

(j) third means adapted to determine the temperature of said dialysis solution and to communicate to said second control means a control signal which is a function of said temperature,

(k) whereby to supplement the adjustment of the volumetric rate of output of said dialysis solution pumping means recited in (i).

7. Hemodialysis apparatus as in claim 6, wherein said third means comprises a first temperature sensoror upstream of the hemodialyzer and a second temperature sensor downstream of the hemodialyzer.

8. Method of treating the blood of a patient in need of hemodialysis in a hemodialyzer having a blood side and a dialysis solution side, blood pumping means adapted to convey blood from the patient through the blood side of the hemodialyzer and dialysis solution pumping means adapted to convey dialysis solution through the dialysis solution side of the hemodialyzer, said method comprising:

(a) sensing the volumetric rate of output of the blood pumping means,

(b) generating a first signal which is a function of the volumetric rate of output of said blood pumping means,

(c) generating a second signal which is a predetermined function of said first signal,

(d) employing said second signal to control the volumetric rate of output of said dialysis solution pumping means,

(e) whereby adjust the volumetric rate of output of said dialysis solution pumping means in accordance with said predetermined function.

9. Method as in claim 8, wherein said predetermined function is linear.

10. Method as in claim 8, wherein said predetermined function is polynomial.

11. Method as in claim 8, wherein said predetermined function is provided in the form of numerical data which, for every volumetric rate of flow of blood for one dialysis, provides the volumetric rate of flow of dialysis solution required to attain a specific degree of blood purification.

12. Method s in claim 8, further comprising:

(f) determining the temperature of said dialysis solution,

(g) generating a third signal which is a function of said temperature,

(h) employing said third signal to supplement the control of said dialysis solution pumping means.

13. Method as in claim 8, further comprising:

(f) determining the temperature of said dialysis solution upstream of said hemodialyzer,

(g) determining the temperature of said dialysis solution downstream of said hemodialyzer,

(h) generating a third signal which is a function of said temperatures,

(i) employing said third signal to supplement the control of said dialysis solution pumping means.