Method for drug administration

• US 5,116,311 A
• Filed: 10/25/1990
• Issued: 05/26/1992
• Est. Priority Date: 11/30/1987
• Status: Expired due to Term

• Current Assignee: ABet Astra
• Original Assignee: Sigmund J. Lofstedt
• Inventors: Lofstedt, Sigmund J.
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): CLARKE, ROBERT A
• Application Number:
  US07/602,393
• Time in Patent Office: 579 Days
• Field of Search: 604/49, 604/54, 604/93, 604/94, 604/131, 604/246, 604/257, 128/898, 128/200.14, 128/200.22, 128/200.21
• US Class Current: 604/516
• CPC Class Codes: A61M 2210/0618 Nose
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 3/0262 manually, e.g. by squeezing a bulb

Abstract

A new method for administration of pharmacological solutions into the nasal cavity whereby the patient'"'"'s head is being bent forward 55°-90° from an upright position as well as a device for use in the administration. The method makes it possible to irrigate or treat the whole or nearly the whole mucous membrane in the nasal cavity with solutions or suspensions without any risk for their reaching the digestive tract through the pharynx.

Claims

1. A method for the administration of drugs in solutions into one nasal cavity comprising the steps of:

bending the patient'"'"'s head forward between 55°

-90°

from an upright position so that the opening between the nasal cavity and the pharynx is positioned higher than the opening between the two nasal cavities; and

introducing a drug-containing solution into one nostril, while the other nostril remains open to the air, in an amount to substantially fill the one nasal cavity and in a manner to allow any excess solution to flow into and drain freely from the other nasal cavity so as to avoid flowing down the pharynx.

2. A method according to claim 1, wherein the patient'"'"'s head is bent forward at an angle of about 60°

.

3. A method according to claim 1, wherein the patient'"'"'s head is bent forward at an angle of about 90°

so that solution covers the osties of the rear ethmoidal cells and sphenoidal sinus.

4. A method according to claim 1, wherein the solution is administered through a device having an upper opening part that tightly fits a human nostril, and comprising the step of maintaining solution in the nasal cavity for a selected period of time.

5. A method according to claim 4, comprising the step of alternatively withdrawing and reintroducing solution through said upper opening part, so as to keep the solution in said nasal cavity in motion.

6. A method according to claim 4, wherein solution is introduced through said upper opening part without spraying.

7. A method according to claim 6, comprising the steps of storing the solution in a compressible container and supplying the solution to said upper opening part by squeezing the container.

8. A method according to claim 6, comprising the steps of storing the solution in a rigid container and of controlling the supply of solution to said upper opening part by varying the height of the container.