Method for preserving blood fluid

• US 5,114,672 A
• Filed: 08/27/1990
• Issued: 05/19/1992
• Est. Priority Date: 08/27/1990
• Status: Expired due to Fees

• Current Assignee: Cryo-Cell International Incorporated
• Original Assignee: Cryo-Cell International Incorporated
• Inventors: Richard, Daniel D., Knippscheer, Hermann
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): NOT, DEFINED
• Application Number:
  US07/573,646
• Time in Patent Office: 631 Days
• Field of Search: 422/1, 422/41, 422/44, 422/40, 436/8, 436/18, 604/4, 604/5, 604/6, 435/1, 435/2, 600/36, 623/1, 623/12
• US Class Current: 435/1.1
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 5/150038 for blood from umbilical cord
• CPC Class Codes: A61B 5/150045 for blood from vagina, placenta, colon or mouth
• CPC Class Codes: A61B 5/417 the bone marrow
• CPC Class Codes: A61M 1/02 Blood transfusion apparatus blood infusion by syringes A61M5/14
• CPC Class Codes: A61M 2202/0462 Placental blood, umbilical cord blood
• CPC Class Codes: A61M 2210/1458 Placenta
• CPC Class Codes: A61M 2210/1466 Umbilical cord
• CPC Class Codes: Y10T 436/10 Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
• CPC Class Codes: Y10T 436/108331 Preservative, buffer, anticoagulant or diluent

Abstract

In a method for preserving umbilical cord blood, a severed umbilical cord is provided which has at least one tubular blood vessel closed at opposite ends to maintain fluid in the vessel. An anticoagulant is added to blood fluids in the vessel, and the blood fluid is moved in the vessel to distribute the anticoagulant throughout the blood. An associated apparatus comprises a container, a support within the container for supporting an umbilical cord, an injector or other fluid adding device engageable with the umbilical cord in the container for introducing an anticoagulant into at least one tubular vessel in the umbilical cord, and a fluid moving device at least partially inside the container for moving blood fluid contained in the tubular vessel.

Claims

1. A method for treating fluid including blood, comprising the steps of:

providing an umbilical cord closed at opposite ends and containing a blood fluid to be treated;

adding through said umbilical cord an additive to said blood fluid in said umbilical cord; and

moving said blood fluid in said umbilical cord to distribute said additive throughout said blood fluid in said umbilical cord.

2. The method according to claim 1 wherein said step of moving includes the steps of opening said umbilical cord at said opposite ends and connecting said umbilical cord at said opposite ends to a pump and operating said pump to circulate said blood fluid in said umbilical cord.

3. The method according to claim 2 wherein said step of adding is performed during at least a portion of said step of pumping, said step of adding thus including a gradual addition of said additive to said blood fluid through said umbilical cord.

4. The method according to claim 3 wherein said step of adding comprises the step of aspirating said additive into said blood fluid of said umbilical cord.

5. The method according to claim 1 wherein said step of adding comprises the step of aspirating said additive into said blood fluid of said umbilical cord.

6. The method according to claim 1 wherein said step of adding comprises the step of injecting said additive into said blood fluid of said umbilical cord.

7. The method according to claim 1 wherein said step of moving includes the step of vibrating or shaking said umbilical cord.

8. The method according to claim 1 wherein said step of moving includes the step of squeezing said umbilical cord.

9. The method according to claim 1 wherein said step of moving includes the step of rolling a roller along a portion of said umbilical cord.

10. The method according to claim 1, further comprising the step of placing said umbilical cord into a transport and storage container;

and

manipulating said umbilical cord in said transport and storage container to move said blood fluid within said umbilical cord.

11. The method according to claim 10 wherein said step of manipulating includes the step of vibrating or shaking said umbilical cord.

12. The method according to claim 10 wherein said step of manipulating includes the step of squeezing said umbilical cord.

13. The method according to claim 10 wherein said step of manipulating includes the step of rolling a roller along said umbilical cord.

14. The method according to claim 10, further comprising the step of controlling the temperature in said transport and storage container.

15. The method according to claim 1 wherein said additive is an anticoagulant.

16. The method according to claim 15 wherein said step of providing includes the steps of providing a placenta with said umbilical cord connected thereto, closing a free end of said umbilical cord, manipulating said placenta to force blood therefrom into said umbilical cord, closing an end of said umbilical cord opposite said free end, and severing said umbilical cord from said placenta, while maintaining opposite ends of said umbilical cord closed.

17. A method for treating fluid including blood, comprising the steps of:

providing an umbilical cord closed at opposite ends and containing a blood fluid to be treated; and

at least partially automatically moving said fluid in said umbilical cord to prevent coagulation of blood in said fluid.

18. The method according to claim 17 wherein said step of moving includes the step of at least partially automatically vibrating or shaking said umbilical cord.

19. The method according to claim 17 wherein said step of moving includes the step of at least partially automatically squeezing said umbilical cord.

20. The method according to claim 17 wherein said step of moving includes the step of at least partially automatically rolling a roller along a portion of said umbilical cord.