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Chemiluminescence assay of in vivo inflammation

  • US 5,108,899 A
  • Filed: 10/31/1989
  • Issued: 04/28/1992
  • Est. Priority Date: 10/31/1989
  • Status: Expired due to Fees
First Claim
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1. A method of evaluating the in vivo state of inflammation of a patient, comprising:

  • a) determining the extent of opsonin receptor expression on phagocytes in a first portion of a phagocyte-containing biological sample of a patient,b) contacting a second portion of the biological sample with receptor expression priming agent to obtain maximal expression of opsonin receptors on phagocytes in the second portion of the biological sample;

    c) determining the extend of opsonin receptor expression on phagocytes in the second portion of the sample; and

    thend) comparing the extent of opsonin receptor expression on the phagocytes of the first and second portions of the sample as a measure of the in vivo state of inflammation of the patient.

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