Variable intensity remote controlled needleless injectors

• US 5,116,313 A
• Filed: 08/31/1990
• Issued: 05/26/1992
• Est. Priority Date: 08/31/1989
• Status: Expired due to Fees

• Current Assignee: Her Majesty The Queen In Right of Canada As Represented By The Minister of National Defence
• Original Assignee: Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Industry, Through The Communications Research Centre Canada
• Inventors: McGregor, Gavin
• Primary Examiner(s): Coven, Edward M.
• Assistant Examiner(s): Passaniti, Sebastiano
• Application Number:
  US07/576,609
• Time in Patent Office: 634 Days
• Field of Search: 604/68-72, 604/134, 604/135, 604/141, 604/150, 81/9.22
• US Class Current: 604/70
• CPC Class Codes: A61M 2005/2086 having piston damping means, e.g. axially or rotationally acting retarders
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion
• CPC Class Codes: A61M 5/482 Varying injection pressure, e.g. by varying speed of injection

Abstract

An apparatus for injecting liquids into a body without using hypodermic needles, the liquid being ejected from a small orifice in a probe at a velocity which will penetrate the surface of a body against which the probe is placed. The apparatus ejects a specific small volume of the liquid under a very high initial velocity and pressure followed by the ejection of the main charge of liquid at a lower velocity so that the liquid flows into the channel caused by the initial penetration without penetrating to a greater depth. The probe is connected to a hand-held portion whose other end is attached via a flexible tube containing a suitable hydraulic fluid to two remote pressure intensifiers, one of which creates the required high initial pressure for a short period of time and the other of which provides the pressure necessary to eject the main charge of liquid at a lower velocity. The second intensifier is synchronized electronically or mechanically to follow the initial pulse when its pressure decays to the main charge injection pressure. The pressures created by the high pressure intensifier and second pressure intensifier are individually adjustable for various type of situations, such as depth of penetration or skin conditions.

Claims

1. An apparatus for injecting liquid into a body through a penetrable skin thereof, comprising a slim hand-held portion having a restricted orifice in a tip at its free end and its other end connected to a high pressure flexible tube containing hydraulic fluid, said flexible tubing being connected to remote pressure intensifier means, said hand-held portion comprising a first cylinder within said hand-held portion communicating with said orifice, a first piston movable in said first cylinder, movement of the first piston towards said orifice ejecting any liquid placed in the first cylinder out through the orifice, a second cylinder in said hand-held portion co-axial with said first cylinder, a second piston movable in said second cylinder and connected to said first piston, the second piston being spring-biased towards said other end and communicating with the hydraulic fluid in said flexible tube;

and said remote pressure intensifier means comprising a first high pressure intensifier provided with a first adjustable drive system to provide a high initial pressure pulse through the hydraulic fluid to said second piston and a second low pressure intensifier consisting of a third cylinder containing a third piston which is in contact with the hydraulic fluid, the third piston being movable by a second adjustable drive system to transfer a low secondary pressure via the hydraulic fluid to the second piston.

2. An apparatus as defined in claim 1, wherein said pressure intensifiers are located in a sound absorbing enclosure.

3. An apparatus as defined in claim 2, wherein the first high pressure intensifier consists of a first plunger and a fourth piston in a fourth cylinder with the first plunger being movable by the first adjustable drive system so it can provide an impact to the fourth piston providing said high initial pressure pulse.

4. An apparatus as defined in claim 3, wherein the third piston is connected to a second plunger and the first and second adjustable drive systems are first and second solenoid coils which are associated with the first and second plungers respectively, the first and second plungers consisting of magnetic material with currents applied to the first and second solenoid coils being adjustable.

5. An apparatus as defined in claim 4, wherein a mechanical arrangement is included to adjust the rest position of the second plunger and thereby the third piston in the third cylinder, which provides a predetermined maximum stroke for the third piston in the third cylinder.

6. An apparatus as defined in claim 5, wherein the fourth cylinder consist of a first small cylinder in which the fourth piston is movable and a coaxial larger cylinder that contains another piston which is connected to said fourth piston;

said larger cylinder being coaxial with a slightly smaller cylinder to which it is joined by a stepped portion, the first solenoid coil surrounding said slightly smaller cylinder with the first plunger being movable in said slightly smaller cylinder under the influence of said first solenoid coil, said another piston being biased against the stepped portion by a spring and separated from the first plunger by a gap.

