Endovascular filter and method for use thereof

• US 5,108,419 A
• Filed: 08/16/1990
• Issued: 04/28/1992
• Est. Priority Date: 08/16/1990
• Status: Expired due to Fees

• Current Assignee: Synectic Ventures III LLC (Synectic Asset Management, Inc.), Synectic Ventures II LLC (Synectic Asset Management, Inc.), Synectic Ventures I LLC (Synectic Asset Management, Inc.)
• Original Assignee: Evi Corp.
• Inventors: Kelly, Thomas L., Reger, Vincent A., Groshong, LeRoy E.
• Primary Examiner(s): Thaler, Michael H.
• Application Number:
  US07/568,844
• Time in Patent Office: 621 Days
• Field of Search: 606/200, 606/198, 606/159, 128/899
• US Class Current: 606/200
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A filter useful in tubular organs of the human body, intended primarily for endovascular use during surgical procedures for removal of plaque and other treatment of stenoses in arteries, in order to entrap particles of plaque or other materials freed from the interior wall of an artery while permitting continued flow of blood through the artery during the procedure of treating the stenosis. Several filter elements are fastened in apart-spaced relationship with one another along a flexible elongate member and are large enough to require the entire flow of blood through the artery to pass through the filter elements. An open-mouthed tubular stocking of porous filter material encloses the filter elements and supports the periphery of each filter element. Successive filter elements, progressing in the direction of blood flow, pass only progressively smaller particles. In a preferred embodiment, the mouth of the stocking can be closed to retain particles of material within the filter as it is written from the artery after repair of a stenosis.

Claims

1. An endovascular filter device, comprising:

(a) a slender flexible elongate support member having a proximal end and a distal end adapted for insertion into and along the interior of a blood vessel; and

(b) a filter assembly including;

(i) plurality of flexible filter elements attached to a portion of said elongate member and spaced apart from one another therealong adjacent said distal end;

(ii) a flexible tubular porous stocking surrounding said filter elements and interconnected with each of them, said stocking having a mouth directed generally toward said proximal end of said elongate member; and

(iii) means for supporting stocking with said mouth open to receive a flow of blood and with said filter elements in a flow-receiving and filtering position within said blood vessel.

2. The device of claim 1, including means associated with said stocking for selectively closing said mouth.

3. The filter device of claim 1 wherein each of said filter elements extends radially about said elongate support member and is attached thereto so as not to be movable longitudinally therealong, each of said filter elements having a periphery and said periphery of each of said filter elements being tightly interconnected with said stocking.

4. The device of claim 1 wherein said filter elements are each of flexible filter material preventing passage of particles larger than a predetermined maximum size, the maximum size of particles able to pass through respective ones of said filter elements located closer to said distal end of said flexible elongate member being smaller than the maximum size of particles able to pass through respective ones of said filter elements located further from said distal end of said flexible elongate member.

5. The device of claim 1 wherein said stocking is of a filter medium substantially preventing passage of particles which are larger than a predetermined size.

6. The device of claim 1 wherein said means for selectively closing said mouth includes a drawstring attached to said stocking and extending along said elongate flexible support member away from said distal end thereof.

7. The device of claim 1 wherein said elongate flexible support member includes a proximal portion which defines a lumen having an opening thereinto, located between said mouth of said stocking and said proximal portion, wherein said drawstring extends spirally along said flexible support member from said mouth of said stocking to said opening, so as selectively to draw said stocking into a furled configuration.

8. The device of claim 1 including a plurality of drawstrings arranged for coordinated application of tension thereto for drawing said stocking and said filter elements into a furled configuration.

9. The device of claim 1 wherein said elongate flexible support member is a guide wire and includes a flexible tip portion extending distally beyond all of said filter elements.

10. The device of claim 9 wherein said guide wire has a reduced diameter portion to which said filter elements are attached, said tip portion being larger in diameter than reduced diameter portion.

11. The device of claim 1 wherein at least one of said plurality of filter elements is generally conical.

12. The device of claim 1 including a set of flexible resilient ribs extending radially from said flexible elongate support member adjacent one of said filter elements so as to urge said filter element toward a radially extended configuration.

