Method for the treatment of glaucoma

• US 5,092,837 A
• Filed: 08/27/1990
• Issued: 03/03/1992
• Est. Priority Date: 12/20/1989
• Status: Expired due to Fees

• Current Assignee: I-Med Development Corporation
• Original Assignee: I-Med Development Corporation
• Inventors: Ritch, Robert, Klein, Edward E.
• Primary Examiner(s): Yasko, John D.
• Assistant Examiner(s): Cermak, Adam J.
• Application Number:
  US07/573,323
• Time in Patent Office: 554 Days
• Field of Search: 604/8-11, 604/15-18, 604/49, 604/104, 604/164, 604/175, 604/264, 604/272, 604/274, 604/280, 604/294, 623/4, 606/108, 606/109
• US Class Current: 604/8
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202

Abstract

A method of permanently surgically treating glaucoma is disclosed together with an apparatus for effecting such treatment. In accordance with the method, an implant is disposed at a filtration site through the sclera the implant including a through going aperture leading from the anterior chamber to a bleb formed in the conjunctiva. The implant is retained in the sclera by radially compressing the same during the insertion procedure and thereafter releasing the radial compressive forces whereby the implant expands and is prevented from dislocation. An apparatus for effecting the implant is likewise disclosed, the apparatus including a cannula having a bore constraining the insert, a plunger for shifting the insert through an angularly offset opening in the cannula and a retainer filament engaged in the passage in the insert for controlling the precise location of the insert during the implant and for releasing the insert from connection to the cannula when the precise position is achieved.

Claims

1. The method of effecting a permanent reduction of intraocular pressure for the treatment of glaucoma comprising the steps of providing an implant member of resilient polymeric material, said member including an axially extending drain passage linking the ends thereof, a narrow neck portion and flanges at said ends, said flanges projecting radially outwardly beyond said neck portion in the unstressed condition of said implant, providing a cannula having a bore and a discharge tip at one end of said bore, mounting said implant member within said bore of said cannula adjacent said tip, said bore being dimensioned to deflect said flanges radially inwardly from said projected position, forming a fistula in the sclera of a patient said fistula extending between the anterior chamber of the eye and terminating beneath the conjunctiva, advancing said tip of said cannula through said fistula and thereafter ejecting said implant member outwardly through said tip in a position whereat said neck of said implant is disposed within said fistula, one said flange being disposed within said anterior chamber and the other said flange being disposed between the sclera and conjunctiva.

2. The method in accordance with claim 1 wherein said implant is ejected at an angle relative to the axis of said bore.

3. The method in accordance with claim 1 wherein said cannula includes a cutting edge at said tip, the method including the step of forming said fistula in said sclera by urging said cutting edge through the sclera.

4. An ab interno method of treating glaucoma in mammals by permanently surgically reducing intraocular pressure which comprises the steps of forming an incision in the anterior chamber of the eye at a position displaced from a proposed filtration site through the sclera, forming a raised conjunctival bleb at said filtration site, inserting a cannula through said incision, puncturing the sclera with said cannula in registry with said bleb, expelling a hollow tubular polymeric expansible insert from said cannula at a position in spanning relation of the puncture in said sclera, and thereafter causing the extremities of said expelled insert to expand at opposite sides of the sclera thereby to retain said insert against displacement from said spanning relation of the sclera.

5. The method of claim 4 wherein said insert is retained in compressed condition in said cannula and said expansion of said insert results from the release of said insert from said cannula.

6. The ab interno method of curing glaucoma in mammals by surgically reducing intraocular pressure which comprises the steps of forming an incision in the cornea leading to the anterior chamber of the eye at a position displaced from a proposed filtration site through the sclera, forming a conjunctival bleb in registry with said filtration site, forming a fistula through the sclera at said site in registry with said bleb, providing a hollow tubular polymeric insert having an axial extent exceeding the length of said fistula and having, in the unstressed condition thereof a radial extent at least at the distal ends thereof in excess of the transverse dimension of said fistula, advancing said insert through the anterior chamber and into spanning relating of said fistula, and thereafter causing said insert to be retained in said fistula by effecting a radial outward expansion of at least certain portions of said insert.