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Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles

  • US 5,110,727 A
  • Filed: 05/10/1988
  • Issued: 05/05/1992
  • Est. Priority Date: 04/03/1987
  • Status: Expired due to Term
First Claim
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1. In a coagulation assay comprising combining a coagulation assay reagent and a whole blood sample or plasma sample and obtaining a coagulation assay measurement, the improvement comprising adding to a dry coagulation assay reagent containing magnetic particles distributed substantially homogeneously therethrough, arranged in a substantially flattened format, and under the influence of an oscillating magnetic field or moving permanent magnetic field, or both, a whole blood sample or a plasma sample thereby substantially simultaneously initiating movement of said magnetic particles and the coagulation assay measurement and monitoring movement of said magnetic particles to obtain said assay measurement.

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