13. The device of claim 12 wherein said elongate support member includes first and second parts, and at least one tension support extending between and being interconnected with both the mouth of said stocking and said first part of said elongate support member, and said stocking having a distal end attached to said second part of said elongate support member, said second part being movable, between a first position, in which said tension support is sufficiently slackened to allow said resilient ribs to move a respective one of said filter elements toward said radially extending configuration, and a second position, in which said stocking and said tension support are in tension overcoming said resilient ribs and drawing said filter element radially inward toward said elongate support member.

14. The device of claim 13 wherein said first part of said elongate support member is a catheter defining a lumen and said second part thereof is a core longitudinally and rotatably movable within said lumen between said first and second positions.

15. A method of relieving a stenosis in an artery, comprising:

(a) providing an endovascular filter device including a plurality of flexible filter elements attached to an elongate flexible guide wire and surrounded by a tubular stocking of flexible filter medium attached to said filter elements;

(b) forming an opening in an artery in a location proximal of a stenosis and inserting said guide wire into said artery through said opening, with said filter elements and said stocking in a furled configuration;

(c) extending said filter device into said artery until said filter elements and stocking have passed through and a predetermined distance beyond a stenotic portion of said artery;

(d) thereafter unfurling said stocking and filter elements so as to deploy said filter elements across the interior of said artery;

(e) thereafter enlarging the lumen of said artery by freeing pieces of material from the stenotic portion of said artery; and

(f) entrapping said pieces of material thus freed from said stenotic portion within said stocking.

16. The method of claim 15, including the further steps of closing said stocking so as to retain said pieces of material within said stocking, and withdrawing said filter device from said artery with said pieces of material retained within stocking.

17. The method of claim 16, said tubular stocking having a diameter, including the step of reducing the diameter of said stocking to a reduced diameter by twisting said stocking about said guide wire prior to removing said filter device from said artery.

18. The method of claim 16 wherein said stocking includes a mouth, the method including drawing said mouth tightly closed as part of said step of closing said stocking.

19. The method of claim 15, including the further step of monitoring blood pressure downstream of said filter device while freeing said material from said stenotic portion of said artery, and withdrawing said filter device from within said artery in response to a predetermined decrease in blood pressure downstream.

20. The method of claim 15 including the step of moving said filter device along said artery toward the location of said stenosis in a deployed configuration after performing said step of freeing pieces of material, so as to sweep said pieces of material away from the interior surface of said artery.

21. An endovascular filter device, comprising:

(a) a slender flexible elongate support member having a proximal end and a distal end adapted for insertion into and along the interior of a blood vessel; and

(b) a filter assembly including;

(i) plurality of flexible filter elements attached to a portion of said elongate member and spaced apart from one another therealong adjacent said distal end;

(ii) a flexible tubular porous stocking surrounding said filter elements and interconnected with each of them, said stocking having a mouth directed generally toward said distal end of said elongate member; and

(iii) means for supporting said tubular stocking with said mouth open to receive a flow of blood and with said filter elements in a flow-receiving and filtering position within said blood vessel.

22. The device of claim 21, including means associated with said stocking for selectively closing said mouth.

23. The filter device of claim 21 wherein each of said filter elements extends radially about said elongate support member and is attached thereto so as not to be movable longitudinally therealong, each of said filter elements having a periphery and said periphery of each of said filter elements being tightly interconnected with said stocking.

24. The device of claim 21 wherein said filter elements are each of flexible filter material preventing passage of particles larger than a predetermined maximum size, the maximum size of particles able to pass through respective ones of said filter elements located closer to said distal end of said flexible elongate member being greater than the maximum size of particles able to pass through respective ones of said filter elements located further from said distal end of said flexible elongate member.

25. The device of claim 21 wherein said stocking is of a filter medium substantially preventing passage of particles which are larger than a predetermined size.

26. The device of claim 21 wherein said means for selectively closing said mouth includes a drawstring attached to said stocking and extending along said elongate flexible support member toward said distal end thereof.

27. The device of claim 21 including a plurality of drawstrings arranged for coordinated application of tension thereto for drawing said stocking and said filter elements into a furled configuration.

