×

Antibody matrix device and method for evaluating immune status

  • US 5,100,777 A
  • Filed: 04/27/1987
  • Issued: 03/31/1992
  • Est. Priority Date: 04/27/1987
  • Status: Expired due to Term
First Claim
Patent Images

1. An immunoassay device comprising:

  • a. support having a substantially planar surface;

    b. an array of small, closely-spaced, discrete, antibody-coated areas on the support surface, the array containing antibody coated areas each area individually containing one of the following antibodies;

    a. antibody specific for surface antigen present on all mononuclear leukocytes;

    b. antibody specific for surface antigen present on all B lymphocytes;

    c. antibody specific for surface antigens present on all T lymphocytes;

    d. antibody specific for surface antigen present on helper/inducer T lymphocytes;

    e. antibody specific for surface antigen present on suppressor/cytotoxic T lymphocytes; and

    f. antibody specific for surface antigen present on monocytes; and

    c. a cover spaced from the support surface and positioned over the array of antibody coated areas,the cover having at least one aperture communicating with the interior of the chamber for introducing a suspension of leukocytes into the chamber, and,at least one additional aperture in the cover also communicating with the interior of the chamber to allow air to escape upon introduction of the sample into the chamber.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×