7. An apparatus as defined in claim 6, wherein said another piston contains a cavity with a central opening facing said slightly smaller cylinder, the width of said central opening being smaller than the width of the cavity;

an adjustment rod extending through said central opening into said slightly smaller cylinder and being attached to an enlarged base which is located in said cavity, the base having a width larger than said central opening with the rest position of the base in said cavity being adjustable by said rod, the side of the cavity containing said central opening in co-operation with said enlarged base acting as a stop to limit the distance through which said another piston can move when impacted by the first plunger.

8. An apparatus as defined in claim 7, wherein the first plunger is cylindrical with a central bore and said rod extends through the central bore of the first plunger, the rod being connected to an external micrometer adjustment mechanism which can adjust stroke through which said another piston can move.

9. An apparatus as defined in claim 1, wherein an attachment for filling the first cylinder with liquid medication consists of a thin hollow needle with an integral cap having an opening in communication with the hollow needle, the needle and cap being embedded in a cylindrical collet with the needle protruding from one end of the collet which has a central cylindrical opening co-axial with the needle and extending to the other end of the collet, the cap being located at an inner end of the cylindrical opening which is of a size in which the hand-held portion will fit.

10. An apparatus as defined in claim 9, wherein the outer surface of said one end of the collet is threaded and an internally threaded collet is threaded onto said one end;

the collet which is threaded on its outer surface having flexible fingers around its circumference extending past said one end, the free end of the fingers having inwardly extending hooks which are biased inwardly to clamp around the rim of a bottle which contains liquid medication as the attachment is pressed against the rim with the needle penetrating a seal for that bottle.

11. An apparatus as defined in claim 1, wherein the second adjustable drive system consists of a rotary electrical motor connected to a transmission system that converts rotary motion to linear motion which is applied by a linear actuator to said third piston.

12. An apparatus as defined in claim 11, wherein the hydraulic fluid in said third cylinder is in communication with hydraulic fluid in a flexible tube which is attached to an inlet of a return flow check valve in a junction block with an outlet of the check valve being in communication with the high pressure flexible tube at a T-connection in the junction block.

13. An apparatus as defined in claim 12, wherein the check valve is provided with a manually operated device that can form a path allowing hydraulic fluid to flow from the high pressure flexible tube back into said third cylinder.

14. An apparatus as defined in claim 12, wherein the first high pressure intensifier consists of an additional piston in an additional cylinder whose outlet is connected to another inlet of said T-connection, a platform being attached to an additional piston rod associated with said additional piston and spaced a short distance from a weight attached to a drive rod of a solenoid whose supply current is adjustable to impact the weight against said platform with a predetermined adjustable force.

15. An apparatus as defined in claim 14, wherein the check valve is provided with a manual operated device that can form a path allowing hydraulic fluid to flow from the high pressure flexible tube back into said third cylinder.

16. An apparatus as defined in claim 14, wherein a power supply to said solenoid is adjustable to move said weight with a reciprocating motion to provide a series of impacts against said platform, a spring returning the platform to its rest position between impacts.

17. An apparatus as defined in claim 16, wherein the check valve is provided with a manual operated device that can form a path allowing hydraulic fluid to flow from the high pressure flexible tube back into said third cylinder.

18. An apparatus as defined in claim 14, wherein the additional cylinder is located in a first block having a recess portion in its surface surrounding the additional piston rod which is connected to said additional piston, the additional piston rod having an enlarged portion located in said recess portion, a cover with a central circular opening which is smaller than said enlarged portion being attached to said surface with the additional piston rod extending through said central circular opening to said platform, the cover and surface of said recess portion opposite said cover in co-operation with said enlarged portion form stops for the motion of the enlarged portion and limit the stroke of the additional piston in the additional cylinder.

19. An apparatus as defined in claim 18, wherein a power supply to said solenoid is adjustable to move said weight with a reciprocating motion to provide a series of impacts against said platform, a spring returning the platform to its rest position between impacts.

20. An apparatus as defined in claim 19, wherein said spring is located between the platform and the cover.

21. An apparatus as defined in claim 18, wherein the check valve is provided with a manual operated device that can form a path allowing hydraulic fluid to flow from the high pressure flexible tube back into said third cylinder.