Method and apparatus for amperometric diagnostic analysis
First Claim
1. A method of measuring the amount of a selected compound in body fluids comprising,a) providing a measuring cell having at least a first and second electrode and said cell containing an oxidant and a buffer,b) placing a sample of fluid to be tested in said cell,c) reconstituting said oxidant and buffer with said sample fluid to generate a predetermined reaction,d) allowing said reaction to proceed substantially to completion,e) applying a potential across said electrodes and sample, andf) measuring the resulting Cottrell current to determine the concentration of said selected compound present in said sample.
8 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to a novel method and apparatus for the amperometric determination of an analyte, and in particular, to an apparatus for amperometric analysis utilizing a novel disposable electroanalytical cell for the quantitative determination of biologically important compounds from body fluids.
-
Citations
11 Claims
-
1. A method of measuring the amount of a selected compound in body fluids comprising,
a) providing a measuring cell having at least a first and second electrode and said cell containing an oxidant and a buffer, b) placing a sample of fluid to be tested in said cell, c) reconstituting said oxidant and buffer with said sample fluid to generate a predetermined reaction, d) allowing said reaction to proceed substantially to completion, e) applying a potential across said electrodes and sample, and f) measuring the resulting Cottrell current to determine the concentration of said selected compound present in said sample.
-
7. A method for measuring the amount of glucose in blood, comprising
a) providing a measuring cell having at least a first and second electrode and said cell containing an oxidant, a buffer and an enzyme, b) placing a blood sample to be tested in said cell, c) reconstituting said oxidant, buffer and enzyme with said blood sample to generate a predetermined reaction, d) essentially immediately applying a potential across said electrodes and blood sample, and e) measuring the resultant Cottrell current when the reaction has proceeded to completion to determine the concentration of said glucose present in blood sample.
Specification