28. The device of claim 21 wherein said elongate flexible support member is a guide wire and includes a flexible tip portion extending distally beyond all of said filter elements.

29. The device of claim 28 wherein said guide wire has a reduced diameter portion to which said filter elements are attached, said tip portion being larger in diameter than reduced diameter portion.

30. The device of claim 21 including a set of flexible resilient ribs extending radially from said flexible elongate support member adjacent one of said filter elements so as to urge said filter element toward a radially extended configuration.

31. A method of relieving a stenosis in a blood vessel, comprising the steps of:

(a) providing an endovascular filter device, including a slender flexible elongate support member having a proximal end and a distal end adapted for insertion into and along the interior of a blood vessel and a flexible tubular porous stocking surrounding a portion of said elongate support member, the stocking having a mouth directed generally toward said distal end of said elongated member, as well as a closed end surrounding said elongate member and located more proximally along said elongate member than the location of said mouth, and means for supporting said tubular stocking with said mouth open to receive a flow of blood;

(b) forming an opening in a blood vessel in a location downstream of a stenotic portion thereof by reference to the normal flow of blood, and inserting said flexible elongate support member into said blood vessel through said opening, with said stocking in a furled configuration;

(c) extending said filter device into said blood vessel until said stocking has approached to within a predetermined distance from said stenotic portion on a downstream side of said stenotic portion of said blood vessel;

(d) thereafter unfurling said stocking so as to deploy said stocking within said blood vessel with said mouth of said stocking substantially in intimate contact with the interior of said blood vessel;

(e) thereafter enlarging the lumen of said blood vessel by freeing pieces of material from said stenotic portion thereof;

(f) entrapping within said stocking said pieces of material thus freed from said stenotic portion; and

(g) reducing the diameter of said stocking to a reduced diameter by twisting said stocking about said flexible elongate support member prior to removing said filter from said blood vessel.

32. A method of relieving a stenosis in a blood vessel, comprising the steps of:

(a) providing an endovascular filter device, including a slender flexible elongate support member having a proximal end and a distal end adapted for insertion into and along the interior of a blood vessel and a flexible tubular porous stocking surrounding a portion of said elongate support member, said tubular porous stocking having an interior and including a plurality of flexible filter elements attached to said elongate support member and spaced apart from one another therealong within said flexible tubular porous stocking, each of said filter elements being interconnected with the interior of said tubular porous stocking, the stocking having a mouth directed generally toward said distal end of said elongate member, as well as a closed end surrounding said elongate member and located more proximally along said elongate member than the location of said mouth, and means for supporting said tubular stocking with said mouth open to receive a flow of blood;

(b) forming an opening in a blood vessel in a location downstream of a stenotic portion thereof by reference to the normal flow of blood, and inserting said flexible elongate support member into said blood vessel through said opening, with said stocking in a furled configuration;

(c) extending said filter device into said blood vessel until said stocking has approached to within a predetermined distance from said stenotic portion on a downstream side of said stenotic portion of said blood vessel;

(d) thereafter unfurling said stocking so as to deploy said stocking within said blood vessel with said mouth of said stocking substantially in intimate contact with the interior of said blood vessel;

(e) thereafter enlarging the lumen of said blood vessel by freeing pieces of material from said stenotic portion thereof; and

(f) entrapping within said stocking said pieces of material thus freed from said stenotic portion.

33. An endovascular filter device, comprising:

(a) a slender flexible elongate support member having a proximal end and a distal end adapted for insertion into and along the interior of a blood vessel; and

(b) a filter assembly including;

(i) a flexible tubular porous stocking surrounding a portion of said elongate support member proximate said distal end and having a closed end attached to said elongate support member and a mouth directed generally toward said proximal end of said elongate support member;

(ii) means for supporting said tubular porous stocking with said mouth open to receive a flow of blood in a flow-receiving and filtering position within said blood vessel; and

(iii) selectively operable means associated with said mouth for closing said mouth about said elongate support member and twisting said stocking about said elongate support member to retain materials filtered from said flow of blood within said stocking, said selectively operable means including a drawstring interconnecting said elongate support member and said mouth, and means extending through said elongate support member for controlling said drawstring in order to close said mouth and twist said stocking about said elongate support member.